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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6QC6

Ovine respiratory complex I FRC open class 1

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
4L0005739cellular_componentmitochondrion
4L0005743cellular_componentmitochondrial inner membrane
4L0005747cellular_componentmitochondrial respiratory chain complex I
4L0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
4L0016020cellular_componentmembrane
4L0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
4L0042773biological_processATP synthesis coupled electron transport
4L0055085biological_processtransmembrane transport
4L0070469cellular_componentrespirasome
A30005743cellular_componentmitochondrial inner membrane
A30005747cellular_componentmitochondrial respiratory chain complex I
A50022904biological_processrespiratory electron transport chain
A60005739cellular_componentmitochondrion
A60005743cellular_componentmitochondrial inner membrane
A60005747cellular_componentmitochondrial respiratory chain complex I
A60006979biological_processresponse to oxidative stress
A60016020cellular_componentmembrane
A60031966cellular_componentmitochondrial membrane
A60032981biological_processmitochondrial respiratory chain complex I assembly
A60070469cellular_componentrespirasome
A70005743cellular_componentmitochondrial inner membrane
A70005747cellular_componentmitochondrial respiratory chain complex I
A70006120biological_processmitochondrial electron transport, NADH to ubiquinone
A70016020cellular_componentmembrane
A70042773biological_processATP synthesis coupled electron transport
A80006120biological_processmitochondrial electron transport, NADH to ubiquinone
AA0006633biological_processfatty acid biosynthetic process
AB0006633biological_processfatty acid biosynthetic process
AJ0005747cellular_componentmitochondrial respiratory chain complex I
AJ0006120biological_processmitochondrial electron transport, NADH to ubiquinone
AK0032981biological_processmitochondrial respiratory chain complex I assembly
AL0016020cellular_componentmembrane
AL0032981biological_processmitochondrial respiratory chain complex I assembly
B10005739cellular_componentmitochondrion
B10005743cellular_componentmitochondrial inner membrane
B10005747cellular_componentmitochondrial respiratory chain complex I
B10016020cellular_componentmembrane
B20005743cellular_componentmitochondrial inner membrane
B20005747cellular_componentmitochondrial respiratory chain complex I
B30005739cellular_componentmitochondrion
B30022900biological_processelectron transport chain
B40005739cellular_componentmitochondrion
B40005743cellular_componentmitochondrial inner membrane
B40005747cellular_componentmitochondrial respiratory chain complex I
B40016020cellular_componentmembrane
B60005743cellular_componentmitochondrial inner membrane
B60005747cellular_componentmitochondrial respiratory chain complex I
B60006120biological_processmitochondrial electron transport, NADH to ubiquinone
B60016020cellular_componentmembrane
B60042775biological_processmitochondrial ATP synthesis coupled electron transport
B70005739cellular_componentmitochondrion
B80005739cellular_componentmitochondrion
B80005747cellular_componentmitochondrial respiratory chain complex I
B80006120biological_processmitochondrial electron transport, NADH to ubiquinone
B90006120biological_processmitochondrial electron transport, NADH to ubiquinone
C10005739cellular_componentmitochondrion
C10005747cellular_componentmitochondrial respiratory chain complex I
C20005737cellular_componentcytoplasm
C20005739cellular_componentmitochondrion
C20005743cellular_componentmitochondrial inner membrane
C20005747cellular_componentmitochondrial respiratory chain complex I
C20006120biological_processmitochondrial electron transport, NADH to ubiquinone
