8GK3
Cytochrome P450 3A7 in complex with Dehydroepiandrosterone sulfate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Cytochrome P450 3A7 | polymer | 486 | 55380.3 | 12 | UniProt (P24462) Pfam (PF00067) In PDB | Homo sapiens (human) | CYPIIIA7,Cytochrome P450-HFLA,P450HLp2 |
2 | E, F, G, H, A... | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 12 | Chemie (HEM) | |||
3 | D, E, H, A, I... | 17-oxoandrost-5-en-3beta-yl hydrogen sulfate | non-polymer | 368.5 | 24 | Chemie (ZWY) | |||
4 | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 24 - 503 (UniProt: P24462)
PDB | External Database | Details |
---|---|---|
Met 22 | - | initiating methionine |
Ala 23 | - | expression tag |
Gly 69 | Arg 69 | conflict |
Gly 77 | Cys 77 | conflict |
Glu 244 | Lys 244 | conflict |
Ala 421 | Lys 421 | conflict |
Ala 422 | Lys 422 | conflict |
Ala 424 | Lys 424 | conflict |
His 504 | - | expression tag |
His 505 | - | expression tag |
His 506 | - | expression tag |
His 507 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 664563.9 | |
Non-Polymers* | Number of molecules | 36 |
Total formula weight | 16241.6 | |
All* | Total formula weight | 680805.4 |