PDB: 45176 件ウェブページステータス検索Chemie searchBIRD

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6XHW	Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.50A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S. 登録日 2020-06-19 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nat.Chem.Biol., 17, 2021
6XR8	Distinct conformational states of SARS-CoV-2 spike protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zhang, J, Cai, Y.F, Xiao, T.S, Peng, H.Q, Sterling, S.M, Walsh Jr, R.M, Rawson, S, Volloch, S.R, Chen, B. 登録日 2020-07-11 公開日 2020-07-22 最終更新日 2020-11-25 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Distinct conformational states of SARS-CoV-2 spike protein. Science, 369, 2020
5A56	The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with 1-O-methyl-T-antigen 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CITRIC ACID, ... 著者 Gregg, K.J, Suits, M.D.L, Deng, L, Vocadlo, D.J, Boraston, A.B. 登録日 2015-06-16 公開日 2015-09-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism. J.Biol.Chem., 290, 2015
6XVG	Human Sirt6 3-318 in complex with ADP-ribose and the activator MDL-801 分子名称: 5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid, GLYCEROL, NAD-dependent protein deacetylase sirtuin-6, ... 著者 You, W, Steegborn, C. 登録日 2020-01-22 公開日 2020-10-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Binding site for activator MDL-801 on SIRT6. Nat.Chem.Biol., 17, 2021
5AA5	Actinobacterial-type NiFe-hydrogenase from Ralstonia eutropha H16 at 2.85 Angstrom resolution 分子名称: IRON/SULFUR CLUSTER, MALONIC ACID, NIFE-HYDROGENASE LARGE SUBUNIT, ... 著者 Schaefer, C, Bommer, M, Hennig, S, Jeoung, J.H, Dobbek, H, Lenz, O. 登録日 2015-07-23 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.497 Å) 主引用文献 Structure of an Actinobacterial-Type [Nife]-Hydrogenase Reveals Insight Into O2-Tolerant H2 Oxidation. Structure, 24, 2016
6XRT	Cryo-EM structure of SHIV-elicited RHA1.V2.01 in complex with HIV-1 Env BG505 DS-SOSIP.664 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Gorman, J, Kwong, P.D. 登録日 2020-07-13 公開日 2020-10-07 最終更新日 2021-01-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science, 371, 2021
5A8K	METHYL-COENZYME M REDUCTASE FROM METHANOTHERMOBACTER WOLFEII AT 1.4 A RESOLUTION 分子名称: 1-THIOETHANESULFONIC ACID, 2-ETHOXYETHANOL, CALCIUM ION, ... 著者 Wagner, T, Ermler, U. 登録日 2015-07-16 公開日 2016-08-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Didehydroaspartate Modification in Methyl-Coenzyme M Reductase Catalyzing Methane Formation. Angew.Chem.Int.Ed.Engl., 55, 2016
6XB3	Structure of AcNPV poxin in post-reactive state with Gp[2'-5']Ap[3'] 分子名称: 2',5'-GpAp, Poxin 著者 Eaglesham, J.B, McCarty, K.L, Kranzusch, P.J. 登録日 2020-06-05 公開日 2020-11-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict. Elife, 9, 2020
6XV6	Human Sirt6 3-318 in complex with ADP-ribose 分子名称: GLYCEROL, NAD-dependent protein deacetylase sirtuin-6, NICOTINAMIDE, ... 著者 You, W, Steegborn, C. 登録日 2020-01-21 公開日 2020-10-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Binding site for activator MDL-801 on SIRT6. Nat.Chem.Biol., 17, 2021
4ZUX	SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome 分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Morgan, M, Wolberger, C. 登録日 2015-05-17 公開日 2016-02-24 最終更新日 2016-03-09 実験手法 X-RAY DIFFRACTION (3.82 Å) 主引用文献 Structural basis for histone H2B deubiquitination by the SAGA DUB module. Science, 351, 2016
6XDR	Escherichia coli transcription-translation complex B (TTC-B) containing an 27 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... 著者 Molodtsov, V, Wang, C, Su, M, Ebright, R.H. 登録日 2020-06-11 公開日 2020-09-02 最終更新日 2020-09-23 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structural basis of transcription-translation coupling. Science, 369, 2020
6XXI	Crystal Structure of Human Deoxyhypusine Synthase in complex with NAD 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Wator, E, Wilk, P, Grudnik, P. 登録日 2020-01-27 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.679 Å) 主引用文献 Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
4XYJ	Crystal structure of human phosphofructokinase-1 in complex with ATP and Mg, Northeast Structural Genomics Consortium Target HR9275 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent 6-phosphofructokinase, platelet type, ... 著者 Forouhar, F, Webb, B.A, Szu, F.-E, Seetharaman, J, Barber, D.L, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2015-02-02 公開日 2015-05-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature, 523, 2015
