PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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8GH6	Bombyx mori R2 retrotransposon initiating target-primed reverse transcription 分子名称: 28S DNA bottom strand, 3' side, 5' side (priming strand), ... 著者 Wilkinson, M.E, Zhang, F. 登録日 2023-03-09 公開日 2023-04-05 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription. Science, 380, 2023
1B94	RESTRICTION ENDONUCLEASE ECORV WITH CALCIUM 分子名称: CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV 著者 Thomas, M.P, Halford, S.E, Brady, R.L. 登録日 1999-02-19 公開日 1999-02-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group. Nucleic Acids Res., 27, 1999
7NXV	Crystal structure of the complex of DNase I/G-actin/PPP1R15A_582-621 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... 著者 Yan, Y, Ron, D. 登録日 2021-03-19 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
4PQL	N-Terminal domain of DNA binding protein 分子名称: 1,2-ETHANEDIOL, Truncated replication protein RepA 著者 Schumacher, M.A, Chinnam, N, Tonthat, N.K. 登録日 2014-03-03 公開日 2014-06-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.444 Å) 主引用文献 Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein. Proc.Natl.Acad.Sci.USA, 111, 2014
7TC3	Human APE1 in the apo form 分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial 著者 Pidugu, L.S, Pozharski, E, Drohat, A.C. 登録日 2021-12-22 公開日 2022-12-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.252 Å) 主引用文献 Characterizing inhibitors of human AP endonuclease 1. Plos One, 18, 2023
7TC2	Human APE1 in complex with 5-nitroindole-2-carboxylic acid 分子名称: 1,2-ETHANEDIOL, 5-nitro-1H-indole-2-carboxylic acid, DI(HYDROXYETHYL)ETHER, ... 著者 Pidugu, L.S, Pozharski, E, Drohat, A.C. 登録日 2021-12-22 公開日 2022-12-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Characterizing inhibitors of human AP endonuclease 1. Plos One, 18, 2023
8GXV	Structure of a bacterial serpin Choloropin derived from Cholorobium limicola 分子名称: GLYCEROL, Proteinase inhibitor I4 serpin, ZINC ION 著者 Zhou, A, Xu, J. 登録日 2022-09-21 公開日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Climpin, a Novel Bacterial a Serpin inducing a Broad Range of Proteases and Regulated by Heparin and DNA. To Be Published
4I2J	Binary complex of mouse TdT with dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA nucleotidylexotransferase, ZINC ION 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2I	Binary complex of mouse TdT with AP5A 分子名称: BIS(ADENOSINE)-5'-PENTAPHOSPHATE, DNA nucleotidylexotransferase, MAGNESIUM ION, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
7UY5	Tetrahymena telomerase with CST 分子名称: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... 著者 He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. 登録日 2022-05-06 公開日 2022-07-13 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
7UY6	Tetrahymena telomerase at 2.9 Angstrom resolution 分子名称: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... 著者 He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. 登録日 2022-05-06 公開日 2022-07-13 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase. Nature, 608, 2022
6GTC	Transition state structure of Cpf1(Cas12a) I1 conformation 分子名称: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*G)-3'), DNA (5'-D(P*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ... 著者 Mesa, P, Montoya, G. 登録日 2018-06-18 公開日 2018-12-19 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. Cell, 175, 2018
6GTE	Transient state structure of CRISPR-Cpf1 (Cas12a) I3 conformation 分子名称: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*G)-3'), ... 著者 Montoya, G, Mesa, P, Stella, S. 登録日 2018-06-18 公開日 2018-12-19 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. Cell, 175, 2018
