6XB3

Structure of AcNPV poxin in post-reactive state with Gp[2'-5']Ap[3']

Summary for 6XB3

Entry DOI	10.2210/pdb6xb3/pdb
Descriptor	Poxin, 2',5'-GpAp (3 entities in total)
Functional Keywords	poxin, p26, baculovirus, nucleopolyhedrovirus, innate immunity, nuclease, cgas, cgamp, sting, hydrolase
Biological source	Autographa californica nuclear polyhedrosis virus (AcMNPV)
Total number of polymer chains	16
Total formula weight	449470.70
Authors	Eaglesham, J.B.,McCarty, K.L.,Kranzusch, P.J. (deposition date: 2020-06-05, release date: 2020-11-25, Last modification date: 2024-04-03)
Primary citation	Eaglesham, J.B.,McCarty, K.L.,Kranzusch, P.J. Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict. Elife, 9:-, 2020 Cited by PubMed: 33191912 DOI: 10.7554/eLife.59753 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation