8B7W

Complex IL-17A/anti-IL-17A-76

Summary for 8B7W

Entry DOI	10.2210/pdb8b7w/pdb
Descriptor	anti-IL-17A-76, Interleukin-17A, GLYCEROL, ... (6 entities in total)
Functional Keywords	interleukin 17a in complex with vhh domain, netakimab, crystal structure., immune system, inhibitor, immune system/inhibitor, immune system-inhibitor complex
Biological source	Lama glama More
Total number of polymer chains	2
Total formula weight	27606.14
Authors	Kostareva, O.S.,Svoeglazova, A.,Kolyadenko, I.A.,Dzhus, U.F.,Tishchenko, S.V.,Gabdulkhakov, A.G. (deposition date: 2022-10-03, release date: 2022-12-28, Last modification date: 2024-01-31)
Primary citation	Kostareva, O.,Svoeglazova, A.,Kolyadenko, I.,Nikulin, A.,Evdokimov, S.,Dzhus, U.,Gabdulkhakov, A.,Tishchenko, S. Two Epitope Regions Revealed in the Complex of IL-17A and Anti-IL-17A V H H Domain. Int J Mol Sci, 23:-, 2022 Cited by PubMed: 36499233 DOI: 10.3390/ijms232314904 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation