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4GL5
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Structure of human placental aromatase complexed with designed inhibitor HDDG029 (compound 4)
分子名称: (6alpha,8alpha)-6-(but-2-yn-1-yloxy)androsta-1,4-diene-3,17-dione, Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE
著者Ghosh, D.
登録日2012-08-13
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
1TAQ
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BU of 1taq by Molmil
STRUCTURE OF TAQ DNA POLYMERASE
分子名称: 2-O-octyl-beta-D-glucopyranose, TAQ DNA POLYMERASE, ZINC ION
著者Kim, Y, Eom, S.H, Wang, J, Lee, D.-S, Suh, S.W, Steitz, T.A.
登録日1996-06-04
公開日1996-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of Thermus aquaticus DNA polymerase.
Nature, 376, 1995
3QU8
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BU of 3qu8 by Molmil
Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine.
分子名称: 4-(4-nitrobenzyl)pyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ...
著者Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R.
登録日2011-02-23
公開日2011-09-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains.
Mol.Pharmacol., 80, 2011
1TIK
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BU of 1tik by Molmil
CRYSTAL STRUCTURE OF ACYL CARRIER PROTEIN PHOSPHODIESTERASE
分子名称: Acyl carrier protein phosphodiesterase, SULFATE ION
著者Rajashankar, K.R, Kniewel, R, Solorzano, V, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2004-06-02
公開日2004-06-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献CRYSTAL STRUCTURE OF ACYL CARRIER PROTEIN PHOSPHODIESTERASE
To be Published
7M30
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BU of 7m30 by Molmil
Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25
分子名称: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain, 1-32 Fab Heavy Chain, ...
著者Wrapp, D, McLellan, J.S.
登録日2021-03-17
公開日2021-08-11
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M5U
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BU of 7m5u by Molmil
Crystal structure of human MPP8 chromodomain in complex with peptidomimetic ligand UNC5246
分子名称: M-phase phosphoprotein 8, UNC5246
著者Budziszewski, G.R, McGinty, R.K, Waybright, J.M, Norris, J.L, James, L.I.
登録日2021-03-24
公開日2021-09-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH Complex.
Acs Chem.Biol., 16, 2021
4G2G
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BU of 4g2g by Molmil
Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4,4'-(1H-1,2,3-triazole-1,5-diyl)diphenol
分子名称: 4,4'-(1H-1,2,3-triazole-1,5-diyl)diphenol, Cytochrome P450 121, DIMETHYL SULFOXIDE, ...
著者Hudson, S.A.
登録日2012-07-12
公開日2012-09-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121
Angew.Chem.Int.Ed.Engl., 51, 2012
7MSJ
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BU of 7msj by Molmil
The crystal structure of mouse HVEM
分子名称: SULFATE ION, Tumor necrosis factor receptor superfamily member 14
著者Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C.
登録日2021-05-11
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
J.Exp.Med., 218, 2021
7MSG
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BU of 7msg by Molmil
The crystal structure of LIGHT in complex with HVEM and CD160
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD160 antigen, soluble form,Tumor necrosis factor receptor superfamily member 14, ...
著者Liu, W, Ramagopal, U, Garrett-Thompson, S.C, Fedorov, E, Bonanno, J.B, Almo, S.C.
登録日2021-05-11
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
J.Exp.Med., 218, 2021
7MK7
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BU of 7mk7 by Molmil
Augmentor domain of augmentor-beta
分子名称: ALK and LTK ligand 1,Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Krimmer, S.G, Reshetnyak, A.V, Puleo, D.E, Schlessinger, J.
登録日2021-04-21
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.42815185 Å)
主引用文献Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
1RK6
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BU of 1rk6 by Molmil
The enzyme in complex with 50mM CdCl2
分子名称: ACETATE ION, CADMIUM ION, D-aminoacylase, ...
著者Lai, W.L, Chou, L.Y, Ting, C.Y, Tsai, Y.C, Liaw, S.H.
登録日2003-11-20
公開日2004-04-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
J.Biol.Chem., 279, 2004
1B74
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BU of 1b74 by Molmil
GLUTAMATE RACEMASE FROM AQUIFEX PYROPHILUS
分子名称: D-GLUTAMINE, GLUTAMATE RACEMASE
著者Hwang, K.Y, Cho, C.S, Kim, S.S, Yu, Y.G, Cho, Y.
