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8P2W
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BU of 8p2w by Molmil
Structure of human SIT1 (focussed map / refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Sodium- and chloride-dependent transporter XTRP3
著者Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B.
登録日2023-05-16
公開日2024-06-12
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2.
Nat Commun, 15, 2024
5W4S
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BU of 5w4s by Molmil
Solution structure of C2 domain from protein kinase C alpha in ternary complex with calcium and V5-pHM peptide
分子名称: CALCIUM ION, Protein kinase C alpha type, V5-pHM peptide
著者Yang, Y, Igumenova, T.I.
登録日2017-06-12
公開日2018-04-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Basis of Protein Kinase C alpha Regulation by the C-Terminal Tail.
Biophys. J., 114, 2018
8OMU
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BU of 8omu by Molmil
Cryo-EM structure of rat SLC22A6 bound to alpha-ketoglutaric acid in a low occupancy state
分子名称: Solute carrier family 22 member 6, Synthetic nanobody (Sybody)
著者Parker, J.L, Kato, T, Newstead, S.
登録日2023-03-31
公開日2023-07-19
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
1JLJ
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BU of 1jlj by Molmil
1.6 Angstrom crystal structure of the human neuroreceptor anchoring and molybdenum cofactor biosynthesis protein gephyrin
分子名称: FORMIC ACID, SODIUM ION, gephyrin
著者Schwarz, G, Schrader, N, Mendel, R.R, Hecht, H.-J, Schindelin, H.
登録日2001-07-16
公開日2001-09-21
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of human gephyrin and plant Cnx1 G domains: comparative analysis and functional implications.
J.Mol.Biol., 312, 2001
1B7V
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BU of 1b7v by Molmil
Structure of the C-553 cytochrome from Bacillus pasteruii to 1.7 A resolution
分子名称: HEME C, PROTEIN (CYTOCHROME C-553)
著者Gonzalez, A, Benini, S, Rypniewski, W.R, Wilson, K.S, Ciurli, S.
登録日1999-01-22
公開日2000-03-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of oxidized Bacillus pasteurii cytochrome c553 at 0.97-A resolution.
Biochemistry, 39, 2000
2XE8
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BU of 2xe8 by Molmil
The complete reaction cycle of human phosphoglycerate kinase: The open ternary complex with 3PG and AMP-PNP
分子名称: 3-PHOSPHOGLYCERIC ACID, PHOSPHOGLYCERATE KINASE 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Cliff, M.J, Baxter, N.J, Blackburn, G.M, Merli, A, Vas, M, Waltho, J.P, Bowler, M.W.
登録日2010-05-11
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase.
J.Biol.Chem., 286, 2011
1OMD
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BU of 1omd by Molmil
STRUCTURE OF ONCOMODULIN REFINED AT 1.85 ANGSTROMS RESOLUTION. AN EXAMPLE OF EXTENSIVE MOLECULAR AGGREGATION VIA CA2+
分子名称: CALCIUM ION, ONCOMODULIN
著者Ahmed, F.R, Przybylska, M, Rose, D.R, Birnbaum, G.I, Pippy, M.E, Macmanus, J.P.
登録日1990-04-19
公開日1991-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of oncomodulin refined at 1.85 A resolution. An example of extensive molecular aggregation via Ca2+.
J.Mol.Biol., 216, 1990
7AAC
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BU of 7aac by Molmil
Crystal structure of the catalytic domain of human PARP1 in complex with veliparib
分子名称: (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, Poly [ADP-ribose] polymerase 1, SULFATE ION
著者Schimpl, M, Ogden, T.E.H, Yang, J.-C, Easton, L.E, Underwood, E, Rawlins, P.B, Johannes, J.W, Embrey, K.J, Neuhaus, D.
登録日2020-09-04
公開日2021-01-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.593 Å)
主引用文献Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.
Nucleic Acids Res., 49, 2021
6XVH
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BU of 6xvh by Molmil
carbonic anhydrase with bound arylsulfonamide- boronic acid
分子名称: (4-sulfamoylphenyl)boronic acid, Carbonic anhydrase 2, ZINC ION
著者Perez, C, Zhang, B.
登録日2020-01-22
公開日2021-02-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An easy to assemble, fully modulable, selectiv and colorimetric artificial bio-sensor for fingerprintting the recognition of neurotransmitters
To Be Published
8BFJ
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BU of 8bfj by Molmil
CNOT11-GGNBP2 complex
分子名称: 1,2-ETHANEDIOL, CCR4-NOT transcription complex subunit 11, Gametogenetin-binding protein 2
著者Basquin, J, Ozgur, S, Conti, E.
登録日2022-10-26
公開日2022-12-28
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions.
Cell Rep, 42, 2023
8B7W
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BU of 8b7w by Molmil
Complex IL-17A/anti-IL-17A-76
分子名称: CHLORIDE ION, GLYCEROL, Interleukin-17A, ...
著者Kostareva, O.S, Svoeglazova, A, Kolyadenko, I.A, Dzhus, U.F, Tishchenko, S.V, Gabdulkhakov, A.G.
登録日2022-10-03
公開日2022-12-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Two Epitope Regions Revealed in the Complex of IL-17A and Anti-IL-17A V H H Domain.
Int J Mol Sci, 23, 2022
3CMX
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BU of 3cmx by Molmil
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DAP*DA)-3'), DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DTP*DT)-3'), ...
著者Pavletich, N.P.
登録日2008-03-24
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
6YXX
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BU of 6yxx by Molmil
State A of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
分子名称: 12S ribosomal RNA, 50S ribosomal protein L13, putative, ...
