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5K02

Structure of human SOD1 with T2D mutation

Summary for 5K02
Entry DOI10.2210/pdb5k02/pdb
DescriptorSuperoxide dismutase [Cu-Zn], COPPER (II) ION, ZINC ION, ... (4 entities in total)
Functional Keywordssod1, phosphomimetic mutation, oxidoreductase
Biological sourceHomo sapiens (Human)
Total number of polymer chains24
Total formula weight383292.00
Authors
Fay, J.M.,Zhu, C.,Cui, W.,Ke, H.,Dokholyan, N.V. (deposition date: 2016-05-17, release date: 2016-11-23, Last modification date: 2023-09-27)
Primary citationFay, J.M.,Zhu, C.,Proctor, E.A.,Tao, Y.,Cui, W.,Ke, H.,Dokholyan, N.V.
A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation.
Structure, 24:1898-1906, 2016
Cited by
PubMed: 27667694
DOI: 10.1016/j.str.2016.08.011
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.99 Å)
Structure validation

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