8T9V
RTA-RUNT-59 complex structure
Summary for 8T9V
Entry DOI | 10.2210/pdb8t9v/pdb |
Descriptor | Ricin, (9aP)-7-fluoro-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxylic acid, NONAETHYLENE GLYCOL, ... (4 entities in total) |
Functional Keywords | n-glycosidase, inhibitors, toxin |
Biological source | Ricinus communis (castor bean) |
Total number of polymer chains | 1 |
Total formula weight | 29598.39 |
Authors | |
Primary citation | Rudolph, M.J.,Dutta, A.,Tsymbal, A.M.,McLaughlin, J.E.,Chen, Y.,Davis, S.A.,Theodorous, S.A.,Pierce, M.,Algava, B.,Zhang, X.,Szekely, Z.,Roberge, J.Y.,Li, X.P.,Tumer, N.E. Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin. Bioorg.Med.Chem., 100:117614-117614, 2024 Cited by PubMed: 38340640DOI: 10.1016/j.bmc.2024.117614 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.945 Å) |
Structure validation
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