3TNI

structure of CDK9/cyclin T F241L

Summary for 3TNI

Entry DOI	10.2210/pdb3tni/pdb
Related	3TNH 3TNW
Descriptor	Cyclin-dependent kinase 9, Cyclin-T1 (2 entities in total)
Functional Keywords	cyclin dependent kinase, kinase, cyclin, phosphotransfer, cdk-cyclin complex, phosphorylated on threonine 186, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P50750 O60563
Total number of polymer chains	2
Total formula weight	68193.54
Authors	Baumli, S.,Hole, A.J.,Endicott, J.A. (deposition date: 2011-09-01, release date: 2012-02-15, Last modification date: 2012-05-30)
Primary citation	Baumli, S.,Hole, A.J.,Noble, M.E.,Endicott, J.A. The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN508. Acs Chem.Biol., 7:811-816, 2012 Cited by PubMed: 22292676 DOI: 10.1021/cb2004516 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.234 Å)

Structure validation