Ovine respiratory supercomplex I+III2 open class 2

This is a large structure.

Summary for 6QC2

Related6QBX 6Q9D 6Q9B 6Q9E 6QA9
EMDB information4493 4480 4479 4481 4482 4494
DescriptorNADH-ubiquinone oxidoreductase chain 3, NADH-ubiquinone oxidoreductase chain 1, NADH-ubiquinone oxidoreductase chain 6, ... (65 entities in total)
Functional Keywordssupercomplex, cellular respiration, mitochondria, electron transport
Biological sourceOvis aries (Sheep)
Total number of polymer chains65
Total molecular weight1454085.71
Letts, J.A.,Sazanov, L.A. (deposition date: 2018-12-26, release date: 2019-08-21, Last modification date: 2019-10-02)
Primary citation
Letts, J.A.,Fiedorczuk, K.,Degliesposti, G.,Skehel, M.,Sazanov, L.A.
Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75:1131-1146.e6, 2019
PubMed: 31492636 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2019.07.022
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers7 0.1% 1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report