C20016020cellular_componentmembrane
C20032981biological_processmitochondrial respiratory chain complex I assembly
C20070469cellular_componentrespirasome
D10003954molecular_functionNADH dehydrogenase activity
D10005739cellular_componentmitochondrion
D10005743cellular_componentmitochondrial inner membrane
D10005747cellular_componentmitochondrial respiratory chain complex I
D10006120biological_processmitochondrial electron transport, NADH to ubiquinone
D10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D10009060biological_processaerobic respiration
D10016020cellular_componentmembrane
D10031966cellular_componentmitochondrial membrane
D10032981biological_processmitochondrial respiratory chain complex I assembly
D10055085biological_processtransmembrane transport
D10070469cellular_componentrespirasome
D20005739cellular_componentmitochondrion
D20005743cellular_componentmitochondrial inner membrane
D20005747cellular_componentmitochondrial respiratory chain complex I
D20006120biological_processmitochondrial electron transport, NADH to ubiquinone
D20008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D20016020cellular_componentmembrane
D20032981biological_processmitochondrial respiratory chain complex I assembly
D20055085biological_processtransmembrane transport
D20070469cellular_componentrespirasome
D20072593biological_processreactive oxygen species metabolic process
D30005739cellular_componentmitochondrion
D30005743cellular_componentmitochondrial inner membrane
D30005747cellular_componentmitochondrial respiratory chain complex I
D30006120biological_processmitochondrial electron transport, NADH to ubiquinone
D30008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D30016020cellular_componentmembrane
D30055085biological_processtransmembrane transport
D30070469cellular_componentrespirasome
D40003954molecular_functionNADH dehydrogenase activity
D40005739cellular_componentmitochondrion
D40005743cellular_componentmitochondrial inner membrane
D40005747cellular_componentmitochondrial respiratory chain complex I
D40006120biological_processmitochondrial electron transport, NADH to ubiquinone
D40008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D40009060biological_processaerobic respiration
D40015990biological_processelectron transport coupled proton transport
D40016020cellular_componentmembrane
D40032981biological_processmitochondrial respiratory chain complex I assembly
D40042773biological_processATP synthesis coupled electron transport
D40045271cellular_componentrespiratory chain complex I
D40048039molecular_functionubiquinone binding
D40055085biological_processtransmembrane transport
D40070469cellular_componentrespirasome
D50003954molecular_functionNADH dehydrogenase activity
D50005739cellular_componentmitochondrion
D50005743cellular_componentmitochondrial inner membrane
D50005747cellular_componentmitochondrial respiratory chain complex I
D50006120biological_processmitochondrial electron transport, NADH to ubiquinone
D50008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D50015990biological_processelectron transport coupled proton transport
D50016020cellular_componentmembrane
D50032981biological_processmitochondrial respiratory chain complex I assembly
D50042773biological_processATP synthesis coupled electron transport
D50055085biological_processtransmembrane transport
D50070469cellular_componentrespirasome
D60005739cellular_componentmitochondrion
D60005743cellular_componentmitochondrial inner membrane
D60005747cellular_componentmitochondrial respiratory chain complex I
D60006120biological_processmitochondrial electron transport, NADH to ubiquinone
D60008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D60016020cellular_componentmembrane
D60032981biological_processmitochondrial respiratory chain complex I assembly
