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5CGY

Fab fragment of Chikungunya virus neutralizing human monoclonal antibody 4J21

Summary for 5CGY
Entry DOI10.2210/pdb5cgy/pdb
DescriptorHeavy Chain of Fab, Light Chain of Fab (3 entities in total)
Functional Keywordsantibody, fab, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains4
Total formula weight93609.97
Authors
Long, F.,Crowe, J.E.,Rossmann, M.G. (deposition date: 2015-07-09, release date: 2015-11-11, Last modification date: 2023-09-27)
Primary citationLong, F.,Fong, R.H.,Austin, S.K.,Chen, Z.,Klose, T.,Fokine, A.,Liu, Y.,Porta, J.,Sapparapu, G.,Akahata, W.,Doranz, B.J.,Crowe, J.E.,Diamond, M.S.,Rossmann, M.G.
Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.
Proc.Natl.Acad.Sci.USA, 112:13898-13903, 2015
Cited by
PubMed: 26504196
DOI: 10.1073/pnas.1515558112
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.07 Å)
Structure validation

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