PDB: 19952 件ウェブページステータス検索Chemie searchBIRD

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3UAJ	Crystal structure of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, monoclonal antibody 5H2, ... 著者 Cockburn, J.J.B, Stura, E.A, Navarro-Sanchez, M.E, Rey, F.A. 登録日 2011-10-21 公開日 2011-12-14 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.232 Å) 主引用文献 Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus. Embo J., 31, 2012
3TRV	Crystal structure of quasiracemic villin headpiece subdomain containing (F5Phe17) substitution 分子名称: D-Villin-1, ISOPROPYL ALCOHOL, L-Villin-1, ... 著者 Mortenson, D.E, Satyshur, K.A, Gellman, S.H, Forest, K.T. 登録日 2011-09-11 公開日 2012-01-25 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations. J.Am.Chem.Soc., 134, 2012
3TRY	Crystal structure of racemic villin headpiece subdomain in space group I-4c2 分子名称: D-Villin-1, SULFATE ION 著者 Mortenson, D.E, Satyshur, K.A, Gellman, S.H, Forest, K.T. 登録日 2011-09-11 公開日 2012-01-25 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations. J.Am.Chem.Soc., 134, 2012
3TTD	Crystal structure of E. coli HypF with AMP-CPP and carbamoyl phosphate 分子名称: MAGNESIUM ION, Transcriptional regulatory protein, ZINC ION 著者 Petkun, S, Shi, R, Li, Y, Cygler, M. 登録日 2011-09-14 公開日 2011-12-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of Hydrogenase Maturation Protein HypF with Reaction Intermediates Shows Two Active Sites. Structure, 19, 2011
3TLV	The GLIC pentameric Ligand-Gated Ion Channel Loop2-22' oxidized mutant in a locally-closed conformation (LC3 subtype) 分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-08-30 公開日 2012-05-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3TNI	structure of CDK9/cyclin T F241L 分子名称: Cyclin-T1, Cyclin-dependent kinase 9 著者 Baumli, S, Hole, A.J, Endicott, J.A. 登録日 2011-09-01 公開日 2012-02-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.234 Å) 主引用文献 The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN508. Acs Chem.Biol., 7, 2012
3TVZ	Structure of Bacillus subtilis HmoB 分子名称: Putative uncharacterized protein yhgC 著者 Choe, J, Choi, S, Park, S. 登録日 2011-09-21 公開日 2012-07-11 最終更新日 2019-10-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Bacillus subtilis HmoB is a heme oxygenase with a novel structure. Bmb Rep, 45, 2012
3TPW	CRYSTAL STRUCTURE OF M-PMV DUTPASE - DUPNPP complex revealing distorted ligand geometry (approach intermediate) 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDO HYDROLASE, ... 著者 Barabas, O, Nemeth, V, Vertessy, B.G. 登録日 2011-09-08 公開日 2011-10-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Snapshots of Enzyme-Catalysed Phosphate Ester Hydrolysis Directly Visualize In-line Attack and Inversion to be published
3SA3	Crystal structure of wild-type HIV-1 protease in complex with AG23 分子名称: ACETATE ION, N~2~-acetyl-N-[(2S,3R)-4-{(1,3-benzothiazol-6-ylsulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-L-isoleucinamide, PHOSPHATE ION, ... 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
3SAB	Crystal structure of wild-type HIV-1 protease in complex with AF78 分子名称: 3-hydroxy-N-[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](3-phenylpropyl)amino}-1-phenylbutan-2-yl]benzamide, PHOSPHATE ION, Protease 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
3SD2	Crystal structure of a putative member of duf3244 protein family (BT_3571) from Bacteroides thetaiotaomicron vpi-5482 at 1.40 A resolution 分子名称: Putative member of DUF3244 protein family 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-06-08 公開日 2011-06-29 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of a Putative member of DUF3244 protein family (BT_3571) from Bacteroides thetaiotaomicron VPI-5482 at 1.40 A resolution To be published
3SEK	Crystal Structure of the Myostatin:Follistatin-like 3 Complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Follistatin-related protein 3, Growth/differentiation factor 8 著者 Cash, J.N, Thompson, T.B. 登録日 2011-06-10 公開日 2011-11-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Structure of myostatinfollistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding. J.Biol.Chem., 287, 2012
