Ovine respiratory complex I FRC open class 1

This is a large structure.

Summary for 6QC6

Related6qbx 6qc3 6qc2 6qc4 6q9d 6q9b 6q9e 6qa9 6qc5
EMDB information4493 4495 4494 4496 4480 4479 4481 4482 4497 4498
DescriptorNADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial, NADH:ubiquinone oxidoreductase core subunit S1, ... (53 entities in total)
Functional Keywordscomplex i, cellular respiration, mitochondria, electron transport
Biological sourceOvis aries (Sheep)
Total number of polymer chains45
Total molecular weight978996.21
Letts, J.A.,Sazanov, L.A. (deposition date: 2018-12-27, release date: 2019-08-21, Last modification date: 2019-10-02)
Primary citation
Letts, J.A.,Fiedorczuk, K.,Degliesposti, G.,Skehel, M.,Sazanov, L.A.
Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75:1131-1146.e6, 2019
PubMed: 31492636 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2019.07.022
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers6 0.1% 1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report