PDB: 97310 件ウェブページステータス検索Chemie searchBIRD

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8GAF	Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications 分子名称: Cas11, Cas5, Cas7, ... 著者 Hu, C, Nam, K.H, Ke, A. 登録日 2023-02-22 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
8GAM	Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications 分子名称: Cas11, Cas5, Cas7, ... 著者 Hu, C, Nam, K.H, Ke, A. 登録日 2023-02-23 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
3UNI	Crystal Structure of Bovine Milk Xanthine Dehydrogenase with NADH Bound 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-HYDROXYBENZOIC ACID, CALCIUM ION, ... 著者 Eger, B.T, Okamoto, K, Nishino, T, Pai, E.F. 登録日 2011-11-15 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Protein conformational gating of enzymatic activity in xanthine oxidoreductase. J.Am.Chem.Soc., 134, 2012
1HDI	Pig muscle 3-PHOSPHOGLYCERATE KINASE complexed with 3-PG and MgADP. 分子名称: 3-PHOSPHOGLYCERIC ACID, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... 著者 Szilagyi, A.N, Ghosh, M, Garman, E, Vas, M. 登録日 2000-11-16 公開日 2001-02-26 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A 1.8 A resolution structure of pig muscle 3-phosphoglycerate kinase with bound MgADP and 3-phosphoglycerate in open conformation: new insight into the role of the nucleotide in domain closure. J. Mol. Biol., 306, 2001
8Y0W	dormant ribosome with eIF5A, eEF2 and SERBP1 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Du, M, Zeng, F. 登録日 2024-01-23 公開日 2024-02-07 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 dormant ribosome with eIF5A, eEF2 and SERBP1 To Be Published
1GOX	REFINED STRUCTURE OF SPINACH GLYCOLATE OXIDASE AT 2 ANGSTROMS RESOLUTION 分子名称: (S)-2-HYDROXY-ACID OXIDASE, PEROXISOMAL, FLAVIN MONONUCLEOTIDE 著者 Lindqvist, Y. 登録日 1989-06-14 公開日 1989-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Refined structure of spinach glycolate oxidase at 2 A resolution. J.Mol.Biol., 209, 1989
3UNA	Crystal Structure of Bovine Milk Xanthine Dehydrogenase with NAD Bound 分子名称: 2-HYDROXYBENZOIC ACID, CALCIUM ION, CARBONATE ION, ... 著者 Eger, B.T, Okamoto, K, Nishino, T, Pai, E.F. 登録日 2011-11-15 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Protein conformational gating of enzymatic activity in xanthine oxidoreductase. J.Am.Chem.Soc., 134, 2012
1PZE	T.gondii LDH1 apo form 分子名称: lactate dehydrogenase 著者 Kavanagh, K.L, Elling, R.A, Wilson, D.K. 登録日 2003-07-10 公開日 2004-02-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use. Biochemistry, 43, 2004
1PZG	T.gondii LDH1 complexed with APAD and sulfate at 1.6 Angstroms 分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, SULFATE ION, lactate dehydrogenase 著者 Kavanagh, K.L, Elling, R.A, Wilson, D.K. 登録日 2003-07-10 公開日 2004-02-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use. Biochemistry, 43, 2004
1GPM	ESCHERICHIA COLI GMP SYNTHETASE COMPLEXED WITH AMP AND PYROPHOSPHATE 分子名称: ADENOSINE MONOPHOSPHATE, CITRIC ACID, GMP SYNTHETASE, ... 著者 Tesmer, J.J.G. 登録日 1995-04-04 公開日 1996-01-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families. Nat.Struct.Biol., 3, 1996
3VKG	X-ray structure of an MTBD truncation mutant of dynein motor domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dynein heavy chain, cytoplasmic, ... 著者 Kon, T, Oyama, T, Shimo-Kon, R, Suto, K, Kurisu, G. 登録日 2011-11-16 公開日 2012-03-14 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The 2.8 A crystal structure of the dynein motor domain Nature, 484, 2012
1BOF	GI-ALPHA-1 BOUND TO GDP AND MAGNESIUM 分子名称: GI ALPHA 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Coleman, D.E, Sprang, S.R. 登録日 1998-08-04 公開日 1999-01-06 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of the G protein Gi alpha 1 complexed with GDP and Mg2+: a crystallographic titration experiment. Biochemistry, 37, 1998
1THY	REFINED STRUCTURES OF SUBSTRATE-BOUND AND PHOSPHATE-BOUND THYMIDYLATE SYNTHASE FROM LACTOBACILLUS CASEI 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE 著者 Finer-Moore, J, Stroud, R. 登録日 1993-04-02 公開日 1993-10-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei. J.Mol.Biol., 232, 1993
5BXV	eIF4E complex 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1 著者 Sekiyama, N, Arthanari, H, Papdopoulos, E, Rodriguez-Mias, R.A, Wagner, G, Leger-Abraham, M. 登録日 2015-06-09 公開日 2015-07-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1. Proc.Natl.Acad.Sci.USA, 112, 2015
