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1AZV
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FAMILIAL ALS MUTANT G37R CUZNSOD (HUMAN)
分子名称: COPPER (II) ION, COPPER/ZINC SUPEROXIDE DISMUTASE, ZINC ION
著者Hart, P.J, Liu, H, Pellegrini, M, Nersissian, A.M, Gralla, E.B, Valentine, J.S, Eisenberg, D.
登録日1997-11-21
公開日1998-02-25
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis.
Protein Sci., 7, 1998
5YTO
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Crystal Structure of human Superoxide Dismutase I (hSOD1) in complex with a napthalene-catechol linked compound.
分子名称: 4-[(1~{R})-2-(naphthalen-2-ylmethylamino)-1-oxidanyl-ethyl]benzene-1,2-diol, GLYCEROL, PENTASULFIDE-SULFUR, ...
著者Padmanabhan, B, Manjula, R.
登録日2017-11-19
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Assessment of ligand binding at a site relevant to SOD1 oxidation and aggregation
FEBS Lett., 592, 2018
5YUL
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Native Structure of hSOD1 in P6322 space group
分子名称: Dihydrogen tetrasulfide, GLYCEROL, Superoxide dismutase [Cu-Zn], ...
著者Manjula, R, Padmanabhan, B.
登録日2017-11-22
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Assessment of ligand binding at a site relevant to SOD1 oxidation and aggregation
FEBS Lett., 592, 2018
3CQQ
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Human SOD1 G85R Variant, Structure II
分子名称: ACETYL GROUP, Superoxide dismutase [Cu-Zn], ZINC ION
著者Cao, X, Antonyuk, S, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J.
登録日2008-04-03
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
1SXN
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REDUCED BOVINE SUPEROXIDE DISMUTASE AT PH 5.0
分子名称: CALCIUM ION, COPPER (II) ION, CU, ...
著者Ferraroni, M, Rypniewski, W.R, Bruni, B, Orioli, P, Wilson, K.S, Mangani, S.
登録日1997-09-17
公開日1998-03-18
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic determination of reduced bovine superoxide dismutase at pH 5.0 and of anion binding to its active site.
J.Biol.Inorg.Chem., 3, 1998
2APS
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BU of 2aps by Molmil
CU/ZN SUPEROXIDE DISMUTASE FROM ACTINOBACILLUS PLEUROPNEUMONIAE
分子名称: COPPER (II) ION, PROTEIN (CU,ZN SUPEROXIDE DISMUTASE), ZINC ION
著者Forest, K.T, Langford, P.R, Kroll, J.S, Getzoff, E.D.
登録日1999-02-11
公開日1999-02-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cu,Zn superoxide dismutase structure from a microbial pathogen establishes a class with a conserved dimer interface.
J.Mol.Biol., 296, 2000
1UXM
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A4V mutant of human SOD1
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION
著者Hough, M.A, Grossmann, J.G, Antonyuk, S.V, Strange, R.W, Doucette, P.A, Rodriguez, J.A, Whitson, L.J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2004-02-26
公開日2004-03-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dimer Destabilization in Superoxide Dismutase May Result in Disease-Causing Properties: Structures of Motor Neuron Disease Mutants
Proc.Natl.Acad.Sci.USA, 101, 2004
1YAI
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X-RAY STRUCTURE OF A BACTERIAL COPPER,ZINC SUPEROXIDE DISMUTASE
分子名称: COPPER (II) ION, COPPER, ZINC SUPEROXIDE DISMUTASE, ...
著者Bourne, Y, Redford, S.M, Lo, T.P, Tainer, J.A, Getzoff, E.D.
登録日1996-02-03
公開日1997-08-20
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Novel dimeric interface and electrostatic recognition in bacterial Cu,Zn superoxide dismutase.
Proc.Natl.Acad.Sci.USA, 93, 1996
7XX3
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Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB)
分子名称: (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Padmanabhan, B, Unni, S.
登録日2022-05-28
公開日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS)
To Be Published
1SXC
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CRYSTAL STRUCTURE OF REDUCED BOVINE ERYTHROCYTE SUPEROXIDE DISMUTASE AT 1.9 ANGSTROMS RESOLUTION
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE, ZINC ION
著者Rypniewski, W.R, Mangani, S, Bruni, B, Orioli, P, Casati, M, Wilson, K.S.
登録日1995-03-17
公開日1995-06-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of reduced bovine erythrocyte superoxide dismutase at 1.9 A resolution.
J.Mol.Biol., 251, 1995
1SXA
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CRYSTAL STRUCTURE OF REDUCED BOVINE ERYTHROCYTE SUPEROXIDE DISMUTASE AT 1.9 ANGSTROMS RESOLUTION
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE, ZINC ION
著者Rypniewski, W.R, Mangani, S, Bruni, B, Orioli, P, Casati, M, Wilson, K.S.
登録日1995-03-17
公開日1995-06-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of reduced bovine erythrocyte superoxide dismutase at 1.9 A resolution.
J.Mol.Biol., 251, 1995
4BCZ
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BU of 4bcz by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form.
