8TYO
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8TYL
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5WCM
| Crystal structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide - new refinement | 分子名称: | 4-nitrobenzenesulfonamide, Blr6230 protein, ZINC ION | 著者 | Docquier, J.D, Benvenuti, M, Calderone, V, Menciassi, N, Shabalin, I.G, Raczynska, J.E, Wlodawer, A, Jaskolski, M, Minor, W, Mangani, S. | 登録日 | 2017-06-30 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. Antimicrob. Agents Chemother., 54, 2010
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8S9V
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4UI0
| Crystal structure of the human RGMB-BMP2 complex, crystal form 2 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, BONE MORPHOGENETIC PROTEIN 2, CHLORIDE ION, ... | 著者 | Healey, E.G, Bishop, B, Elegheert, J, Bell, C.H, Padilla-Parra, S, Siebold, C. | 登録日 | 2015-03-27 | 公開日 | 2015-05-06 | 最終更新日 | 2015-06-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein. Nat.Struct.Mol.Biol., 22, 2015
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8S9X
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8SKT
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4UPJ
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8S9T
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8U0P
| Synaptic complex of human DNA polymerase Lambda DL variant engaged on a noncomplementary DNA double-strand break | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... | 著者 | Kaminski, A.M, Pedersen, L.C, Bebenek, K, Kunkel, T.A, Chiruvella, K.K, Ramsden, D.A. | 登録日 | 2023-08-29 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | DNA polymerase lambda Loop1 variant yields unexpected gain-of-function capabilities in nonhomologous end-joining. DNA Repair (Amst), 136, 2024
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4UMV
| CRYSTAL STRUCTURE OF A ZINC-TRANSPORTING PIB-TYPE ATPASE IN THE E2P STATE | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ZINC-TRANSPORTING ATPASE | 著者 | Wang, K.T, Sitsel, O, Meloni, G, Autzen, H.E, Andersson, M, Klymchuk, T, Nielsen, A.M, Rees, D.C, Nissen, P, Gourdon, P. | 登録日 | 2014-05-21 | 公開日 | 2014-08-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure and Mechanism of Zn(2+)-Transporting P-Type Atpases. Nature, 514, 2014
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4UEA
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4UC7
| N-terminal globular domain of the RSV Nucleoprotein | 分子名称: | NUCLEOPROTEIN, SULFATE ION | 著者 | Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S. | 登録日 | 2014-12-03 | 公開日 | 2015-08-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus. J.Virol., 89, 2015
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8S4S
| PrgE from plasmid pCF10 | 分子名称: | POTASSIUM ION, PrgE, SULFATE ION | 著者 | Breidenstein, A, Berntsson, R.P.-A. | 登録日 | 2024-02-22 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | PrgE: an OB-fold protein from plasmid pCF10 with striking differences to prototypical bacterial SSBs. Life Sci Alliance, 7, 2024
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4D89
| Crystal Structure of Human Beta Secretase in Complex with NVP-BXD552, derived from a soaking experiment | 分子名称: | (3S,4S,5R)-3-(4-amino-3-{[(2R)-3-ethoxy-1,1,1-trifluoropropan-2-yl]oxy}-5-fluorobenzyl)-5-[(3-tert-butylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1,1-dioxide, Beta-secretase 1 | 著者 | Rondeau, J.M, Bourgier, E. | 登録日 | 2012-01-10 | 公開日 | 2012-11-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery of cyclic sulfone hydroxyethylamines as potent and selective beta-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid beta-peptides J.Med.Chem., 55, 2012
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4UMW
| CRYSTAL STRUCTURE OF A ZINC-TRANSPORTING PIB-TYPE ATPASE IN E2.PI STATE | 分子名称: | MAGNESIUM ION, TETRAFLUOROALUMINATE ION, ZINC-TRANSPORTING ATPASE | 著者 | Wang, K.T, Sitsel, O, Meloni, G, Autzen, H.E, Andersson, M, Klymchuk, T, Nielsen, A.M, Rees, D.C, Nissen, P, Gourdon, P. | 登録日 | 2014-05-21 | 公開日 | 2014-08-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.705 Å) | 主引用文献 | Structure and Mechanism of Zn(2+)-Transporting P-Type Atpases. Nature, 514, 2014
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4V5Z
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8T5L
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8T5K
| Crystal structure of STING CTD in complex with BDW-OH | 分子名称: | Stimulator of interferon genes protein, {[(4S)-8,9-dimethylthieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidin-3-yl]sulfanyl}acetic acid | 著者 | Li, Y, Li, P, Sun, D. | 登録日 | 2023-06-13 | 公開日 | 2023-07-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING A230 Variants. Biorxiv, 2023
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2TSC
| STRUCTURE, MULTIPLE SITE BINDING, AND SEGMENTAL ACCOMODATION IN THYMIDYLATE SYNTHASE ON BINDING D/UMP AND AN ANTI-FOLATE | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | 著者 | Montfort, W.R, Stroud, R.M. | 登録日 | 1991-07-03 | 公開日 | 1991-10-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate. Biochemistry, 29, 1990
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7KZX
| Cryo-EM structure of YiiP-Fab complex in Apo state | 分子名称: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain | 著者 | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | 登録日 | 2020-12-10 | 公開日 | 2021-01-06 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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7KZZ
| Cryo-EM structure of YiiP-Fab complex in Holo state | 分子名称: | Cadmium and zinc efflux pump FieF, Fab2R heavy chain, Fab2R light chain, ... | 著者 | Lopez-Redondo, M.L, Fan, S, Koide, A, Koide, S, Beckstein, O, Stokes, D.L. | 登録日 | 2020-12-10 | 公開日 | 2021-01-06 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP. J.Gen.Physiol., 153, 2021
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4V99
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4W5R
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4W5Q
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