8GK3

Cytochrome P450 3A7 in complex with Dehydroepiandrosterone sulfate

Summary for 8GK3

Entry DOI	10.2210/pdb8gk3/pdb
Descriptor	Cytochrome P450 3A7, PROTOPORPHYRIN IX CONTAINING FE, 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, ... (4 entities in total)
Functional Keywords	monooxygenase, oxidoreductase
Biological source	Homo sapiens (human)
Total number of polymer chains	12
Total formula weight	680805.44
Authors	Liu, J.,Scott, E.E. (deposition date: 2023-03-16, release date: 2023-07-26, Last modification date: 2023-08-30)
Primary citation	Liu, J.,Kandel, S.E.,Lampe, J.N.,Scott, E.E. Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate. J.Biol.Chem., 299:104993-104993, 2023 Cited by PubMed: 37392852 DOI: 10.1016/j.jbc.2023.104993 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation