PDB: 3581 件ウェブページステータス検索Chemie searchBIRD

---

8SGO	Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus pregnenolone sulfate 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ... 著者 Legesse, D.H, Fan, C, Teng, J, Zhuang, Y, Howard, R.J, Noviello, C.M, Lindahl, E, Hibbs, R.E. 登録日 2023-04-12 公開日 2023-08-30 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Structural insights into opposing actions of neurosteroids on GABA A receptors. Nat Commun, 14, 2023
4EWS	Crystal structure of cholesteryl ester transfer protein in complex with inhibitors 分子名称: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CETP, CHLORIDE ION, ... 著者 Liu, S, Qiu, X. 登録日 2012-04-27 公開日 2012-09-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Crystal structures of cholesteryl ester transfer protein in complex with inhibitors. J.Biol.Chem., 287, 2012
7P18	Crystal structure of 3-ketosteroid delta1-dehydrogenase from Sterolibacterium denitrificans in complex with 1,4-androstadiene-3,17-dione 分子名称: 3-oxosteroid 1-dehydrogenase, ANDROSTA-1,4-DIENE-3,17-DIONE, DI(HYDROXYETHYL)ETHER, ... 著者 Wojcik, P, Mrugala, B, Kurpiewska, K, Szaleniec, M. 登録日 2021-07-01 公開日 2021-07-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure, Mutagenesis, and QM:MM Modeling of 3-Ketosteroid Delta 1 -Dehydrogenase from Sterolibacterium denitrificans ─The Role of a New Putative Membrane-Associated Domain and Proton-Relay System in Catalysis. Biochemistry, 62, 2023
7ONB	Structure of the U2 5' module of the A3'-SSA complex 分子名称: MINX, PHD finger-like domain-containing protein 5A, RNU2, ... 著者 Cretu, C, Pena, V. 登録日 2021-05-25 公開日 2021-08-04 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
3LL5	Crystal structure of T. acidophilum isopentenyl phosphate kinase product complex 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Mabanglo, M.F, Hill, C.P. 登録日 2010-01-28 公開日 2010-06-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.987 Å) 主引用文献 X-ray structures of isopentenyl phosphate kinase. Acs Chem.Biol., 5, 2010
7OO6	Mechanosensitive channel MscS solubilized with DDM in closed conformation with added lipid 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, DODECYL-BETA-D-MALTOSIDE, Mechanosensitive channel of small conductance (MscS) 著者 Rasmussen, T, Flegler, V.J, Boettcher, B. 登録日 2021-05-26 公開日 2021-09-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Mechanosensitive channel gating by delipidation. Proc.Natl.Acad.Sci.USA, 118, 2021
3LKK	Crystal structure of the isopentenyl phosphate kinase substrate complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Gamma-glutamyl kinase related protein, Isopentenyl phosphate 著者 Mabanglo, M.F, Hill, C.P. 登録日 2010-01-27 公開日 2010-06-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 X-ray structures of isopentenyl phosphate kinase. Acs Chem.Biol., 5, 2010
6U8A	CBD-bound full-length rat TRPV2 in nanodiscs, state 1 分子名称: Transient receptor potential cation channel subfamily V member 2, cannabidiol 著者 Pumroy, R.A, Moiseenkova-Bell, V.Y. 登録日 2019-09-04 公開日 2019-10-16 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular mechanism of TRPV2 channel modulation by cannabidiol. Elife, 8, 2019
6U88	CBD-bound full-length rat TRPV2 in nanodiscs, state 2 分子名称: Transient receptor potential cation channel subfamily V member 2, cannabidiol 著者 Pumroy, R.A, Moiseenkova-Bell, V.Y. 登録日 2019-09-04 公開日 2019-10-16 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Molecular mechanism of TRPV2 channel modulation by cannabidiol. Elife, 8, 2019
5TL6	Crystal structure of SARS-CoV papain-like protease in complex with the C-terminal domain of human ISG15 分子名称: Replicase polyprotein 1ab, SULFATE ION, Ubiquitin-like protein ISG15, ... 著者 Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. 登録日 2016-10-10 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.618 Å) 主引用文献 Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species. J. Mol. Biol., 429, 2017
6UP0	Structure of the Mango-III fluorescent aptamer bound to YO3-Biotin 分子名称: MAGNESIUM ION, Mango-III fluorescent aptamer, POTASSIUM ION, ... 著者 Trachman, R.J, Ferre-D'Amare, A.R. 登録日 2019-10-16 公開日 2020-10-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Fluorogenic aptamers resolve the flexibility of RNA junctions using orientation-dependent FRET. Rna, 27, 2021
5SYE	Near-atomic resolution cryo-EM reconstruction of doubly bound Taxol- and peloruside-stabilized microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Kellogg, E.H, Nogales, E. 登録日 2016-08-10 公開日 2017-02-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures. J. Mol. Biol., 429, 2017
