8B37

Crystal structure of Pyrobaculum aerophilum potassium-independent proton pumping membrane integral pyrophosphatase in complex with imidodiphosphate and magnesium, and with bound sulphate

Summary for 8B37

• Entry DOI: 10.2210/pdb8b37/pdb
• Descriptor: K(+)-insensitive pyrophosphate-energized proton pump, MAGNESIUM ION, IMIDODIPHOSPHORIC ACID, ... (5 entities in total)
• Functional Keywords: k+-independence, ion-selectivity, membrane proteins, membrane-bound pyrophosphatases., membrane protein
• Biological source: Pyrobaculum aerophilum
• Total number of polymer chains: 2
• Total formula weight: 153466.38

Authors

Strauss, J.,Wilkinson, C.,Vidilaseris, K.,Ribeiro, O.,Liu, J.,Hillier, J.,Malinen, A.,Gehl, B.,Jeuken, L.C.,Pearson, A.R.,Goldman, A. (deposition date: 2022-09-16, release date: 2024-01-17, Last modification date: 2024-02-21)

• Primary citation: Strauss, J.,Wilkinson, C.,Vidilaseris, K.,de Castro Ribeiro, O.M.,Liu, J.,Hillier, J.,Wichert, M.,Malinen, A.M.,Gehl, B.,Jeuken, L.J.,Pearson, A.R.,Goldman, A.; Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases.; Embo Rep., 25:853-875, 2024; PubMed: 38182815; DOI: 10.1038/s44319-023-00037-x

Experimental method

X-RAY DIFFRACTION (3.84 Å)