6DS6

Crystal structure of p300 ZZ domain in complex with histone H3 peptide

Summary for 6DS6

• Entry DOI: 10.2210/pdb6ds6/pdb
• Descriptor: Histone H3 peptide-Histone acetyltransferase p300 Chimeric protein, ZINC ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: p300, zz domain, histone, chromatin, gene regulation, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 7012.01

Authors

Zhang, Y.,Kutateladze, T.G. (deposition date: 2018-06-13, release date: 2018-08-29, Last modification date: 2024-03-13)

• Primary citation: Zhang, Y.,Xue, Y.,Shi, J.,Ahn, J.,Mi, W.,Ali, M.,Wang, X.,Klein, B.J.,Wen, H.,Li, W.,Shi, X.,Kutateladze, T.G.; The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3.; Nat. Struct. Mol. Biol., 25:841-849, 2018; PubMed: 30150647; DOI: 10.1038/s41594-018-0114-9

Experimental method

X-RAY DIFFRACTION (1.95 Å)