5A03	Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with xylose 分子名称: 1,4-DIETHYLENE DIOXIDE, ALDOSE-ALDOSE OXIDOREDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Taberman, H, Rouvinen, J, Parkkinen, T. 登録日 2015-04-17 公開日 2015-10-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.848 Å) 主引用文献 Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase. Biochem.J., 472, 2015
4ZYQ	X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10s 分子名称: CARBONATE ION, N-{(1R)-2-(hydroxyamino)-1-[3'-(N'-hydroxycarbamimidoyl)biphenyl-4-yl]-2-oxoethyl}-2,2-dimethylpropanamide, PENTAETHYLENE GLYCOL, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-22 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
6XIQ	Cryo-EM Structure of K63R Ubiquitin Mutant Ribosome under Oxidative Stress 分子名称: 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Zhou, Y, Bartesaghi, A, Silva, G.M. 登録日 2020-06-21 公開日 2020-08-26 最終更新日 2020-09-23 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
6XXK	Crystal Structure of Human Deoxyhypusine Synthase in complex with spermidine 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Wator, E, Wilk, P, Grudnik, P. 登録日 2020-01-27 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase. Biomolecules, 10, 2020
6XZB	E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification). 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L. 登録日 2020-02-03 公開日 2020-11-04 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.54 Å) 主引用文献 Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome. Rna, 26, 2020
5AEW	Crystal structure of II9 variant of Biphenyl dioxygenase from Burkholderia xenovorans LB400 in complex with biphenyl 分子名称: BIPHENYL, BIPHENYL DIOXYGENASE SUBUNIT ALPHA, BIPHENYL DIOXYGENASE SUBUNIT BETA, ... 著者 Dhindwal, S, Gomez-Gil, L, Sylvestre, M, Eltis, L.D, Bolin, J.T, Kumar, P. 登録日 2015-01-10 公開日 2016-04-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural Basis of the Enhanced Pollutant-Degrading Capabilities of an Engineered Biphenyl Dioxygenase. J.Bacteriol., 198, 2016
5A6V	Open and closed conformations and protonation states of Candida antarctica Lipase B: Xenon complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ISOPROPYL ALCOHOL, LIPASE B, ... 著者 Stauch, B, Fisher, S.J, Cianci, M. 登録日 2015-07-01 公開日 2015-10-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Open and Closed States of Candida Antarctica Lipase B: Protonation and the Mechanism of Interfacial Activation. J.Lipid Res., 56, 2015
5A7M	The structure of Hypocrea jecorina beta-xylosidase Xyl3A (Bxl1) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Mikkelsen, N.E, Gudmundsson, M, Karkehabadi, S, Hansson, H, Sandgren, M, Larenas, E, Mitchinson, C, Keleman, B, Kaper, T. 登録日 2015-07-08 公開日 2016-08-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Th Crystal Structure of a Fungal Glycoside Hydrolase Family 3 Beta-Xylosidase, Xyl3A from Hypocrea Jecorina To be Published
5A8M	Crystal structure of the selenomethionine derivative of beta-glucanase SdGluc5_26A from Saccharophagus degradans 分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... 著者 Sulzenbacher, G, Lafond, M, Freyd, T, Henrissat, B, Coutinho, R.M, Berrin, J.G, Garron, M.L. 登録日 2015-07-16 公開日 2016-01-20 最終更新日 2017-09-13 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 The Quaternary Structure of a Glycoside Hydrolase Dictates Specificity Towards Beta-Glucans J.Biol.Chem., 291, 2016
4ZY0	X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10q 分子名称: CARBONATE ION, GLYCEROL, N-{(1R)-2-(hydroxyamino)-2-oxo-1-[4-(thiophen-3-yl)phenyl]ethyl}-2,2-dimethylpropanamide, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-21 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
4ZY2	X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10o 分子名称: CARBONATE ION, DIMETHYL SULFOXIDE, N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluorobiphenyl-4-yl)ethyl]-2,2-dimethylpropanamide, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-21 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
5A13	Crystal structure of Chlorite Dismutase from Magnetospirillum sp. in complex with thiocyanate 分子名称: CHLORITE DISMUTASE, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Correia, H.D, Santos-Silva, T. 登録日 2015-04-27 公開日 2015-09-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Ligand Binding to Chlorite Dismutase from Magnetospirillum Sp. J.Phys.Chem.B, 119, 2015

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