6W30

Protein Tyrosine Phosphatase 1B Bound to Amorphadiene

Summary for 6W30

Entry DOI	10.2210/pdb6w30/pdb
Descriptor	Tyrosine-protein phosphatase non-receptor type 1, GLYCEROL, Amorphadiene, ... (5 entities in total)
Functional Keywords	ptp1b, allosteric inhibitor, terpenoid, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	38757.53
Authors	Sarkar, A.,Kim, E.Y.,Hongdusit, A.,Sankaran, B.,Fox, J. (deposition date: 2020-03-08, release date: 2021-05-26, Last modification date: 2023-10-18)
Primary citation	Sarkar, A.,Kim, E.Y.,Jang, T.,Hongdusit, A.,Kim, H.,Choi, J.M.,Fox, J.M. Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products. Acs Synth Biol, 10:1505-1519, 2021 Cited by PubMed: 33988973 DOI: 10.1021/acssynbio.1c00074 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation