PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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5CGY	Fab fragment of Chikungunya virus neutralizing human monoclonal antibody 4J21 分子名称: Heavy Chain of Fab, Light Chain of Fab 著者 Long, F, Crowe, J.E, Rossmann, M.G. 登録日 2015-07-09 公開日 2015-11-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity. Proc.Natl.Acad.Sci.USA, 112, 2015
6DD6	Crystal structure of bacterial (6-4) photolyase PhrB from in situ serial Laue diffraction 分子名称: 1-deoxy-1-(6,7-dimethyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ... 著者 Ren, Z. 登録日 2018-05-09 公開日 2018-07-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal-on-crystal chips for in situ serial diffraction at room temperature. Lab Chip, 18, 2018
5CHW	Structure of ISG15 in space group P212121 分子名称: GLYCEROL, SULFATE ION, Ubiquitin-like protein ISG15 著者 Fritz, G, Basters, A. 登録日 2015-07-10 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of ISG15 in space group P212121 To Be Published
5BWZ	Crystal structure of S39E HDAC8 in complex with Droxinostat 分子名称: Droxinostat, GLYCEROL, Histone deacetylase 8, ... 著者 Decroos, C, Christianson, D.W. 登録日 2015-06-08 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant. Biochemistry, 58, 2019
2OLQ	How Does an Enzyme Recognize CO2? 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CARBON DIOXIDE, MAGNESIUM ION, ... 著者 Puttick, J, Goldie, H, Cotelesage, J.J, Rajabi, B, Novakovski, B, Delbaere, L.T. 登録日 2007-01-19 公開日 2007-06-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 How does an enzyme recognize CO2? Int.J.Biochem.Cell Biol., 39, 2007
2PR6	Structural Basis for Light-dependent Signaling in the Dimeric LOV Photosensor YtvA (Light Structure) 分子名称: Blue-light photoreceptor, FLAVIN MONONUCLEOTIDE 著者 Moglich, A, Moffat, K. 登録日 2007-05-03 公開日 2007-08-07 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Basis for Light-dependent Signaling in the Dimeric LOV Domain of the Photosensor YtvA. J.Mol.Biol., 373, 2007
2FAI	Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-2M and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide 分子名称: 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2 著者 Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. 登録日 2005-12-07 公開日 2006-05-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem., 281, 2006
2PRT	Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA 分子名称: DNA (5'-D(*CP*AP*GP*AP*CP*GP*CP*CP*CP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*GP*GP*GP*CP*GP*TP*CP*TP*G)-3'), Wilms tumor 1, ... 著者 Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E. 登録日 2007-05-04 公開日 2008-03-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA J.Mol.Biol., 372, 2007
2F6X	Crystal Structure of (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase complexed with sn-G1P and MPD 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase, SN-GLYCEROL-1-PHOSPHATE 著者 Payandeh, J.M. 登録日 2005-11-29 公開日 2006-01-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme J.Biol.Chem., 281, 2006
2FDU	Microsomal P450 2A6 with the inhibitor N,N-Dimethyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound 分子名称: Cytochrome P450 2A6, N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Yano, J.K, Stout, C.D, Johnson, E.F. 登録日 2005-12-14 公開日 2006-11-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization. J.Med.Chem., 49, 2006
2PFF	Structural Insights of Yeast Fatty Acid Synthase 分子名称: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Tail protein 著者 Xiong, Y, Lomakin, I.B, Steitz, T.A. 登録日 2007-04-04 公開日 2007-07-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural Insights of Yeast Fatty Acid Synthase Cell(Cambridge,Mass.), 129, 2007
2PI4	T7RNAP complexed with a phi10 protein and initiating GTPs. 分子名称: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*CP*CP*TP*AP*TP*AP*GP*TP*GP*AP*GP*TP*CP*GP*TP*AP*TP*TP*A)-3', 5'-D(*TP*AP*AP*TP*AP*CP*GP*AP*CP*TP*CP*AP*CP*T)-3', ... 著者 Kennedy, W.P, Momand, J.R, Yin, Y.W. 登録日 2007-04-12 公開日 2007-06-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanism for de novo RNA synthesis and initiating nucleotide specificity by t7 RNA polymerase. J.Mol.Biol., 370, 2007
2FK2	Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, Cu(I)-bound 分子名称: Amyloid beta A4 protein precursor, COPPER (I) ION 著者 Kong, G.K.-W, Parker, M.W. 登録日 2006-01-03 公開日 2007-01-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Studies of the Alzheimer's Amyloid Precursor Protein Copper-binding Domain Reveal How it Binds Copper Ions J.Mol.Biol., 367, 2007