D60055085biological_processtransmembrane transport
D60070469cellular_componentrespirasome
S10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S10016020cellular_componentmembrane
S10016491molecular_functionoxidoreductase activity
S10016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S10042773biological_processATP synthesis coupled electron transport
S10051536molecular_functioniron-sulfur cluster binding
S20016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S20048038molecular_functionquinone binding
S20051287molecular_functionNAD binding
S30008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S30016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S40022900biological_processelectron transport chain
S60005747cellular_componentmitochondrial respiratory chain complex I
S60006120biological_processmitochondrial electron transport, NADH to ubiquinone
S70008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S70048038molecular_functionquinone binding
S70051536molecular_functioniron-sulfur cluster binding
S70051539molecular_function4 iron, 4 sulfur cluster binding
S80016020cellular_componentmembrane
S80016651molecular_functionoxidoreductase activity, acting on NAD(P)H
S80051539molecular_function4 iron, 4 sulfur cluster binding
V10003954molecular_functionNADH dehydrogenase activity
V10005739cellular_componentmitochondrion
V10005743cellular_componentmitochondrial inner membrane
V10005747cellular_componentmitochondrial respiratory chain complex I
V10006120biological_processmitochondrial electron transport, NADH to ubiquinone
V10008137molecular_functionNADH dehydrogenase (ubiquinone) activity
V10010181molecular_functionFMN binding
V10016020cellular_componentmembrane
V10045271cellular_componentrespiratory chain complex I
V10046872molecular_functionmetal ion binding
V10051287molecular_functionNAD binding
V10051536molecular_functioniron-sulfur cluster binding
V10051539molecular_function4 iron, 4 sulfur cluster binding
V10055085biological_processtransmembrane transport
V10070469cellular_componentrespirasome
V20016491molecular_functionoxidoreductase activity
V30005739cellular_componentmitochondrion
V30005747cellular_componentmitochondrial respiratory chain complex I
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue SF4 V1 500
ChainResidue
V1PRO203
V1SER358
V1CYS359
V1GLN361
V1CYS362
V1CYS365
V1THR403
V1CYS405
site_idAC2
Number of Residues15
Detailsbinding site for residue FMN V1 501
ChainResidue
V1ARG68
V1GLY69
V1ALA71
V1LYS78
V1ASN96
V1ASP98
V1GLU101
V1TYR184
V1GLY187
V1GLU188
V1GLU189
V1VAL222
V1ASN224
V1THR227
V1GLY67
site_idAC3
Number of Residues8
Detailsbinding site for residue FES V2 300
ChainResidue
V1PRO102
V2CYS103
V2THR105
V2CYS108
V2CYS144
V2ALA147
V2CYS148
V2MET153
site_idAC4
Number of Residues8
Detailsbinding site for residue SF4 S1 801
ChainResidue
S1HIS101
S1CYS105
S1CYS108
S1GLN110
S1CYS114
S1GLN117
S1VAL205
S1GLY206
site_idAC5
Number of Residues7
Detailsbinding site for residue SF4 S1 802
ChainResidue
S1CYS153
S1ILE154
S1CYS156
S1THR157
S1CYS159
S1CYS203
S1VAL205
site_idAC6
Number of Residues6
Detailsbinding site for residue FES S1 803
ChainResidue
S1CYS41
S1GLY50
S1CYS52
S1ARG53
S1CYS55
S1CYS69
site_idAC7
Number of Residues10
Detailsbinding site for residue SF4 S7 300
ChainResidue
S2ARG105
S7ALA53
S7CYS54
S7CYS55
S7GLY90
S7GLY117
S7SER118
S7CYS119
S7CYS149
S7PRO150
site_idAC8
Number of Residues10
Detailsbinding site for residue SF4 S8 201
ChainResidue
S8HIS65
S8CYS87
S8PRO88
S8ILE92
S8CYS116
S8ILE117
S8TYR118
S8CYS119
S8CYS122
S8GLU133
site_idAC9
Number of Residues9
Detailsbinding site for residue SF4 S8 202
ChainResidue
S8CYS77
S8ILE78
S8ALA79
S8CYS80
S8LYS81
S8CYS83
S8TYR109
S8CYS126
S8ILE131
site_idAD1
Number of Residues5
Detailsbinding site for residue ZN S6 300
ChainResidue
