PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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6DDE	Mu Opioid Receptor-Gi Protein Complex 分子名称: DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Koehl, A, Hu, H, Maeda, S, Manglik, A, Zhang, Y, Kobilka, B.K, Skiniotis, G, Weis, W.I. 登録日 2018-05-10 公開日 2018-06-13 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of the mu-opioid receptor-Giprotein complex. Nature, 558, 2018
6DQQ	Crystal structure of Haemophilus influenzae OppA complex with endogenous peptide 分子名称: ACETATE ION, ALA-ALA-ALA-ALA, Periplasmic oligopeptide-binding protein, ... 著者 Tanaka, K.J, Pinkett, H.W. 登録日 2018-06-11 公開日 2018-11-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Oligopeptide-binding protein from nontypeableHaemophilus influenzaehas ligand-specific sites to accommodate peptides and heme in the binding pocket. J. Biol. Chem., 294, 2019
5LCJ	In-Gel Activity-Based Protein Profiling of a Clickable Covalent Erk 1/2 Inhibitor 分子名称: Mitogen-activated protein kinase 1, SULFATE ION, [(1~{R},4~{Z})-cyclooct-4-en-1-yl] ~{N}-[4-[4-[[5-chloranyl-4-[[2-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate 著者 O'Reilly, M, Wright, D. 登録日 2016-06-22 公開日 2016-07-20 最終更新日 2016-08-31 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 In-gel activity-based protein profiling of a clickable covalent ERK1/2 inhibitor. Mol Biosyst, 12, 2016
6DSY	Bst DNA polymerase I post-chemistry (n+1) structure 分子名称: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... 著者 Chim, N, Jackson, L.N, Chaput, J.C. 登録日 2018-06-14 公開日 2018-10-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
6DWO	Crystal structure of alpha-1-2-mannosidase from Enterococcus faecalis V583 分子名称: ACETATE ION, Alpha-1,2-mannosidase, CALCIUM ION, ... 著者 Fisher, A.J, Li, Y. 登録日 2018-06-26 公開日 2019-10-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Enterococcus faecalis alpha 1-2-mannosidase (EfMan-I): an efficient catalyst for glycoprotein N-glycan modification. Febs Lett., 594, 2020
6DJR	Full-length human TRPC3 in GDN 分子名称: Transient Receptor Potential Cation Channel Subfamily C Member 3 著者 Sierra-Valdez, F.J, Azumaya, C.M, Nakagawa, T, Cordero-Morales, J.F. 登録日 2018-05-26 公開日 2018-08-29 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating. J. Biol. Chem., 293, 2018
5LCK	A Clickable Covalent ERK 1/2 Inhibitor 分子名称: Mitogen-activated protein kinase 1, SULFATE ION, ~{N}-[2-[[2-[(5-methoxypyridin-3-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]propanamide 著者 O'Reilly, M, Wright, D. 登録日 2016-06-22 公開日 2016-07-20 最終更新日 2018-03-28 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 In-gel activity-based protein profiling of a clickable covalent ERK1/2 inhibitor. Mol Biosyst, 12, 2016
6DL8	Crystal Structure of an influenza A hemagglutinin antibody Fab variant CH67:1203d4 chimera 分子名称: CH67:1203d4 FAB light chain, Ch67:1203d4 FAB heavy chain 著者 Dong, J, Finn, J.A, Crowe, J.E. 登録日 2018-05-31 公開日 2019-06-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.805 Å) 主引用文献 Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring. Structure, 28, 2020
6DM9	DHD15_extended 分子名称: DHD15_extended_A, DHD15_extended_B, SULFATE ION 著者 Bick, M.J, Chen, Z, Baker, D. 登録日 2018-06-04 公開日 2018-12-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Programmable design of orthogonal protein heterodimers. Nature, 565, 2019
6DQ7	LINKED KDM5A JMJ DOMAIN BOUND TO THE POTENTIAL HYDROLYSIS PRODUCT OF INHIBITOR N45 i.e. 3-((6-(4-(2-cyano-3-methylbut-2-enoyl)-1,4-diazepan-1-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoic acid 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Linked KDM5A Jmj Domain, ... 著者 Horton, J.R, Cheng, X. 登録日 2018-06-10 公開日 2019-06-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.852 Å) 主引用文献 Structure-based Engineering of Reversible Covalent Inhibitors Against Histone Lysine Demethylase 5A To Be Published
6DC1	Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-nitro-2-oxidanyl-benzenecarbonitrile, ... 著者 Jackson, C.J, Hong, N.-S, Carr, P.D. 登録日 2018-05-03 公開日 2018-08-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
6DVI	Wild-type Lactate Monooxygenase from Mycobacterium smegmatis 分子名称: FLAVIN MONONUCLEOTIDE, Lactate 2-monooxygenase, SULFATE ION 著者 Kean, K.M, Karplus, P.A. 登録日 2018-06-23 公開日 2018-10-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and role for active site lid of lactate monooxygenase from Mycobacterium smegmatis. Protein Sci., 28, 2019
