3DC2
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2ZLF
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![BU of 2zlf by Molmil](/molmil-images/mine/2zlf) | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase | 分子名称: | FTLDADF, Ribonucleoside-diphosphate reductase large chain 1 | 著者 | Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. | 登録日 | 2008-04-09 | 公開日 | 2008-08-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore J.Med.Chem., 51, 2008
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3DCT
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![BU of 3dct by Molmil](/molmil-images/mine/3dct) | FXR with SRC1 and GW4064 | 分子名称: | 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid, Bile acid receptor, Nuclear receptor coactivator 1 | 著者 | Williams, S.P, Madauss, K.P. | 登録日 | 2008-06-04 | 公開日 | 2008-08-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064. Bioorg.Med.Chem.Lett., 18, 2008
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2ZCY
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![BU of 2zcy by Molmil](/molmil-images/mine/2zcy) | yeast 20S proteasome:syringolin A-complex | 分子名称: | (2S)-2-[[(2S)-1-[[(5S,8S,9E)-2,7-dioxo-5-propan-2-yl-1,6-diazacyclododeca-3,9-dien-8-yl]amino]-3-methyl-1-oxo-butan-2-yl]carbamoylamino]-3-methyl-butanoic acid, Proteasome component C1, Proteasome component C11, ... | 著者 | Groll, M, Dudler, R, Kaiser, M. | 登録日 | 2007-11-15 | 公開日 | 2008-04-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism Nature, 452, 2008
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3DAR
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4J50
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![BU of 4j50 by Molmil](/molmil-images/mine/4j50) | Crystal Structure of an Expanded RNA CAG Repeat | 分子名称: | PHOSPHATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*AP*GP*CP*AP*GP*CP*AP*GP*GP*UP*CP*C)-3') | 著者 | Park, H, Disney, M.D. | 登録日 | 2013-02-07 | 公開日 | 2013-02-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A dynamic structural model of expanded RNA CAG repeats: a refined X-ray structure and computational investigations using molecular dynamics and umbrella sampling simulations. J.Am.Chem.Soc., 135, 2013
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3DDN
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5D4E
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4FZC
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![BU of 4fzc by Molmil](/molmil-images/mine/4fzc) | 20S yeast proteasome in complex with cepafungin I | 分子名称: | Cepafungin I, Proteasome component C1, Proteasome component C11, ... | 著者 | Stein, M, Beck, P, Kaiser, M, Dudler, R, Becker, C.F.W, Groll, M. | 登録日 | 2012-07-06 | 公開日 | 2012-10-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor. Proc.Natl.Acad.Sci.USA, 109, 2012
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5DGT
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5D9G
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![BU of 5d9g by Molmil](/molmil-images/mine/5d9g) | Crystal structure of TIPRL, TOR signaling pathway regulator-like, in complex with peptide | 分子名称: | CHLORIDE ION, NICKEL (II) ION, PHOSPHATE ION, ... | 著者 | Scorsato, V, Sandy, J, Brandao-Neto, J, Pereira, H.M, Smetana, J.H.C, Aparicio, R. | 登録日 | 2015-08-18 | 公開日 | 2016-08-10 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of the human Tip41 orthologue, TIPRL, reveals a novel fold and a binding site for the PP2Ac C-terminus. Sci Rep, 6, 2016
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5US9
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4KF0
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![BU of 4kf0 by Molmil](/molmil-images/mine/4kf0) | Structure of the A82F P450 BM3 heme domain | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Leys, D. | 登録日 | 2013-04-26 | 公開日 | 2013-07-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288, 2013
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3DCU
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![BU of 3dcu by Molmil](/molmil-images/mine/3dcu) | FXR with SRC1 and GSK8062 | 分子名称: | 6-(4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)naphthalene-1-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1 | 著者 | Williams, S.P, Madauss, K.P. | 登録日 | 2008-06-04 | 公開日 | 2008-08-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064. Bioorg.Med.Chem.Lett., 18, 2008
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4KIW
