5TL6

Crystal structure of SARS-CoV papain-like protease in complex with the C-terminal domain of human ISG15

Summary for 5TL6

Entry DOI	10.2210/pdb5tl6/pdb
Related	5TL7 5TLA
Descriptor	Replicase polyprotein 1ab, Ubiquitin-like protein ISG15, ZINC ION, ... (5 entities in total)
Functional Keywords	signaling protein, hydrolase, signaling protein-hydrolase complex, signaling protein/hydrolase
Biological source	Human SARS coronavirus (SARS-CoV) More
Total number of polymer chains	4
Total formula weight	89664.65
Authors	Dzimianski, J.V.,Daczkowski, C.M.,Pegan, S.D. (deposition date: 2016-10-10, release date: 2017-05-03, Last modification date: 2023-10-04)
Primary citation	Daczkowski, C.M.,Dzimianski, J.V.,Clasman, J.R.,Goodwin, O.,Mesecar, A.D.,Pegan, S.D. Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species. J. Mol. Biol., 429:1661-1683, 2017 Cited by PubMed: 28438633 DOI: 10.1016/j.jmb.2017.04.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.618 Å)

Structure validation