5LF2	Crystal structure of laminin beta2 LE5-LF-LE6 分子名称: CALCIUM ION, CHLORIDE ION, Laminin subunit beta-2 著者 Pulido, D, Hohenester, E. 登録日 2016-06-30 公開日 2016-07-27 最終更新日 2017-03-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystallographic analysis of the laminin beta 2 short arm reveals how the LF domain is inserted into a regular array of LE domains. Matrix Biol., 57-58, 2017
6DGL	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Darglitazone 分子名称: (5Z)-5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl}methylidene)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma 著者 Shang, J, Kojetin, D.J. 登録日 2018-05-17 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Quantitative structural assessment of graded receptor agonism. Proc.Natl.Acad.Sci.USA, 116, 2019
6DHN	Bovine glutamate dehydrogenase complexed with Eu3+ 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLUTAMIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Smith, T.J. 登録日 2018-05-20 公開日 2018-07-25 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis. FEBS J., 278, 2011
6D9S	The (p)ppGpp-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) 分子名称: DI(HYDROXYETHYL)ETHER, GUANOSINE-5',3'-TETRAPHOSPHATE, Hypoxanthine phosphoribosyltransferase, ... 著者 Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. 登録日 2018-04-30 公開日 2019-05-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.105 Å) 主引用文献 Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. Elife, 8, 2019
6DNJ	Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 28 round 5 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1,2-benzoxazole, Kemp eliminase KE07 著者 Jackson, C.J, Hong, N.-S, Carr, P.D. 登録日 2018-06-06 公開日 2018-08-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
6DBO	Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs 分子名称: CALCIUM ION, Forward strand of substrate RSS DNA, Recombination activating gene 1 - MBP chimera, ... 著者 Wu, H, Liao, M, Ru, H, Mi, W. 登録日 2018-05-03 公開日 2018-08-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
5LP3	Three tetrameric rings of Isoaspartyl Dipeptidase fitted in an EM volume. 分子名称: Isoaspartyl dipeptidase 著者 Garcia-Seisdedos, H, Empereur-Mot, C, Elad, N, Levy, E.D. 登録日 2016-08-11 公開日 2017-07-26 最終更新日 2017-08-23 実験手法 ELECTRON MICROSCOPY (10.5 Å) 主引用文献 Proteins evolve on the edge of supramolecular self-assembly. Nature, 548, 2017
5LNG	Lectin domain of E. coli F9 pilus adhesin FmlH 分子名称: Putative Fml fimbrial adhesin FmlD, SULFATE ION 著者 Ruer, S, Conover, M.S, Kalas, V, Taganna, J, De Greve, H, Pinkner, J.S, Dodson, K.W, Hultgren, S.J, Remaut, H. 登録日 2016-08-04 公開日 2016-10-05 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection. Cell Host Microbe, 20, 2016
6DS6	Crystal structure of p300 ZZ domain in complex with histone H3 peptide 分子名称: CHLORIDE ION, Histone H3 peptide-Histone acetyltransferase p300 Chimeric protein, ZINC ION 著者 Zhang, Y, Kutateladze, T.G. 登録日 2018-06-13 公開日 2018-08-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3. Nat. Struct. Mol. Biol., 25, 2018
6DF8	Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS), pH 6.5 分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... 著者 Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. 登録日 2018-05-14 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.536 Å) 主引用文献 A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences. Biochemistry, 2020
6DSL	Consensus engineered intein (Cat) with atypical split site 分子名称: Consensus engineered intein CatC, Consensus engineered intein CatN 著者 Sekar, G, Stevens, A.J, Muir, T.W, Cowburn, D. 登録日 2018-06-14 公開日 2018-09-19 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 An Atypical Mechanism of Split Intein Molecular Recognition and Folding. J. Am. Chem. Soc., 140, 2018
6DGR	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with CAY10638 分子名称: (5Z)-5-({4-[2-(thiophen-2-yl)ethoxy]phenyl}methylidene)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma 著者 Shang, J, Kojetin, D.J. 登録日 2018-05-18 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Quantitative structural assessment of graded receptor agonism. Proc.Natl.Acad.Sci.USA, 116, 2019
6DUW	Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant 分子名称: Catenin alpha-2 著者 Ishiyama, N, Ikura, M. 登録日 2018-06-22 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions. Nat Commun, 9, 2018

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