4GGF

Crystal structure of Mn2+ bound calprotectin

Summary for 4GGF

• Entry DOI: 10.2210/pdb4ggf/pdb
• Descriptor: Protein S100-A8, Protein S100-A9, CALCIUM ION, ... (7 entities in total)
• Functional Keywords: s100, ef-hand, antimicrobial protein
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P05109 P06702
• Total number of polymer chains: 8
• Total formula weight: 98047.93

Authors

Damo, S.M.,Fritz, G. (deposition date: 2012-08-06, release date: 2013-02-20, Last modification date: 2023-09-13)

• Primary citation: Damo, S.M.,Kehl-Fie, T.E.,Sugitani, N.,Holt, M.E.,Rathi, S.,Murphy, W.J.,Zhang, Y.,Betz, C.,Hench, L.,Fritz, G.,Skaar, E.P.,Chazin, W.J.; Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens.; Proc.Natl.Acad.Sci.USA, 110:3841-3846, 2013; PubMed: 23431180; DOI: 10.1073/pnas.1220341110

Experimental method

X-RAY DIFFRACTION (1.6 Å)