5WCM
Crystal structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide - new refinement
Replaces: 3M8TSummary for 5WCM
Entry DOI | 10.2210/pdb5wcm/pdb |
Descriptor | Blr6230 protein, ZINC ION, 4-nitrobenzenesulfonamide, ... (4 entities in total) |
Functional Keywords | hydrolase, zinc enzyme, sulfonamide complex, hydrolase-inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) |
Total number of polymer chains | 2 |
Total formula weight | 58559.50 |
Authors | Docquier, J.D.,Benvenuti, M.,Calderone, V.,Menciassi, N.,Shabalin, I.G.,Raczynska, J.E.,Wlodawer, A.,Jaskolski, M.,Minor, W.,Mangani, S. (deposition date: 2017-06-30, release date: 2017-07-19, Last modification date: 2023-10-04) |
Primary citation | Docquier, J.D.,Benvenuti, M.,Calderone, V.,Stoczko, M.,Menciassi, N.,Rossolini, G.M.,Mangani, S. High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. Antimicrob. Agents Chemother., 54:4343-4351, 2010 Cited by PubMed: 20696874DOI: 10.1128/AAC.00409-10 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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