8B7W
Complex IL-17A/anti-IL-17A-76
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | anti-IL-17A-76 | polymer | 125 | 13261.7 | 1 | Lama glama | ||
| 2 | B (C) | Interleukin-17A | polymer | 122 | 14120.8 | 1 | UniProt (Q16552) Pfam (PF06083) | Homo sapiens (human) | IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8 |
| 3 | C (H) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (H) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | F, G (H, C) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
C: 11 - 132 (UniProt: Q16552)
| PDB | External Database | Details |
|---|---|---|
| Asp 45 | Asn 68 | engineered mutation |
| Ser 106 | Cys 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27382.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 223.6 | |
| All* | Total formula weight | 27606.1 |
