6XB3
Structure of AcNPV poxin in post-reactive state with Gp[2'-5']Ap[3']
Summary for 6XB3
Entry DOI | 10.2210/pdb6xb3/pdb |
Descriptor | Poxin, 2',5'-GpAp (3 entities in total) |
Functional Keywords | poxin, p26, baculovirus, nucleopolyhedrovirus, innate immunity, nuclease, cgas, cgamp, sting, hydrolase |
Biological source | Autographa californica nuclear polyhedrosis virus (AcMNPV) |
Total number of polymer chains | 16 |
Total formula weight | 449470.70 |
Authors | Eaglesham, J.B.,McCarty, K.L.,Kranzusch, P.J. (deposition date: 2020-06-05, release date: 2020-11-25, Last modification date: 2024-04-03) |
Primary citation | Eaglesham, J.B.,McCarty, K.L.,Kranzusch, P.J. Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict. Elife, 9:-, 2020 Cited by PubMed: 33191912DOI: 10.7554/eLife.59753 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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