6GTG	Transition state structure of Cpf1(Cas12a) I4 conformation 分子名称: CRISPR-associated endonuclease Cas12a, DNA (32-MER), DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*GP*T)-3'), ... 著者 Mesa, P, Montoya, G, Stella, S. 登録日 2018-06-18 公開日 2018-12-19 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. Cell, 175, 2018
6GTF	Transient state structure of CRISPR-Cpf1 (Cas12a) I5 conformation 分子名称: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*A)-3'), ... 著者 Montoya, G, Mesa, P, Stella, S. 登録日 2018-06-18 公開日 2018-12-19 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.63 Å) 主引用文献 Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. Cell, 175, 2018
3E7L	Crystal structure of sigma54 activator NtrC4's DNA binding domain 分子名称: Transcriptional regulator (NtrC family), ZINC ION 著者 Batchelor, J.D, Doucleff, M, Lee, C.-J, Matsubara, K, De Carlo, S, Heideker, J, Lamers, M.M, Pelton, J.G, Wemmer, D.E. 登録日 2008-08-18 公開日 2008-11-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.252 Å) 主引用文献 Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation. J.Mol.Biol., 384, 2008
1LRP	COMPARISON OF THE STRUCTURES OF CRO AND LAMBDA REPRESSOR PROTEINS FROM BACTERIOPHAGE LAMBDA 分子名称: LAMBDA REPRESSOR 著者 Pabo, C, Lewis, M. 登録日 1987-12-04 公開日 1989-01-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Comparison of the structures of cro and lambda repressor proteins from bacteriophage lambda. J.Mol.Biol., 169, 1983
4MKW	Comparison of the structural and dynamic effects of 5-methylcytosine and 5-chlorocytosine in a CpG dinucleotide sequence 分子名称: 5methylC DNA dodecamer, MAGNESIUM ION 著者 Yin, Y.W. 登録日 2013-09-05 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.219 Å) 主引用文献 Comparison of the structural and dynamic effects of 5-methylcytosine and 5-chlorocytosine in a CpG dinucleotide sequence. Biochemistry, 52, 2013
7MI9	Full integration complex of Cas1/Cas2 from Cas4-containing system 分子名称: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (5'-D(P*CP*GP*GP*AP*AP*AP*AP*GP*AP*GP*CP*C)-3'), ... 著者 Hu, C.Y, Ke, A.K. 登録日 2021-04-16 公開日 2021-11-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.89 Å) 主引用文献 Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas. Nature, 598, 2021
7MIB	Half integration complex of Cas4/Cas1/Cas2 with Cas4 still on the Non-PAM side 分子名称: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (31-MER), ... 著者 Hu, C.Y, Ke, A.K. 登録日 2021-04-16 公開日 2021-11-17 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas. Nature, 598, 2021
3VA0	Crystal structure of RNase T in complex with a di-nucleotide product (GG) with one Mg in the active site 分子名称: COBALT (II) ION, DNA (5'-D(*GP*G)-3'), MAGNESIUM ION, ... 著者 Hsiao, Y.-Y, Yuan, H.S. 登録日 2011-12-28 公開日 2012-07-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes Nucleic Acids Res., 40, 2012
8HB2	Crystal structure of Caenorhabditis elegans NMAD-1 in complex with ligand II 分子名称: 2-OXOGLUTARIC ACID, DNA N6-methyl adenine demethylase, MANGANESE (II) ION 著者 Shang, G, Chen, Z. 登録日 2022-10-27 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A. Int J Mol Sci, 25, 2024
8HBB	Crystal structure of Caenorhabditis elegans NMAD-1 in complex with ligand III 分子名称: CHLORIDE ION, DNA N6-methyl adenine demethylase, MANGANESE (II) ION 著者 Shang, G, Chen, Z. 登録日 2022-10-27 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A. Int J Mol Sci, 25, 2024
8C8J	Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, CHLORIDE ION, ... 著者 Nichols, C.E, Walpole, T.B, Baldwin, E. 登録日 2023-01-20 公開日 2023-12-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626, 2024
3N5N	Crystal structure analysis of the catalytic domain and interdomain connector of human MutY homologue 分子名称: A/G-specific adenine DNA glycosylase, ACETATE ION, IRON/SULFUR CLUSTER 著者 Toth, E.A, Luncsford, P.J. 登録日 2010-05-25 公開日 2010-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. J.Mol.Biol., 403, 2010

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