4ZFO
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![BU of 4zfo by Molmil](/molmil-images/mine/4zfo) | J22.9-xi: chimeric mouse/human antibody against human BCMA (CD269) | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, J22.9-xi Fab, ... | 著者 | Marino, S.F, Daumke, O, Olal, D. | 登録日 | 2015-04-21 | 公開日 | 2015-05-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma. Mol Oncol, 9, 2015
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5W08
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5WJX
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![BU of 5wjx by Molmil](/molmil-images/mine/5wjx) | Cryo-EM structure of B. subtilis flagellar filaments S17P | 分子名称: | Flagellin | 著者 | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | 登録日 | 2017-07-24 | 公開日 | 2017-10-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
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5HS7
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5WJV
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5WJW
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![BU of 5wjw by Molmil](/molmil-images/mine/5wjw) | Cryo-EM structure of B. subtilis flagellar filaments H84R | 分子名称: | Flagellin | 著者 | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | 登録日 | 2017-07-24 | 公開日 | 2017-10-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
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5HPR
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![BU of 5hpr by Molmil](/molmil-images/mine/5hpr) | Insulin with proline analog HyP at position B28 in the T2 state | 分子名称: | GLYCEROL, Insulin A-Chain, Insulin B-Chain, ... | 著者 | Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. | 登録日 | 2016-01-21 | 公開日 | 2017-01-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
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5AXI
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![BU of 5axi by Molmil](/molmil-images/mine/5axi) | Crystal structure of Cbl-b TKB domain in complex with Cblin | 分子名称: | CALCIUM ION, CHLORIDE ION, Cblin, ... | 著者 | Ohno, A, Maita, N, Ochi, A, Nakao, R, Nikawa, T. | 登録日 | 2015-07-29 | 公開日 | 2016-03-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of the TKB domain of ubiquitin ligase Cbl-b complexed with its small inhibitory peptide, Cblin Arch.Biochem.Biophys., 594, 2016
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8BYN
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![BU of 8byn by Molmil](/molmil-images/mine/8byn) | Chronic traumatic encephalopathy tau filaments with PET ligand flortaucipir | 分子名称: | 7-(6-fluoranylpyridin-3-yl)-5~{H}-pyrido[4,3-b]indole, Microtubule-associated protein tau | 著者 | Shi, Y, Ghetti, B, Goedert, M, Scheres, S.H.W. | 登録日 | 2022-12-13 | 公開日 | 2023-01-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir. J.Mol.Biol., 435, 2023
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7Z42
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6EDD
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![BU of 6edd by Molmil](/molmil-images/mine/6edd) | Crystal structure of a GNAT Superfamily PA3944 acetyltransferase in complex with CoA (P1 space group) | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Acetyltransferase PA3944, ... | 著者 | Czub, M.P, Porebski, P.J, Majorek, K.A, Satchell, K.J, Joachimiak, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-08-09 | 公開日 | 2018-08-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | A Gcn5-Related N-Acetyltransferase (GNAT) Capable of Acetylating Polymyxin B and Colistin Antibiotics in Vitro. Biochemistry, 57, 2018
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5INC
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![BU of 5inc by Molmil](/molmil-images/mine/5inc) | Crystal structure of HLA-B5801, a protective HLA allele for HIV-1 infection | 分子名称: | Beta-2-microglobulin, GLN-ALA-THR-GLN-GLU-VAL-LYS-ASN-TRP, HLA class I histocompatibility antigen, ... | 著者 | Li, X, Wang, J.-H. | 登録日 | 2016-03-07 | 公開日 | 2016-10-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.881 Å) | 主引用文献 | Crystal structure of HLA-B*5801, a protective HLA allele for HIV-1 infection. Protein Cell, 7, 2016
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8T9V
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![BU of 8t9v by Molmil](/molmil-images/mine/8t9v) | RTA-RUNT-59 complex structure | 分子名称: | (9aP)-7-fluoro-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid, NONAETHYLENE GLYCOL, Ricin | 著者 | Rudolph, M.J, Tumer, N. | 登録日 | 2023-06-26 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | 主引用文献 | Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin. Bioorg.Med.Chem., 100, 2024
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8TAD
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![BU of 8tad by Molmil](/molmil-images/mine/8tad) | RTA in complex with inhibitor RUNT-206 | 分子名称: | (9aM)-5,5-dimethyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid, CHLORIDE ION, NONAETHYLENE GLYCOL, ... | 著者 | Rudolph, M.J, Tumer, N. | 登録日 | 2023-06-27 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin. Bioorg.Med.Chem., 100, 2024
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8UM3