3SDI	Structure of yeast 20S open-gate proteasome with Compound 20 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N~4~-(2,2-dimethylpropyl)-N~1~-{(2S)-1-[(4-methylbenzyl)amino]-1-oxo-4-phenylbutan-2-yl}-N~2~-[(5-methyl-1,2-oxazol-3-yl)carbonyl]-L-aspartamide, ... 著者 Sintchak, M.D. 登録日 2011-06-09 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg.Med.Chem.Lett., 20, 2010
3SFG	crystal structure of murine norovirus RNA dependent RNA polymerase in complex with 2thiouridine(2TU) 分子名称: 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, GLYCEROL, MAGNESIUM ION, ... 著者 Kim, K.H, Alam, I. 登録日 2011-06-13 公開日 2012-05-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.209 Å) 主引用文献 Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin. Virology, 426, 2012
3S9T	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-chloro-5-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-02 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SA2	Bacuills anthracis Dihydrofolate Reductase bound propargyl-linked TMP analog, UCP1014 分子名称: 6-ethyl-5-[3-(5-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Anderson, A.C, Beierlein, J.M. 登録日 2011-06-02 公開日 2012-06-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 SAR studies of heterocyclic propargyl-linked TMP analogs to Bacillus dihydrofolate reductase to be published
3SAA	Crystal structure of Wild-type HIV-1 protease in complex With AF77 分子名称: N-[(2S,3R)-4-{(cyclohexylmethyl)[(4-methoxyphenyl)sulfonyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-3-hydroxybenzamide, PHOSPHATE ION, Protease 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
3SB6	Cu-mediated Dimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization 分子名称: CHLORIDE ION, COPPER (II) ION, Lysozyme 著者 Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. 登録日 2011-06-03 公開日 2011-09-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
3SHP	Crystal structure of putative acetyltransferase from Sphaerobacter thermophilus DSM 20745 分子名称: Putative acetyltransferase Sthe_0691, S,R MESO-TARTARIC ACID 著者 Chang, C, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2011-06-16 公開日 2011-07-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structure of putative acetyltransferase from Sphaerobacter thermophilus DSM 20745 To be Published
3SI2	Structure of glycosylated murine glutaminyl cyclase in presence of the inhibitor PQ50 (PDBD150) 分子名称: 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Parthier, C, Carrillo, D, Stubbs, M.T. 登録日 2011-06-17 公開日 2011-06-29 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of Glycosylated Mammalian Glutaminyl Cyclases Reveal Conformational Variability near the Active Center. Biochemistry, 50, 2011
3SIE	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors 分子名称: 5-bromo-6-ethyl-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one, cGMP-specific 3',5'-cyclic phosphodiesterase 著者 Chen, T.T, Chen, T, Xu, Y.C. 登録日 2011-06-17 公開日 2011-08-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. J.Med.Chem., 54, 2011
3SK9	Crystal structure of the Thermus thermophilus cas3 HD domain 分子名称: Putative uncharacterized protein TTHB187 著者 Bailey, S, Mulepati, S. 登録日 2011-06-22 公開日 2011-07-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3). J.Biol.Chem., 286, 2011
3SGW	Crystal structure of ribose-5-phosphate isomerase B RpiB from Coccidioides immitis semi-covalently bound to malonic acid 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MALONIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-06-15 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. Bmc Struct.Biol., 11, 2011
3SHL	Crystal structure of Staphylococcal nuclease variant Delta+PHS V74KL25A at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Caro, J.A, Sue, G, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2011-06-16 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Redirection of internal ionizable residues by engineered cavities To be Published
3SL5	Crystal structure of the catalytic domain of PDE4D2 complexed with compound 10d 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... 著者 Feil, S.F. 登録日 2011-06-24 公開日 2011-10-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011

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