6QC2

Ovine respiratory supercomplex I+III2 open class 2

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	D3	NADH-ubiquinone oxidoreductase chain 3	polymer	115	13106.5	1	UniProt (O78753) Pfam (PF00507) In PDB	Ovis aries (Sheep)	NADH dehydrogenase subunit 3
2	D1	NADH-ubiquinone oxidoreductase chain 1	polymer	318	35884.9	1	UniProt (O78747) Pfam (PF00146) In PDB	Ovis aries (Sheep)	NADH dehydrogenase subunit 1
3	D6	NADH-ubiquinone oxidoreductase chain 6	polymer	175	19126.6	1	UniProt (O78757) Pfam (PF00499) In PDB	Ovis aries (Sheep)	NADH dehydrogenase subunit 6
4	4L	NADH-ubiquinone oxidoreductase chain 4L	polymer	98	10840.2	1	UniProt (O78754) Pfam (PF00420) In PDB	Ovis aries (Sheep)	NADH dehydrogenase subunit 4L
5	D5	NADH-ubiquinone oxidoreductase chain 5	polymer	606	68410.9	1	UniProt (O78756) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) In PDB	Ovis aries (Sheep)	NADH dehydrogenase subunit 5
6	D4	NADH-ubiquinone oxidoreductase chain 4	polymer	459	52058.7	1	UniProt (O78755) Pfam (PF01059) Pfam (PF00361) In PDB	Ovis aries (Sheep)	NADH dehydrogenase subunit 4
7	D2	NADH-ubiquinone oxidoreductase chain 2	polymer	347	39149.8	1	UniProt (O78748) Pfam (PF00361) Pfam (PF06444) In PDB	Ovis aries (Sheep)	NADH dehydrogenase subunit 2
8	AK	NDUFA11	polymer	140	14610.8	1	UniProt (W5PAR2) In PDB	Ovis aries (Sheep)
9	B5	NADH:ubiquinone oxidoreductase subunit B5	polymer	143	16714.4	1	UniProt (W5QHN8) In PDB	Ovis aries (Sheep)
10	AB, AA	Acyl carrier protein	polymer	88	10119.5	2	UniProt (W5NQT7) Pfam (PF00550) In PDB	Ovis aries (Sheep)
11	A8	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8	polymer	171	20008.0	1	UniProt (W5PYA5) In PDB	Ovis aries (Sheep)
12	BJ	NDUFB10	polymer	175	20880.8	1		Ovis aries	NDUFA10
13	AJ	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial	polymer	320	36803.8	1	UniProt (W5QBF5) In PDB	Ovis aries (Sheep)
14	S5	NADH:ubiquinone oxidoreductase subunit S5	polymer	105	12474.4	1	UniProt (W5QFF9) In PDB	Ovis aries (Sheep)
15	A3	NADH:ubiquinone oxidoreductase subunit A3	polymer	83	9194.7	1	UniProt (W5NYM7) In PDB	Ovis aries (Sheep)
16	B3	NADH:ubiquinone oxidoreductase subunit B3	polymer	97	11015.5	1	UniProt (W5Q5T4) In PDB	Ovis aries (Sheep)
17	C2	NADH dehydrogenase [ubiquinone] 1 subunit C2	polymer	120	14231.4	1	UniProt (W5P9Q8) Pfam (PF06374) In PDB	Ovis aries (Sheep)
18	B4	NADH:ubiquinone oxidoreductase subunit B4	polymer	128	14976.0	1	UniProt (W5QF73) Pfam (PF07225) In PDB	Ovis aries (Sheep)
19	AM	NDUFA13	polymer	143	16635.3	1		Ovis aries	MT-ND3
20	B6	NDUFB6	polymer	127	15433.9	1	UniProt (W5PZE3) Pfam (PF09782) In PDB	Ovis aries (Sheep)
21	B7	NADH:ubiquinone oxidoreductase subunit B7	polymer	119	14645.7	1	UniProt (W5P5V3) In PDB	Ovis aries (Sheep)
22	B9	NADH:ubiquinone oxidoreductase subunit B9	polymer	178	21648.7	1	UniProt (W5PGA3) In PDB	Ovis aries (Sheep)
23	B2	NADH:ubiquinone oxidoreductase subunit B2	polymer	72	8500.3	1	UniProt (W5PVD7) In PDB	Ovis aries (Sheep)
24	B8	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	polymer	158	18818.1	1	UniProt (W5Q1B0) Pfam (PF05821) In PDB	Ovis aries (Sheep)	Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit
25	BK	NDUFB11	polymer	125	14455.0	1	UniProt (W5PWF1) In PDB	Ovis aries (Sheep)
26	C1	NDUFC1	polymer	49	5808.6	1		Ovis aries	NDUFC1
27	B1	NDUFB1	polymer	57	6930.1	1	UniProt (W5QG39) Pfam (PF08040) In PDB	Ovis aries (Sheep)
28	A1	NDUFA1	polymer	70	8211.5	1		Ovis aries	NDUFA1
29	a1, a3	UQCRC1	polymer	446	49385.4	2		Ovis aries	UQCRC1
30	a2, a4	Ubiquinol-cytochrome c reductase core protein 2	polymer	439	46655.5	2	UniProt (W5Q0F9) In PDB	Ovis aries (Sheep)