S6CYS59
S6HIS68
S6VAL71
S6CYS84
S6CYS87
site_idAD2
Number of Residues19
Detailsbinding site for residue NDP A9 401
ChainResidue
A9HIS134
A9TYR145
A9LYS149
A9PRO168
A9ALA169
A9ILE171
A9GLY25
A9ALA26
A9THR27
A9GLY28
A9PHE29
A9ARG50
A9CYS51
A9TRP73
A9VAL95
A9GLY96
A9ARG97
A9PHE104
A9ILE132
site_idAD3
Number of Residues8
Detailsbinding site for residue ZMP AA 101
ChainResidue
A6LYS28
A6ARG32
A6TRP38
A6ASN69
A6ALA70
A6VAL72
AAASP43
AASER44
site_idAD4
Number of Residues10
Detailsbinding site for residue 3PE D1 501
ChainResidue
AMTHR143
D1MET98
D1ASN99
D1LEU100
D3LEU3
D6GLY38
D6LEU45
D6ASN46
D6GLY49
D6LEU54
site_idAD5
Number of Residues10
Detailsbinding site for residue CDL D5 901
ChainResidue
B5LEU22
D4PRO353
D4LEU354
D4ALA357
D5ASN23
D5GLN116
D5LYS119
D5TYR120
D5LEU123
D5MET150
site_idAD6
Number of Residues11
Detailsbinding site for residue 3PE D4 501
ChainResidue
D2LEU288
D2TYR291
D4LEU147
D4TYR148
D4PHE151
D4TYR152
D5LEU562
D5ILE566
D5SER567
S2TYR14
S2MET19
site_idAD7
Number of Residues6
Detailsbinding site for residue PC1 D4 502
ChainResidue
AKGLU130
AKTRP132
D2ILE276
D2ILE277
D4TYR166
D4SER191
site_idAD8
Number of Residues10
Detailsbinding site for residue ZMP AB 101
ChainResidue
ABASP43
ABSER44
ABLEU45
B9HIS11
B9GLN12
B9ARG46
B9PHE47
B9HIS50
B9LYS51
B9GLU69
site_idAD9
Number of Residues10
Detailsbinding site for residue 3PE B8 201
ChainResidue
B8ASN87
B8ARG88
B8ASP90
D4LEU405
D5LEU169
D5GLN170
D5TYR174
D5HIS534
D5THR537
D5ASN541
Functional Information from PROSITE/UniProt
site_idPS00198
Number of Residues12
Details4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP
ChainResidueDetails
S8CYS77-PRO88
S8CYS116-PRO127
site_idPS00641
Number of Residues18
DetailsCOMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC
ChainResidueDetails
S1PRO38-CYS55
site_idPS00642
Number of Residues13
DetailsCOMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ
ChainResidueDetails
S1CYS105-GLN117
site_idPS00643
Number of Residues11
DetailsCOMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF
ChainResidueDetails
S1ARG152-PHE162
site_idPS00667
Number of Residues16
DetailsCOMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDAIKLFiKE
ChainResidueDetails
D1GLY44-GLU59
site_idPS00668
Number of Residues14
DetailsCOMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G
ChainResidueDetails
D1PRO197-GLY210
site_idPS01099
Number of Residues19
DetailsCOMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP
ChainResidueDetails
V2ASP134-PRO152
site_idPS01150
Number of Residues17
DetailsCOMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP
ChainResidueDetails
S7GLY135-PRO151
site_idPS00542
Number of Residues22
DetailsCOMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL
ChainResidueDetails
S3GLU131-LEU152
site_idPS00644
Number of Residues16
DetailsCOMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES
ChainResidueDetails
V1GLY180-SER195
site_idPS00645
Number of Residues12
DetailsCOMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG
ChainResidueDetails
V1GLU357-GLY368
site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM
ChainResidueDetails
ABASP39-MET54
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI
ChainResidueDetails
ABASP64-ILE76
site_idPS00535
Number of Residues12
DetailsCOMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK
ChainResidueDetails
S2LEU83-LYS94
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues220
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
D2PRO3-SER23
D2HIS25-MET45
D2SER67-MET87
D2MET96-PRO116
D2ILE122-LEU142
D2ILE145-GLY165
D2ILE178-PRO198
D2MET200-MET220
D2ALA237-LEU257
D2ASP274-MET294
D2LEU325-ILE345
D5MET366-LEU386
D5LEU413-GLY433
D5LEU457-ILE477
D5TYR485-SER505
D5GLY582-LEU602

218500

PDB entries from 2024-04-17

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