6FFK

Human apo-SOD1 bound to PtCl2(1R,2R-1,4-DACH

Summary for 6FFK

• Entry DOI: 10.2210/pdb6ffk/pdb
• Related: 3re0
• Descriptor: Superoxide dismutase [Cu-Zn], PtCl2(1(R),2(R)-DACH) (3 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 64822.87

Authors

Calderone, V.,Nativi, C.,Cantini, F.,Di Cesare Mannelli, L. (deposition date: 2018-01-08, release date: 2018-11-28, Last modification date: 2024-01-17)

• Primary citation: Cantini, F.,Calderone, V.,Di Cesare Mannelli, L.,Korsak, M.,Gonnelli, L.,Francesconi, O.,Ghelardini, C.,Banci, L.,Nativi, C.; Interaction of Half Oxa-/Halfcis-Platin Complex with Human Superoxide Dismutase and Induced Reduction of Neurotoxicity.; ACS Med Chem Lett, 9:1094-1098, 2018; PubMed: 30429951; DOI: 10.1021/acsmedchemlett.8b00199

Experimental method

X-RAY DIFFRACTION (1.94 Å)