8OMU
Cryo-EM structure of rat SLC22A6 bound to alpha-ketoglutaric acid in a low occupancy state
Summary for 8OMU
| Entry DOI | 10.2210/pdb8omu/pdb |
| EMDB information | 16977 |
| Descriptor | Solute carrier family 22 member 6, Synthetic nanobody (Sybody) (2 entities in total) |
| Functional Keywords | membrane protein, transporter, metal transport |
| Biological source | Rattus norvegicus (Norway rat) More |
| Total number of polymer chains | 2 |
| Total formula weight | 76633.38 |
| Authors | Parker, J.L.,Kato, T.,Newstead, S. (deposition date: 2023-03-31, release date: 2023-07-19, Last modification date: 2023-11-22) |
| Primary citation | Parker, J.L.,Kato, T.,Kuteyi, G.,Sitsel, O.,Newstead, S. Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1. Nat.Struct.Mol.Biol., 30:1786-1793, 2023 Cited by PubMed: 37482561DOI: 10.1038/s41594-023-01039-y PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.43 Å) |
Structure validation
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