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![BU of 4kiw by Molmil](/molmil-images/mine/4kiw) | Design and structural analysis of aromatic inhibitors of type II dehydroquinate dehydratase from Mycobacterium tuberculosis - compound 49e [5-[(3-nitrobenzyl)amino]benzene-1,3-dicarboxylic acid] | 分子名称: | 3-dehydroquinate dehydratase, 5-[(3-nitrobenzyl)amino]benzene-1,3-dicarboxylic acid | 著者 | Dias, M.V.B, Howard, N.G, Blundell, T.L, Abell, C. | 登録日 | 2013-05-02 | 公開日 | 2014-05-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Design and Structural Analysis of Aromatic Inhibitors of Type II Dehydroquinase from Mycobacterium tuberculosis. Chemmedchem, 10, 2015
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4GGF
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![BU of 4ggf by Molmil](/molmil-images/mine/4ggf) | Crystal structure of Mn2+ bound calprotectin | 分子名称: | CALCIUM ION, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Damo, S.M, Fritz, G. | 登録日 | 2012-08-06 | 公開日 | 2013-02-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens. Proc.Natl.Acad.Sci.USA, 110, 2013
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4KPE
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![BU of 4kpe by Molmil](/molmil-images/mine/4kpe) | Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate | 分子名称: | (7aR,8R)-8-amino-4-cyclopropyl-12-fluoro-1-oxo-4,7,7a,8,9,10-hexahydro-1H-pyrrolo[1',2':1,7]azepino[2,3-h]quinoline-2-carboxylic acid, DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, ... | 著者 | Laponogov, I, Pan, X.-S, Vesekov, D.A, Cirz, R.T, Wagman, A.S, Moser, H.E, Fisher, L.M, Sanderson, M.R. | 登録日 | 2013-05-13 | 公開日 | 2014-11-26 | 最終更新日 | 2020-01-29 | 実験手法 | X-RAY DIFFRACTION (3.43 Å) | 主引用文献 | Exploring the active site of the Streptococcus pneumoniae topoisomerase IV-DNA cleavage complex with novel 7,8-bridged fluoroquinolones. Open Biol, 6, 2016
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2XFF
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![BU of 2xff by Molmil](/molmil-images/mine/2xff) | Crystal structure of Barley Beta-Amylase complexed with acarbose | 分子名称: | 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, BETA-AMYLASE | 著者 | Rejzek, M, Stevenson, C.E.M, Southard, A.M, Stanley, D, Denyer, K, Smith, A.M, Naldrett, M.J, Lawson, D.M, Field, R.A. | 登録日 | 2010-05-28 | 公開日 | 2010-12-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.309 Å) | 主引用文献 | Chemical Genetics and Cereal Starch Metabolism: Structural Basis of the Non-Covalent and Covalent Inhibition of Barley Beta-Amylase. Mol.Biosyst., 7, 2011
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4Z3U
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![BU of 4z3u by Molmil](/molmil-images/mine/4z3u) | PRV nuclear egress complex | 分子名称: | CHLORIDE ION, SODIUM ION, UL31, ... | 著者 | Bigalke, J.M, Heldwein, E.E. | 登録日 | 2015-03-31 | 公開日 | 2015-11-11 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (2.706 Å) | 主引用文献 | Structural basis of membrane budding by the nuclear egress complex of herpesviruses. Embo J., 34, 2015
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3DAU
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5TAQ
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![BU of 5taq by Molmil](/molmil-images/mine/5taq) | Structure of rabbit RyR1 (Caffeine/ATP/Ca2+ dataset, class 3&4) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... | 著者 | Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. | 登録日 | 2016-09-10 | 公開日 | 2016-10-12 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
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5CZA
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![BU of 5cza by Molmil](/molmil-images/mine/5cza) | Yeast 20S proteasome beta5-D166N mutant | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2015-07-31 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome. Nat Commun, 7, 2016
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5SVC
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![BU of 5svc by Molmil](/molmil-images/mine/5svc) | Mechanism of ATP-Dependent Acetone Carboxylation, Acetone Carboxylase nucleotide-free structure | 分子名称: | Acetone carboxylase alpha subunit, Acetone carboxylase beta subunit, Acetone carboxylase gamma subunit, ... | 著者 | Eilers, B.J, Mus, F, Alleman, A.B, Kabasakal, B.V, Murray, J.W, Nocek, B.P, Dubois, J.L, Peters, J.W. | 登録日 | 2016-08-05 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation. Sci Rep, 7, 2017
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4ZBL
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5D4C
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