登録日1999-01-27
公開日2000-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and mechanism of glutamate racemase from Aquifex pyrophilus.
Nat.Struct.Biol., 6, 1999
1RJR
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BU of 1rjr by Molmil
The crystal structure of the D-aminoacylase D366A mutant in complex with 100mM ZnCl2
分子名称: ACETATE ION, D-aminoacylase, ZINC ION
著者Lai, W.L, Chou, L.Y, Ting, C.Y, Tsai, Y.C, Liaw, S.H.
登録日2003-11-20
公開日2004-04-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
J.Biol.Chem., 279, 2004
4G1X
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BU of 4g1x by Molmil
Crystal structure of Mycobacterium tuberculosis CYP121 in complex with 4-(1H-1,2,4-triazol-1-yl)quinolin-6-amine
分子名称: 4-(1H-1,2,4-triazol-1-yl)quinolin-6-amine, Cytochrome P450 121, DIMETHYL SULFOXIDE, ...
著者Hudson, S.A.
登録日2012-07-11
公開日2012-09-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121
Angew.Chem.Int.Ed.Engl., 51, 2012
7MSL
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BU of 7msl by Molmil
Structure of anti-CRISPR AcrIIC4 from Haemophilus parainfluenzae
分子名称: AcrIIC4, IODIDE ION
著者Pan, C, Maxwell, K.L, Moraes, T.F.
登録日2021-05-11
公開日2022-03-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4 Hpa.
J.Mol.Biol., 434, 2022
4G48
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BU of 4g48 by Molmil
Structure of CYP121 in complex with 4-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-diol
分子名称: 4-(4-phenoxy-1H-pyrazol-3-yl)benzene-1,3-diol, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Hudson, S.A, McLean, K.J, Surade, S, Yang, Y.-Q, Leys, D, Ciulli, A, Munro, A.W, Abell, C.
登録日2012-07-16
公開日2012-09-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121
Angew.Chem.Int.Ed.Engl., 51, 2012
6AB5
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BU of 6ab5 by Molmil
Cryo-EM structure of T=1 Penaeus vannamei nodavirus
分子名称: Capsid protein
著者Chen, N.C, Miyazaki, N, Yoshimura, M, Guan, H.H, Lin, C.C, Iwasaki, K, Chen, C.J.
登録日2018-07-20
公開日2019-03-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism.
Commun Biol, 2, 2019
4G2N
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BU of 4g2n by Molmil
Crystal structure of putative D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding from Polaromonas sp. JS6 66
分子名称: CHLORIDE ION, D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding, ...
著者Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Zenchek, W, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-07-12
公開日2012-07-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of putative D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding from Polaromonas sp. JS6 66
To be Published
3QOA
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BU of 3qoa by Molmil
Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-Benzylpyridine.
分子名称: 4-benzylpyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ...
著者Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R.
登録日2011-02-09
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains.
Mol.Pharmacol., 80, 2011
7MNJ
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BU of 7mnj by Molmil
Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 145-673)
分子名称: E3 SUMO-protein ligase RanBP2
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Patke, A, Dasso, M, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNK
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BU of 7mnk by Molmil
Crystal structure of the tetramerization element of NUP358/RanBP2 (residues 805-832)
分子名称: 1,2-ETHANEDIOL, E3 SUMO-protein ligase RanBP2, SULFATE ION
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNO
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BU of 7mno by Molmil
Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) I656V mutant in complex with Fab fragment
分子名称: Antibody Fab14 Heavy Chain, Antibody Fab14 Light Chain, E3 SUMO-protein ligase RanBP2
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (6.73 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNL
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BU of 7mnl by Molmil
Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) in complex with Fab fragment
分子名称: Antibody Fab14 Heavy Chain, Antibody Fab14 Light Chain, E3 SUMO-protein ligase RanBP2
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNN
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BU of 7mnn by Molmil
Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) T653I mutant in complex with Fab fragment
分子名称: Antibody Fab14 Heavy Chain, Antibody Fab14 Light Chain, E3 SUMO-protein ligase RanBP2
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (6.7 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNI
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BU of 7mni by Molmil
Crystal structure of the N-terminal domain of NUP88 in complex with NUP98 C-terminal Autoproteolytic Domain
分子名称: Nuclear pore complex protein Nup88, Nuclear pore complex protein Nup98
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022

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