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7U47
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BU of 7u47 by Molmil
CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and palindromic alpha satellite DNA sequence
分子名称: Centromere protein N, DNA (147-MER), Histone H2A, ...
著者Zhou, K, Luger, K.
登録日2022-02-28
公開日2022-03-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献CENP-N promotes the compaction of centromeric chromatin.
Nat.Struct.Mol.Biol., 29, 2022
8GOB
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BU of 8gob by Molmil
Crystal Structure of Glycerol Dehydrogenase in the presence of NAD+
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycerol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Park, T, Hoang, H.N, Kang, J.Y, Park, J, Mun, S.A, Jin, M, Yang, J, Jung, C.-H, Eom, S.H.
登録日2022-08-24
公開日2023-06-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and functional insights into the flexible beta-hairpin of glycerol dehydrogenase.
Febs J., 290, 2023
8GZU
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BU of 8gzu by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2
分子名称: 2 iron, 2 sulfur cluster-binding protein, 2-oxoglutarate/malate carrier protein, ...
著者Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
登録日2022-09-27
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (4.18 Å)
主引用文献Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
8GOA
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BU of 8goa by Molmil
Crystal Structure of Glycerol Dehydrogenase in the absence of NAD+
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycerol dehydrogenase, ZINC ION
著者Park, T, Hoang, H.N, Kang, J.Y, Park, J, Mun, S.A, Jin, M, Yang, J, Jung, C.-H, Eom, S.H.
登録日2022-08-24
公開日2023-06-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and functional insights into the flexible beta-hairpin of glycerol dehydrogenase.
Febs J., 290, 2023
8GYM
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BU of 8gym by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
著者Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
登録日2022-09-23
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
7R9W
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BU of 7r9w by Molmil
LC3A in complex with Fragment 1-1
分子名称: 4-phenoxybenzoic acid, GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3A
著者Rouge, L, Steffek, M, Helgason, E, Dueber, E, Mulvihill, M.
登録日2021-06-29
公開日2022-01-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands.
Biochemistry, 62, 2023
7R9Z
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BU of 7r9z by Molmil
LC3A in complex with Fragment 2-3
分子名称: (5-fluoro-1H-indol-3-yl)acetic acid, Microtubule-associated proteins 1A/1B light chain 3A
著者Rouge, L, Steffek, M, Helgason, E, Dueber, E, Mulvihill, M.
登録日2021-06-29
公開日2022-01-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands.
Biochemistry, 62, 2023
7RA0
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BU of 7ra0 by Molmil
LC3A in complex with Fragment 2-10
分子名称: (5-ethyl-2-methyl-1H-indol-3-yl)acetic acid, Microtubule-associated proteins 1A/1B light chain 3A
著者Rouge, L, Steffek, M, Helgason, E, Dueber, E, Mulvihill, M.
登録日2021-06-29
公開日2022-01-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands.
Biochemistry, 62, 2023
8GK3
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BU of 8gk3 by Molmil
Cytochrome P450 3A7 in complex with Dehydroepiandrosterone sulfate
分子名称: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Cytochrome P450 3A7, PROTOPORPHYRIN IX CONTAINING FE
著者Liu, J, Scott, E.E.
登録日2023-03-16
公開日2023-07-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate.
J.Biol.Chem., 299, 2023
6NSV
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BU of 6nsv by Molmil
Crystal structure of the human CHIP TPR domain in complex with a 5mer acetylated optimized peptide
分子名称: ACE-LEU-TRP-TRP-PRO-ASP, CHLORIDE ION, E3 ubiquitin-protein ligase CHIP, ...
著者Basu, K, Ravalin, M, Bohn, M.-F, Craik, C.S, Gestwicki, J.E.
登録日2019-01-25
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.305 Å)
主引用文献Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases.
Nat.Chem.Biol., 15, 2019
6NRB
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BU of 6nrb by Molmil
hTRiC-hPFD Class2
分子名称: Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ...
著者Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J.
登録日2019-01-23
公開日2019-06-19
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (8.7 Å)
主引用文献The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
6N3X
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BU of 6n3x by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[1-Benzyl]Carbamoyl Guanosine
分子名称: 1,2-ETHANEDIOL, 5'-O-(benzylcarbamoyl)guanosine, CHLORIDE ION, ...
著者Strom, A.M, Finzel, B.C.
登録日2018-11-16
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice.
Acs Chem Neurosci, 10, 2019
5NT0
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BU of 5nt0 by Molmil
Crystal structure of TNKS2 in complex with 2-(3-aminophenyl)-3,4-dihydroquinazolin-4-one
分子名称: 2-(3-aminophenyl)-3~{H}-quinazolin-4-one, GLYCEROL, SULFATE ION, ...