1TMU	Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Hirudin variant-2, ... 著者 Priestle, J.P, Gruetter, M.G. 登録日 1994-05-26 公開日 1994-09-30 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms. Protein Sci., 2, 1993
1ZL1	Crystal structure of the complex of signalling protein from sheep (SPS-40) with a designed peptide Trp-His-Trp reveals significance of Asn79 and Trp191 in the complex formation 分子名称: Chitinase-3 like protein 1, TRP-HIS-TRP peptide, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Ethayathulla, A.S, Srivastava, D.B, Singh, N, Kumar, J, Somvanshi, R.K, Sharma, S, Dey, S, Singh, T.P. 登録日 2005-05-05 公開日 2005-05-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of the complex of signalling protein from sheep (SPS-40) with a designed peptide Trp-His-Trp reveals significance of Asn79 and Trp191 in the complex formation TO BE PUBLISHED
4BES	Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein in complex with cytidine monophosphate and phosphocholine 分子名称: CYTIDINE-5'-MONOPHOSPHATE, PHOSPHOCHOLINE, PHOSPHOCHOLINE TRANSFERASE ANKX, ... 著者 Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J. 登録日 2013-03-12 公開日 2013-04-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain. Embo J., 32, 2013
8OMU	Cryo-EM structure of rat SLC22A6 bound to alpha-ketoglutaric acid in a low occupancy state 分子名称: Solute carrier family 22 member 6, Synthetic nanobody (Sybody) 著者 Parker, J.L, Kato, T, Newstead, S. 登録日 2023-03-31 公開日 2023-07-19 最終更新日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1. Nat.Struct.Mol.Biol., 30, 2023
1MLC	MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH LYSOZYME 分子名称: HEN EGG WHITE LYSOZYME, IGG1-KAPPA D44.1 FAB (HEAVY CHAIN), IGG1-KAPPA D44.1 FAB (LIGHT CHAIN) 著者 Braden, B.C, Souchon, H, Eisele, J.-L, Bentley, G.A, Bhat, T.N, Navaza, J, Poljak, R.J. 登録日 1995-03-10 公開日 1995-06-03 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1. J.Mol.Biol., 243, 1994
7MDC	Full-length wildtype ClbP inhibited by hexanoyl-D-asparagine boronic acid 分子名称: (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Beta-lactamase, CHLORIDE ION, ... 著者 Velilla, J.A, Volpe, M.R, Gaudet, R. 登録日 2021-04-03 公開日 2022-09-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A small molecule inhibitor prevents gut bacterial genotoxin production. Nat.Chem.Biol., 19, 2023
8TO0	48-nm repeating structure of doublets from mouse sperm flagella 分子名称: Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... 著者 Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A. 登録日 2023-08-02 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 ELECTRON MICROSCOPY (7.7 Å) 主引用文献 De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell, 186, 2023
1LYW	CATHEPSIN D AT PH 7.5 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CATHEPSIN D 著者 Lee, A.Y, Gulnik, S.V, Erickson, J.W. 登録日 1998-06-30 公開日 1999-07-22 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Conformational switching in an aspartic proteinase. Nat.Struct.Biol., 5, 1998
8B37	Crystal structure of Pyrobaculum aerophilum potassium-independent proton pumping membrane integral pyrophosphatase in complex with imidodiphosphate and magnesium, and with bound sulphate 分子名称: IMIDODIPHOSPHORIC ACID, K(+)-insensitive pyrophosphate-energized proton pump, MAGNESIUM ION, ... 著者 Strauss, J, Wilkinson, C, Vidilaseris, K, Ribeiro, O, Liu, J, Hillier, J, Malinen, A, Gehl, B, Jeuken, L.C, Pearson, A.R, Goldman, A. 登録日 2022-09-16 公開日 2024-01-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.84 Å) 主引用文献 Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases. Embo Rep., 25, 2024
8BW9	Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP 分子名称: Connector enhancer of KSR protein CNK, Dual specificity mitogen-activated protein kinase kinase dSOR1, KSR, ... 著者 Maisonneuve, P, Fronzes, R, Sicheri, F. 登録日 2022-12-06 公開日 2024-02-21 最終更新日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nat.Struct.Mol.Biol., 31, 2024
1IM6	CRYSTAL STRUCTURE OF UNLIGATED HPPK(R82A) FROM E.COLI AT 1.74 ANGSTROM RESOLUTION 分子名称: 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION 著者 Blaszczyk, J, Ji, X. 登録日 2001-05-09 公開日 2003-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies Biochemistry, 42, 2003

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