2EYS	A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition 分子名称: ACETIC ACID, NKT15 著者 Kjer-Nielsen, L, Borg, N.A. 登録日 2005-11-09 公開日 2006-03-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition J.Exp.Med., 203, 2006
5E9Z	Cytochrome P450 BM3 mutant M11 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Bifunctional cytochrome P450/NADPH--P450 reductase, FE (II) ION, ... 著者 Capoferri, L, Leth, R, ter Haar, E, Mohanty, A.K, Grootenhuis, D.J, Vottero, E, Commandeur, J.N.M, Vermeulen, N.P.E, Jorgensen, F.S, Olsen, L, Geerke, D.P. 登録日 2015-10-15 公開日 2016-01-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations. Proteins, 84, 2016
5DKJ	Yeast 20S proteasome in complex with octreotide-PI 分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... 著者 Beck, P, Cui, H, Groll, M. 登録日 2015-09-03 公開日 2015-10-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation. Chemmedchem, 10, 2015
2PGB	Inhibitor-free human thrombin mutant C191A-C220A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Prothrombin, SULFATE ION 著者 Bush-Pelc, L.A, Marino, F, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E. 登録日 2007-04-09 公開日 2007-07-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery J.Biol.Chem., 282, 2007
2QBT	Structural Studies Reveal The Inactivation of E. coli L-aspartate aminotransferase by (S)-4,5-amino-dihydro-2-thiophenecarboxylic acid (SADTA) via Two Mechanisms (at pH 8.0) 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, Aspartate aminotransferase, ... 著者 Liu, D, Pozharski, E, Lepore, B, Fu, M, Silverman, R.B, Petsko, G.A, Ringe, D. 登録日 2007-06-18 公開日 2007-09-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Inactivation of Escherichia coli l-Aspartate Aminotransferase by (S)-4-Amino-4,5-dihydro-2-thiophenecarboxylic Acid Reveals "A Tale of Two Mechanisms". Biochemistry, 46, 2007
2FMA	Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, atomic resolution 分子名称: Amyloid beta A4 protein precursor, GLYCEROL 著者 Kong, G.K.-W. 登録日 2006-01-08 公開日 2007-01-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (0.85 Å) 主引用文献 Structure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolution. Acta Crystallogr.,Sect.F, 63, 2007
2R0Z	PFA1 FAB complexed with GripI peptide fragment 分子名称: GLYCEROL, GripI peptide fragment, IgG2a Fab fragment heavy chain, ... 著者 Gardberg, A.S, Dealwis, C. 登録日 2007-08-21 公開日 2007-10-16 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 Molecular basis for passive immunotherapy of Alzheimer's disease Proc.Natl.Acad.Sci.Usa, 104, 2007
2QF1	Rat cytosolic PEPCK in complex with oxaloacetic acid. 分子名称: MANGANESE (II) ION, OXALOACETATE ION, Phosphoenolpyruvate carboxykinase, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2007-06-26 公開日 2007-08-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid. Biochemistry, 46, 2007
2QAF	Crystal structure of Plasmodium falciparum orotidine 5'-phosphate decarboxylase covalently modified by 6-iodo-UMP 分子名称: Orotidine 5' monophosphate decarboxylase, SULFATE ION, URIDINE-5'-MONOPHOSPHATE 著者 Liu, Y, Lau, W, Bello, A.M, Kotra, L.P, Hui, R, Pai, E.F. 登録日 2007-06-15 公開日 2008-04-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase J.Med.Chem., 51, 2008
2QEX	Negamycin Binds to the Wall of the Nascent Chain Exit Tunnel of the 50S Ribosomal Subunit 分子名称: 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L11P, ... 著者 Schroeder, S.J, Blaha, G. 登録日 2007-06-26 公開日 2008-09-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit. Antimicrob.Agents Chemother., 51, 2007
2F6U	Crystal Structure of (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase complexed with citrate 分子名称: (S)-3-O-Geranylgeranylglyceryl Phosphate Synthase, CITRIC ACID 著者 Payandeh, J. 登録日 2005-11-29 公開日 2006-01-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme J.Biol.Chem., 281, 2006
2FDW	Crystal Structure Of Human Microsomal P450 2A6 with the inhibitor (5-(Pyridin-3-yl)furan-2-yl)methanamine bound 分子名称: (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE 著者 Yano, J.K, Stout, C.D, Johnson, E.F. 登録日 2005-12-14 公開日 2006-11-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization. J.Med.Chem., 49, 2006

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