8P2W

Structure of human SIT1 (focussed map / refinement)

Summary for 8P2W

• Entry DOI: 10.2210/pdb8p2w/pdb
• EMDB information: 17377
• Descriptor: Processed angiotensin-converting enzyme 2, Sodium- and chloride-dependent transporter XTRP3, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: covid-19 receptor, amino acid transport, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 165244.24

Authors

Li, H.Z.,Pike, A.C.W.,Chi, G.,Hansen, J.S.,Lee, S.G.,Rodstrom, K.E.J.,Bushell, S.R.,Speedman, D.,Evans, A.,Wang, D.,He, D.,Shrestha, L.,Nasrallah, C.,Chalk, R.,Moreira, T.,MacLean, E.M.,Marsden, B.,Bountra, C.,Burgess-Brown, N.A.,Dafforn, T.R.,Carpenter, E.P.,Sauer, D.B. (deposition date: 2023-05-16, release date: 2024-06-12)

• Primary citation: Li, H.Z.,Pike, A.C.W.,Chi, G.,Hansen, J.S.,Lee, S.G.,Rodstrom, K.E.J.,Bushell, S.R.,Speedman, D.,Evans, A.,Wang, D.,He, D.,Shrestha, L.,Nasrallah, C.,Burgess-Brown, N.A.,Dafforn, T.R.,Carpenter, E.P.,Sauer, D.B.; Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2; TO BE CONFIRMED,

Experimental method

ELECTRON MICROSCOPY (3.76 Å)