4GGF
Crystal structure of Mn2+ bound calprotectin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, K, S, U) | Protein S100-A8 | polymer | 93 | 10837.5 | 4 | UniProt (P05109) Pfam (PF01023) | Homo sapiens (human) | Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CFAG, Leukocyte L1 complex light chain, Migration inhibitory factor-related protein 8, MRP-8, p8, S100 calcium-binding protein A8, Urinary stone protein band A |
| 2 | B, D, F, H (C, L, T, V) | Protein S100-A9 | polymer | 114 | 13248.0 | 4 | UniProt (P06702) Pfam (PF01023) | Homo sapiens (human) | Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9 |
| 3 | BA, CA, FA, I, IA... (T, U, A, V, C...) | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) | |||
| 4 | AA, GA, J, K, R... (T, V, C, L) | MANGANESE (II) ION | non-polymer | 54.9 | 7 | Chemie (MN) | |||
| 5 | DA, EA, N, Q, X... (T, C, K, S) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 6 | HA, O, T (V, K, L) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | KA, LA, MA, NA, OA... (A, C, K, L, S...) | water | water | 18.0 | 488 | Chemie (HOH) |
Sequence modifications
A, K, S, U: 1 - 93 (UniProt: P05109)
C, L, T, V: 1 - 114 (UniProt: P06702)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | Cys 42 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | Cys 3 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 96341.7 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 1706.3 | |
| All* | Total formula weight | 98047.9 |