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![BU of 8um3 by Molmil](/molmil-images/mine/8um3) | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z203039992 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 6-chlorotetrazolo[1,5-b]pyridazine, ... | 著者 | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | 登録日 | 2023-10-17 | 公開日 | 2023-11-01 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (1.925 Å) | 主引用文献 | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z203039992 To Be Published
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6EUX
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5CDQ
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![BU of 5cdq by Molmil](/molmil-images/mine/5cdq) | 2.95A structure of Moxifloxacin with S.aureus DNA gyrase and DNA | 分子名称: | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*T*GP*GP*CP*CP*AP*TP*AP*CP*GP*CP*TP*T)-3'), DNA gyrase subunit A, ... | 著者 | Bax, B.D, Srikannathasan, V, Chan, P.F. | 登録日 | 2015-07-04 | 公開日 | 2015-12-16 | 最終更新日 | 2016-12-21 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin. Nat Commun, 6, 2015
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4YOA
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![BU of 4yoa by Molmil](/molmil-images/mine/4yoa) | Crsystal structure HIV-1 Protease MDR769 L33F Complexed with darunavir | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, HIV-1 Protease | 著者 | Kuiper, B.D, Keusch, B, Dewdney, T.G, Chordia, P, Brunzelle, J.S, Ross, K, Kovari, I.A, MacArthur, R, Salimnia, H, Kovari, L.C. | 登録日 | 2015-03-11 | 公開日 | 2015-07-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | 主引用文献 | The L33F darunavir resistance mutation acts as a molecular anchor reducing the flexibility of the HIV-1 protease 30s and 80s loops. Biochem Biophys Rep, 2, 2015
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7SO7
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3NW8
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![BU of 3nw8 by Molmil](/molmil-images/mine/3nw8) | Glycoprotein B from Herpes simplex virus type 1, Y179S mutant, high-pH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Stampfer, S.D, Lou, H, Cohen, G.H, Eisenberg, R.J, Heldwein, E.E. | 登録日 | 2010-07-09 | 公開日 | 2010-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.75915 Å) | 主引用文献 | Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. J.Virol., 84, 2010
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6B2E
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![BU of 6b2e by Molmil](/molmil-images/mine/6b2e) | Structure of full length human AMPK (a2b2g1) in complex with a small molecule activator SC4. | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | 著者 | Ngoei, K.R.W, Langendorf, C.G, Ling, N.X.Y, Hoque, A, Johnson, S, Camerino, M.C, Walker, S.R, Bozikis, Y.E, Dite, T.A, Ovens, A.J, Smiles, W.J, Jacobs, R, Huang, H, Parker, M.W, Scott, J.W, Rider, M.H, Kemp, B.E, Foitzik, R.C, Baell, J.B, Oakhill, J.S. | 登録日 | 2017-09-19 | 公開日 | 2018-04-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha 2 beta 2 gamma 1 by the Glucose Importagog SC4. Cell Chem Biol, 25, 2018
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6EVH
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8CSL
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![BU of 8csl by Molmil](/molmil-images/mine/8csl) | Sub-tomogram averaging of erythrocyte ankyrin-1 complex | 分子名称: | Ammonium transporter Rh type A, Ankyrin-1, Band 3 anion transport protein, ... | 著者 | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | 登録日 | 2022-05-12 | 公開日 | 2022-07-20 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (25 Å) | 主引用文献 | Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
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6B1U
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![BU of 6b1u by Molmil](/molmil-images/mine/6b1u) | Structure of full-length human AMPK (a2b1g1) in complex with a small molecule activator SC4 | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | 著者 | Ngoei, K.R.W, Langendorf, C.G, Ling, N.X.Y, Hoque, A, Johnson, S, Camerino, M.C, Walker, S.R, Bozikis, Y.E, Dite, T.A, Ovens, A.J, Smiles, W.J, Jacobs, R, Huang, H, Parker, M.W, Scott, J.W, Rider, M.H, Kemp, B.E, Foitzik, R.C, Baell, J.B, Oakhill, J.S. | 登録日 | 2017-09-19 | 公開日 | 2018-04-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK alpha 2 beta 2 gamma 1 by the Glucose Importagog SC4. Cell Chem Biol, 25, 2018
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8OWL
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![BU of 8owl by Molmil](/molmil-images/mine/8owl) | SR Ca(2+)-ATPase in the E2 state complexed with the photoswitch-thapsigargin derivative AzTG-6 | 分子名称: | ACETYL GROUP, SODIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, ... | 著者 | Hjorth-Jensen, S.J, Konrad, D.B, Quistgaard, E.M.H, Hansen, L.C, Novak, A, Chu, H, Jurasek, M, Zimmermann, T, Andersen, J.L, Baran, P.S, Nissen, P, Trauner, D. | 登録日 | 2023-04-28 | 公開日 | 2023-06-21 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Photoswitchable inhibitors of the sarco(endo)plasmic calcium pump To Be Published
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