7RA0

LC3A in complex with Fragment 2-10

Summary for 7RA0

Entry DOI	10.2210/pdb7ra0/pdb
Descriptor	Microtubule-associated proteins 1A/1B light chain 3A, (5-ethyl-2-methyl-1H-indol-3-yl)acetic acid (3 entities in total)
Functional Keywords	matg8, autophagy, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	14724.93
Authors	Rouge, L.,Steffek, M.,Helgason, E.,Dueber, E.,Mulvihill, M. (deposition date: 2021-06-29, release date: 2022-01-12, Last modification date: 2023-10-25)
Primary citation	Steffek, M.,Helgason, E.,Popovych, N.,Rouge, L.,Bruning, J.M.,Li, K.S.,Burdick, D.J.,Cai, J.,Crawford, T.,Xue, J.,Decurtins, W.,Fang, C.,Grubers, F.,Holliday, M.J.,Langley, A.,Petersen, A.,Satz, A.L.,Song, A.,Stoffler, D.,Strebel, Q.,Tom, J.Y.K.,Skelton, N.,Staben, S.T.,Wichert, M.,Mulvihill, M.M.,Dueber, E.C. A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands. Biochemistry, 62:633-644, 2023 Cited by PubMed: 34985287 DOI: 10.1021/acs.biochem.1c00682 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.36 Å)

Structure validation