6V4F	Crystal Structure Analysis of Zebra Fish MDMX 分子名称: Protein Mdm4, SULFATE ION, Stapled Peptide LSQETF(0EH)DLWKLE(MK8)EN(NH2) 著者 Seo, H.-S, Dhe-Paganon, S. 登録日 2019-11-27 公開日 2020-04-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Identification of a Structural Determinant for Selective Targeting of HDMX. Structure, 28, 2020
5SYC	Near-atomic resolution cryo-EM reconstruction of peloruside-stabilized microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Kellogg, E.H, Nogales, E. 登録日 2016-08-10 公開日 2017-02-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures. J. Mol. Biol., 429, 2017
7QHB	Active state of GluA1/2 in complex with TARP gamma 8, L-glutamate and CTZ 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, CYCLOTHIAZIDE, ... 著者 Herguedas, B, Kohegyi, B, Zhang, D, Greger, I.H. 登録日 2021-12-11 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor. Nat Commun, 13, 2022
6W4F	NMR-driven structure of KRAS4B-GDP homodimer on a lipid bilayer nanodisc 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... 著者 Lee, K, Fang, Z, Enomoto, M, Gasmi-Seabrook, G.M, Zheng, L, Marshall, C.B, Ikura, M. 登録日 2020-03-10 公開日 2020-04-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement. Angew.Chem.Int.Ed.Engl., 59, 2020
5TL7	Crystal structure of SARS-CoV papain-like protease in complex with C-terminal domain mouse ISG15 分子名称: Replicase polyprotein 1ab, Ubiquitin-like protein ISG15, ZINC ION 著者 Daczkowski, C.D, Dzimianski, J.V, Pegan, S.D. 登録日 2016-10-10 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species. J. Mol. Biol., 429, 2017
6W4E	NMR-driven structure of KRAS4B-GTP homodimer on a lipid bilayer nanodisc 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Apolipoprotein A-I, ... 著者 Lee, K, Fang, Z, Enomoto, M, Gasmi-Seabrook, G.M, Zheng, L, Marshall, C.B, Ikura, M. 登録日 2020-03-10 公開日 2020-04-15 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement. Angew.Chem.Int.Ed.Engl., 59, 2020
6VYK	Cryo-EM structure of mechanosensitive channel MscS in PC-18:1 nanodiscs 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mechanosensitive channel MscS 著者 Zhang, Y, Daday, C, Gu, R, Cox, C.D, Martinac, B, Groot, B, Walz, T. 登録日 2020-02-27 公開日 2021-02-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Visualization of the mechanosensitive ion channel MscS under membrane tension. Nature, 590, 2021
6W30	Protein Tyrosine Phosphatase 1B Bound to Amorphadiene 分子名称: Amorphadiene, GLYCEROL, MAGNESIUM ION, ... 著者 Sarkar, A, Kim, E.Y, Hongdusit, A, Sankaran, B, Fox, J. 登録日 2020-03-08 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products. Acs Synth Biol, 10, 2021
6V4H	Crystal Structure Analysis of Zebra Fish MDMX 分子名称: Protein Mdm4, Stapled Peptide LSQETF(0EH)DLWKLL(MK8)EN(NH2) 著者 Seo, H.-S, Dhe-Paganon, S. 登録日 2019-11-27 公開日 2020-04-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Identification of a Structural Determinant for Selective Targeting of HDMX. Structure, 28, 2020
3OGL	Structure of COI1-ASK1 in complex with JA-isoleucine and the JAZ1 degron 分子名称: Coronatine-insensitive protein 1, JAZ1 incomplete degron peptide, N-({(1R,2S)-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl}acetyl)-L-isoleucine, ... 著者 Sheard, L.B, Tan, X, Mao, H, Withers, J, Ben-Nissan, G, Hinds, T.R, Hsu, F, Sharon, M, Browse, J, He, S.Y, Rizo, J, Howe, G.A, Zheng, N. 登録日 2010-08-17 公開日 2010-10-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor. Nature, 468, 2010
5UPH	Lipids bound lysosomal integral membrane protein 2 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-beta-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Conrad, K.S, Liu, S. 登録日 2017-02-03 公開日 2017-12-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies. Nat Commun, 8, 2017
5KMG	Near-atomic cryo-EM structure of PRC1 bound to the microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Kellogg, E.H, Howes, S, Ti, S.-C, Ramirez-Aportela, E, Kapoor, T.M, Chacon, P, Nogales, E. 登録日 2016-06-27 公開日 2016-08-03 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Near-atomic cryo-EM structure of PRC1 bound to the microtubule. Proc.Natl.Acad.Sci.USA, 113, 2016
6AAO	Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TCO*Lys 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Yanagisawa, T, Kuratani, M, Yokoyama, S. 登録日 2018-07-18 公開日 2019-04-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.403 Å) 主引用文献 Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Cell Chem Biol, 26, 2019

<57585960616263646566676869707172>