31	b1, b2	Cytochrome b	polymer	379	42877.8	2	UniProt (P24959) Pfam (PF00033) Pfam (PF00032) In PDB	Ovis aries (Sheep)	Complex III subunit 3,Complex III subunit III,Cytochrome b-c1 complex subunit 3,Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
32	c1, c2	Cytochrome c1	polymer	240	27322.3	2	UniProt (W5Q0A9) In PDB	Ovis aries (Sheep)
33	f1, f2	Cytochrome b-c1 complex subunit Rieske, mitochondrial	polymer	196	21654.6	2	UniProt (W5P2X9) In PDB	Ovis aries (Sheep)
34	d1, d2	UQCRB	polymer	110	13432.3	2		Ovis aries	UQCRB
35	q1, q2	Ubiquinol-cytochrome c reductase complex III subunit VII	polymer	81	9606.1	2	UniProt (W5PUP9) Pfam (PF02939) In PDB	Ovis aries (Sheep)
36	h1, h2	UQCRQH	polymer	78	9223.1	2		Ovis aries	UQCRH
37	x1, x2	UQCRFS1N	polymer	78	6656.2	2		Ovis aries	UQCRFS1N
38	i1, i2	Ubiquinol-cytochrome c reductase, complex III subunit X	polymer	63	7310.4	2	UniProt (W5P6B2) In PDB	Ovis aries (Sheep)
39	V1	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	polymer	445	48678.3	1	UniProt (W5PUX0) Pfam (PF01512) Pfam (PF10531) Pfam (PF10589) In PDB	Ovis aries (Sheep)
40	V2	NDUFV2	polymer	217	23840.4	1	UniProt (W5NRY1) Pfam (PF01257) In PDB	Ovis aries (Sheep)
41	S1	NADH:ubiquinone oxidoreductase core subunit S1	polymer	704	77031.2	1	UniProt (W5QB34) In PDB	Ovis aries (Sheep)
42	S2	NDUFS2	polymer	430	49193.3	1		Ovis aries	NDUFS2
43	S3	NADH:ubiquinone oxidoreductase core subunit S3	polymer	228	26441.8	1	UniProt (W5PB27) Pfam (PF00329) In PDB	Ovis aries (Sheep)
44	S7	NDUFS7	polymer	179	20104.5	1		Ovis aries	NDUFS7
45	S8	NDUFS8	polymer	176	20219.9	1		Ovis aries	NDUFS8
46	V3	NDUFV3	polymer	75	8423.3	1		Ovis aries	NDUFV3
47	S6	NDUFS6	polymer	96	10651.8	1		Ovis aries	NDUFS6
48	S4	NADH:ubiquinone oxidoreductase subunit S4	polymer	133	15375.3	1	UniProt (W5PE07) Pfam (PF04800) In PDB	Ovis aries (Sheep)
49	A9	NADH:ubiquinone oxidoreductase subunit A9	polymer	338	38660.5	1	UniProt (W5PI58) In PDB	Ovis aries (Sheep)
50	A2	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	polymer	98	10966.6	1	UniProt (W5QAH8) In PDB	Ovis aries (Sheep)
51	A5	NDUFA5	polymer	115	13156.3	1	UniProt (W5PNX7) In PDB	Ovis aries (Sheep)
52	A6	NADH:ubiquinone oxidoreductase subunit A6	polymer	127	14923.2	1	UniProt (W5QC06) Pfam (PF13233) In PDB	Ovis aries (Sheep)
53	A7	NDUFA7	polymer	112	12399.2	1	UniProt (W5P0I2) Pfam (PF07347) In PDB	Ovis aries (Sheep)
54	AL	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	polymer	145	17115.5	1	UniProt (B9VGZ9) In PDB	Ovis aries (Sheep)
55	f2, D1, D5, D4, b2	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE	non-polymer		748.1	5	Chemie (3PE)
56	D4	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		790.1	1	Chemie (PC1)
57	AA, AB	S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate	non-polymer		568.7	2	Chemie (ZMP)
58	b1, b2	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	4	Chemie (HEM)
59	c2, c1	HEME C	non-polymer		618.5	2	Chemie (HEC)
60	f2, V2, S1, f1	FE2/S2 (INORGANIC) CLUSTER	non-polymer		175.8	4	Chemie (FES)
61	b2, c2	CARDIOLIPIN	non-polymer		1464.0	3	Chemie (CDL)
62	V1, S1, S7, S8	IRON/SULFUR CLUSTER	non-polymer		351.6	6	Chemie (SF4)
63	V1	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	1	Chemie (FMN)
64	S6	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
65	A9	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	1	Chemie (NDP)

Sequence modifications

B1: 1 - 57 (UniProt: W5QG39)

PDB	External Database	Details
Val 16	Gly 17	conflict
Ala 35	Thr 36	conflict
Arg 38	Trp 39	conflict

Contents of the asymmetric unit

Polymers	Number of chains	65
	Total formula weight	1436242.5
Non-Polymers*	Number of molecules	30
	Total formula weight	17843.3
All*	Total formula weight	1454085.7

*Water molecules are not included.