6Z4H

A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 2 in P21 space group

This is a non-PDB format compatible entry.

Summary for 6Z4H

• Entry DOI: 10.2210/pdb6z4h/pdb
• Descriptor: Superoxide dismutase [Cu-Zn], ZINC ION, ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide, ... (5 entities in total)
• Functional Keywords: sod1, ebselen, motor neuron disease, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 32814.32

Authors

Amporndanai, K.,Hasnain, S.S. (deposition date: 2020-05-25, release date: 2020-09-16, Last modification date: 2024-01-24)

• Primary citation: Amporndanai, K.,Rogers, M.,Watanabe, S.,Yamanaka, K.,O'Neill, P.M.,Hasnain, S.S.; Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.; Ebiomedicine, 59:102980-102980, 2020; PubMed: 32862101; DOI: 10.1016/j.ebiom.2020.102980

Experimental method

X-RAY DIFFRACTION (1.95 Å)