分子名称: SUPEROXIDE DISMUTASE [CU-ZN]
著者Saraboji, K, Awad, W, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T.
登録日2012-10-03
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Global Structural Motions from the Strain of a Single Hydrogen Bond.
Proc.Natl.Acad.Sci.USA, 110, 2013
6FFK
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Human apo-SOD1 bound to PtCl2(1R,2R-1,4-DACH
分子名称: PtCl2(1(R),2(R)-DACH), Superoxide dismutase [Cu-Zn]
著者Calderone, V, Nativi, C, Cantini, F, Di Cesare Mannelli, L.
登録日2018-01-08
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Interaction of Half Oxa-/Halfcis-Platin Complex with Human Superoxide Dismutase and Induced Reduction of Neurotoxicity.
ACS Med Chem Lett, 9, 2018
6Z4H
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A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 2 in P21 space group
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-25
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
3CQP
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BU of 3cqp by Molmil
Human SOD1 G85R Variant, Structure I
分子名称: COPPER (II) ION, MALONATE ION, Superoxide dismutase [Cu-Zn], ...
著者Cao, X, Antonyuk, S, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J.
登録日2008-04-03
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
6SPJ
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BU of 6spj by Molmil
A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 1
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Chantadul, V, Amporndanai, K, Wright, G, Antonyuk, S, Hasnain, S.
登録日2019-09-01
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy.
Commun Biol, 3, 2020
2WKO
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BU of 2wko by Molmil
Structure of metal loaded Pathogenic SOD1 Mutant G93A.
分子名称: COPPER (II) ION, IODIDE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S.V, Galaleldeen, A, Strange, R, Whitson, L, Narayana, N, Taylor, A, Schuermann, J.P, Holloway, S.P, Hasnain, S.S, Hart, P.J.
登録日2009-06-16
公開日2009-11-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Biophysical Properties of Metal-Free Pathogenic Sod1 Mutants A4V and G93A.
Arch.Biochem.Biophys., 492, 2009
5K02
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Structure of human SOD1 with T2D mutation
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Fay, J.M, Zhu, C, Cui, W, Ke, H, Dokholyan, N.V.
登録日2016-05-17
公開日2016-11-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation.
Structure, 24, 2016
1SRD
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BU of 1srd by Molmil
Three-dimensional structure of CU,ZN-superoxide dismutase from spinach at 2.0 Angstroms resolution
分子名称: COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION
著者Kitagawa, Y, Katsube, Y.
登録日1993-04-15
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of Cu,Zn-superoxide dismutase from spinach at 2.0 A resolution.
J.Biochem.(Tokyo), 109, 1991
6DTK
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BU of 6dtk by Molmil
Heterodimers of FALS mutant SOD enzyme
分子名称: COPPER (II) ION, MALONATE ION, Superoxide dismutase C111S/D83S-C111S HETERODIMER, ...
著者Streltsov, V.A, Nuttall, S.D, Ganio, K.E, Roberts, B.
登録日2018-06-17
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization of heterodimers of FALS mutant SOD enzyme
To Be Published
5J07
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Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P1/2
分子名称: Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn]
著者Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M.
登録日2016-03-27
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
3KM1
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ZINC-Reconstituted TOMATO CHLOROPLAST SUPEROXIDE DISMUTASE
分子名称: GLYCEROL, Superoxide dismutase [Cu-Zn], chloroplastic, ...
著者Galaleldeen, A, Taylor, A.B, Thomas, S.T, Hart, P.J.
登録日2009-11-09
公開日2010-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biophysical properties of tomato chloroplast sod
To be Published
1N18
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Thermostable mutant of Human Superoxide Dismutase, C6A, C111S
分子名称: COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Cardoso, R.M.F, Thayer, M.M, DiDonato, M, Lo, T.P, Bruns, C.K, Getzoff, E.D, Tainer, J.A.
登録日2002-10-16
公開日2002-11-27
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.
J.Mol.Biol., 324, 2002
1XTL
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Crystal structure of P104H mutant of SOD-like protein from Bacillus subtilis.
分子名称: COPPER (II) ION, Hypothetical superoxide dismutase-like protein yojM, ZINC ION
著者Calderone, V, Mangani, S, Banci, L, Benvenuti, M, Bertini, I, Viezzoli, M.S, Fantoni, A.
登録日2004-10-22
公開日2005-10-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献From an Inactive Prokaryotic SOD Homologue to an Active Protein through Site-Directed Mutagenesis.
J.Am.Chem.Soc., 127, 2005
1IBH
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X-RAY 3D STRUCTURE OF P.LEIOGNATHI CU,ZN SOD MUTANT M41I
分子名称: COPPER (II) ION, CU,ZN SUPEROXIDE DISMUTASE, ZINC ION
著者Stroppolo, M.E, Pesce, A, D'Orazio, M, O'Neill, P, Bordo, D, Rosano, C, Milani, M, Battistoni, A, Bolognesi, M, Desideri, A.
登録日2001-03-28
公開日2001-05-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Single mutations at the subunit interface modulate copper reactivity in Photobacterium leiognathi Cu,Zn superoxide dismutase.
J.Mol.Biol., 308, 2001

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