著者Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
登録日2020-05-04
公開日2020-10-14
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
8EDG
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BU of 8edg by Molmil
Cryo-EM structure of the Hermes transposase bound to two left-ends of its DNA transposon
分子名称: DNA (46-MER), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), DNA (55-MER), ...
著者Lannes, L, Dyda, F.
登録日2022-09-04
公開日2023-08-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.64 Å)
主引用文献Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
6YVV
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BU of 6yvv by Molmil
Condensin complex from S.cerevisiae ATP-free apo bridged state
分子名称: Condensin complex subunit 1,Ycs4, Condensin complex subunit 2,Brn1, Structural maintenance of chromosomes protein 2,Structural maintenance of chromosomes protein 2, ...
著者Lee, B.-G, Cawood, C, Gutierrez-Escribano, P, Nakane, T, Merkel, F, Hassler, M, Haering, C.H, Aragon, L, Lowe, J.
登録日2020-04-28
公開日2020-07-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
Nat.Struct.Mol.Biol., 27, 2020
7RMA
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BU of 7rma by Molmil
Structure of the fourth UIM (Ubiquitin Interacting Motif) of ANKRD13D in complex with a high affinity UbV (Ubiquitin Variant)
分子名称: Ankyrin repeat domain-containing protein 13D, SODIUM ION, SULFATE ION, ...
著者Singer, A.U, Manczyk, N, Veggiani, G, Sicheri, F, Sidhu, S.S.
登録日2021-07-27
公開日2022-05-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Panel of Engineered Ubiquitin Variants Targeting the Family of Human Ubiquitin Interacting Motifs.
Acs Chem.Biol., 17, 2022
6YXY
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BU of 6yxy by Molmil
State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
分子名称: 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
登録日2020-05-04
公開日2020-10-14
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
6QC6
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BU of 6qc6 by Molmil
Ovine respiratory complex I FRC open class 1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
著者Letts, J.A, Sazanov, L.A.
登録日2018-12-27
公開日2019-08-21
最終更新日2019-10-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
8A5X
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BU of 8a5x by Molmil
Crystal structure of phosphatidyl inositol 4-kinase II beta in complex with MM1373
分子名称: 4-azanyl-7-[3-(hydroxymethyl)phenyl]quinazoline-6-carboxamide, Phosphatidylinositol 4-kinase type 2-beta,Endolysin
著者Klima, M, Boura, E.
登録日2022-06-16
公開日2022-10-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold.
Bioorg.Med.Chem.Lett., 76, 2022
1F9H
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BU of 1f9h by Molmil
CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF E. COLI HPPK(R92A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.50 ANGSTROM RESOLUTION
分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION, ...
著者Blaszczyk, J, Ji, X.
登録日2000-07-10
公開日2003-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies
Biochemistry, 42, 2003
8BCQ
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BU of 8bcq by Molmil
N-terminal domain of Plasmodium berghei glutamyl-tRNA synthetase (native crystal structure)
分子名称: GLYCEROL, Glutamate--tRNA ligase, SULFATE ION
著者Benas, P, Jaramillo Ponce, J.R, Frugier, M, Sauter, C.
登録日2022-10-17
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Solution X-ray scattering highlights discrepancies in Plasmodium multi-aminoacyl-tRNA synthetase complexes.
Protein Sci., 32, 2023
8BHD
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BU of 8bhd by Molmil
N-terminal domain of Plasmodium berghei glutamyl-tRNA synthetase (Tbxo4 derivative crystal structure)
分子名称: GLYCEROL, Glutamate--tRNA ligase, SULFATE ION, ...
著者Benas, P, Jaramillo Ponce, J.R, Legrand, P, Frugier, M, Sauter, C.
登録日2022-10-31
公開日2023-01-25
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Solution X-ray scattering highlights discrepancies in Plasmodium multi-aminoacyl-tRNA synthetase complexes.
Protein Sci., 32, 2023
3UXP
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BU of 3uxp by Molmil
Co-crystal Structure of Rat DNA polymerase beta Mutator I260Q: Enzyme-DNA-ddTTP
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA 5'-D(P*AP*CP*TP*CP*AP*CP*AP*TP*A)-3', DNA 5'-D(P*AP*TP*GP*TP*GP*AP*G)-3', ...
著者Gridley, C.L, Jaeger, J.
登録日2011-12-05
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.723 Å)
主引用文献Structural Changes in the Hydrophobic Hinge Region Adversely Affect the Activity and Fidelity of the I260Q Mutator DNA Polymerase beta.
Biochemistry, 52, 2013
8ASI
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BU of 8asi by Molmil
Four subunit cytochrome b-c1 complex from Rhodobacter sphaeroides in native nanodiscs - consensus refinement in the b-b conformation
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Cytochrome b, Cytochrome b-c1 subunit IV, ...
著者Swainsbury, D.J.K, Hawkings, F.R, Martin, E.C, Musial, S, Salisbury, J.H, Jackson, P.J, Farmer, D.A, Johnson, M.P, Siebert, C.A, Hitchcock, A, Hunter, C.N.
登録日2022-08-19
公開日2023-03-15
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM structure of the four-subunit Rhodobacter sphaeroides cytochrome bc 1 complex in styrene maleic acid nanodiscs.
Proc.Natl.Acad.Sci.USA, 120, 2023
3UXN
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BU of 3uxn by Molmil
Crystal Structure of Rat DNA Polymerase Beta, Wild Type Apoenzyme
分子名称: DNA polymerase beta
著者Gridley, C.L, Firbank, S, Jaeger, J.
登録日2011-12-05
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Changes in the Hydrophobic Hinge Region Adversely Affect the Activity and Fidelity of the I260Q Mutator DNA Polymerase beta.
Biochemistry, 52, 2013

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