著者Nkizinkiko, Y, Haikarainen, T, Lehtio, L.
登録日2017-04-27
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Sci Rep, 8, 2018
5NVE
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BU of 5nve by Molmil
Crystal structure of TNKS2 in complex with 2-(4-ethoxyphenyl)-3,4-dihydroquinazolin-4-one
分子名称: 2-(4-ethoxyphenyl)-3~{H}-quinazolin-4-one, GLYCEROL, SULFATE ION, ...
著者Nkizinkiko, Y, Haikarainen, T, Lehtio, L.
登録日2017-05-04
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Sci Rep, 8, 2018
5NWB
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BU of 5nwb by Molmil
Crystal structure of TNKS2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one
分子名称: 2-[4-[2-hydroxyethyl(methyl)amino]phenyl]-3~{H}-quinazolin-4-one, GLYCEROL, SULFATE ION, ...
著者Nkizinkiko, Y, Haikarainen, T, Lehtio, L.
登録日2017-05-05
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Sci Rep, 8, 2018
5NW5
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BU of 5nw5 by Molmil
Crystal structure of the Rif1 N-terminal domain (RIF1-NTD) from Saccharomyces cerevisiae in complex with DNA
分子名称: DNA (30-MER), DNA (60-MER), Telomere length regulator protein RIF1
著者Bunker, R.D, Reinert, J.K, Shi, T, Thoma, N.H.
登録日2017-05-05
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (6.502 Å)
主引用文献Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends.
Nat. Struct. Mol. Biol., 24, 2017
6NBY
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BU of 6nby by Molmil
T.elongatus NDH (composite model)
分子名称: IRON/SULFUR CLUSTER, NAD(P)H-quinone oxidoreductase chain 4 1, NAD(P)H-quinone oxidoreductase subunit 1, ...
著者Laughlin, T.G, Bayne, A, Trempe, J.-F, Savage, D.F, Davies, K.M.
登録日2018-12-10
公開日2019-02-27
最終更新日2020-04-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the complex I-like molecule NDH of oxygenic photosynthesis.
Nature, 566, 2019
5NXE
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BU of 5nxe by Molmil
Crystal structure of TNKS2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-1,2,3,4-tetrahydroquinazolin-4-one
分子名称: 2-[4-[2-hydroxyethyl(methyl)amino]phenyl]-2,3-dihydro-1~{H}-quinazolin-4-one, GLYCEROL, SULFATE ION, ...
著者Nkizinkiko, Y, Haikarainen, T, Lehtio, L.
登録日2017-05-10
公開日2018-03-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Sci Rep, 8, 2018
5NWC
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BU of 5nwc by Molmil
Crystal structure of TNKS2 in complex with 2-(2-aminophenyl)-3,4-dihydroquinazolin-4-one
分子名称: 2-(2-aminophenyl)-3~{H}-quinazolin-4-one, GLYCEROL, SULFATE ION, ...
著者Nkizinkiko, Y, Haikarainen, T, Lehtio, L.
登録日2017-05-05
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors.
Sci Rep, 8, 2018
5NZZ
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BU of 5nzz by Molmil
Crystal structure of phosphorylated p38aMAPK in complex with TAB1
分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 14, NICKEL (II) ION, ...
著者Nichols, C.E, De Nicola, G.F.
登録日2017-05-15
公開日2018-05-30
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The TAB1-p38 alpha complex aggravates myocardial injury and can be targeted by small molecules.
JCI Insight, 3, 2018
7U4D
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BU of 7u4d by Molmil
CryoEM structure of CENP-N promoted nucleosome stacks with CENP-A and 601 DNA sequence
分子名称: Centromere protein N, DNA (147-MER), Histone H2A, ...
著者Zhou, K, Luger, K.
登録日2022-02-28
公開日2022-03-30
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献CENP-N promotes the compaction of centromeric chromatin.
Nat.Struct.Mol.Biol., 29, 2022
7U97
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BU of 7u97 by Molmil
SAAV pH 4.0 capsid structure
分子名称: Capsid protein
著者Mietzsch, M, McKenna, R.
登録日2022-03-10
公開日2022-04-13
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
7U95
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BU of 7u95 by Molmil
SAAV pH 6.0 capsid structure
分子名称: Capsid protein
著者Mietzsch, M, McKenna, R.
登録日2022-03-10
公開日2022-04-13
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
7U96
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SAAV pH 5.5 capsid structure
分子名称: Capsid protein
著者Mietzsch, M, McKenna, R.
登録日2022-03-10
公開日2022-04-13
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.14 Å)
主引用文献Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
7U94
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SAAV pH 7.4 capsid structure
分子名称: Capsid protein
著者Mietzsch, M, McKenna, R.
登録日2022-03-10
公開日2022-04-13
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022

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