7MBX
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![BU of 7mbx by Molmil](/molmil-images/mine/7mbx) | Human Cholecystokinin 1 receptor (CCK1R) Gs complex | 分子名称: | CHOLESTEROL HEMISUCCINATE, Cholecystokinin receptor type A, Cholecystokinin-8, ... | 著者 | Mobbs, J.I, Belousoff, M.J, Danev, R, Thal, D.M, Sexton, P.M. | 登録日 | 2021-04-01 | 公開日 | 2021-05-26 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (1.95 Å) | 主引用文献 | Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity. Plos Biol., 19, 2021
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7MBY
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![BU of 7mby by Molmil](/molmil-images/mine/7mby) | Human Cholecystokinin 1 receptor (CCK1R) Gq chimera (mGsqi) complex | 分子名称: | CHOLESTEROL HEMISUCCINATE, Cholecystokinin receptor type A, Cholecystokinin-8, ... | 著者 | Mobbs, J.I, Belousoff, M.J, Danev, R, Thal, D.M, Sexton, P.M. | 登録日 | 2021-04-01 | 公開日 | 2021-05-26 | 最終更新日 | 2021-07-14 | 実験手法 | ELECTRON MICROSCOPY (2.44 Å) | 主引用文献 | Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity. Plos Biol., 19, 2021
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7O81
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![BU of 7o81 by Molmil](/molmil-images/mine/7o81) | Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
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7O7Y
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![BU of 7o7y by Molmil](/molmil-images/mine/7o7y) | Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution) | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
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7O80
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![BU of 7o80 by Molmil](/molmil-images/mine/7o80) | Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
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7MDZ
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![BU of 7mdz by Molmil](/molmil-images/mine/7mdz) | 80S rabbit ribosome stalled with benzamide-CHX | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S21, ... | 著者 | Koga, Y, Hoang, E.M, Park, Y, Keszei, A.F.A, Murray, J, Shao, S, Liau, B.B. | 登録日 | 2021-04-06 | 公開日 | 2021-09-01 | 最終更新日 | 2021-09-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. J.Am.Chem.Soc., 143, 2021
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7MQA
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![BU of 7mqa by Molmil](/molmil-images/mine/7mqa) | Cryo-EM structure of the human SSU processome, state post-A1 | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Vanden Broeck, A, Singh, S, Klinge, S. | 登録日 | 2021-05-05 | 公開日 | 2021-09-22 | 最終更新日 | 2021-09-29 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
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7MQ8
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![BU of 7mq8 by Molmil](/molmil-images/mine/7mq8) | Cryo-EM structure of the human SSU processome, state pre-A1 | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Vanden Broeck, A, Singh, S, Klinge, S. | 登録日 | 2021-05-05 | 公開日 | 2021-09-22 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
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7MQ9
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![BU of 7mq9 by Molmil](/molmil-images/mine/7mq9) | Cryo-EM structure of the human SSU processome, state pre-A1* | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Vanden Broeck, A, Singh, S, Klinge, S. | 登録日 | 2021-05-05 | 公開日 | 2021-09-22 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
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7O7F
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![BU of 7o7f by Molmil](/molmil-images/mine/7o7f) | Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist | 分子名称: | C-C chemokine receptor type 5, C-C motif chemokine 5, Fab antibody fragment heavy chain, ... | 著者 | Isaikina, P, Tsai, C.-J, Dietz, N.B, Pamula, F, Goldie, K.N, Schertler, G.F.X, Maier, T, Stahlberg, H, Deupi, X, Grzesiek, S. | 登録日 | 2021-04-13 | 公開日 | 2021-06-30 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist. Sci Adv, 7, 2021
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7NWG
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![BU of 7nwg by Molmil](/molmil-images/mine/7nwg) | Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. | 分子名称: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | 登録日 | 2021-03-16 | 公開日 | 2021-07-07 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
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7NWI
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![BU of 7nwi by Molmil](/molmil-images/mine/7nwi) | Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ... | 著者 | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | 登録日 | 2021-03-16 | 公開日 | 2021-07-07 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
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7NWH
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![BU of 7nwh by Molmil](/molmil-images/mine/7nwh) | Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. | 分子名称: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | 登録日 | 2021-03-16 | 公開日 | 2021-07-07 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
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8B3F
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![BU of 8b3f by Molmil](/molmil-images/mine/8b3f) | Pol II-CSB-CSA-DDB1-ELOF1 | 分子名称: | DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... | 著者 | Kokic, G, Cramer, P. | 登録日 | 2022-09-16 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Pol II-CSB-CSA-DDB1-ELOF1 structure. To Be Published
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8B3I
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![BU of 8b3i by Molmil](/molmil-images/mine/8b3i) | CRL4CSA-E2-Ub (state 2) | 分子名称: | Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-8, ... | 著者 | Kokic, G, Cramer, P. | 登録日 | 2022-09-16 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | C(N)RL4CSA-E2-Ub (state 2) To Be Published
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8B3D
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![BU of 8b3d by Molmil](/molmil-images/mine/8b3d) | |
8BB2
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![BU of 8bb2 by Molmil](/molmil-images/mine/8bb2) | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #2) | 分子名称: | 1,2-ETHANEDIOL, Elongin-B, Elongin-C, ... | 著者 | Kraemer, A, Doelle, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-10-12 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #2) To Be Published
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8BB3
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![BU of 8bb3 by Molmil](/molmil-images/mine/8bb3) | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #1) | 分子名称: | 1,2-ETHANEDIOL, Elongin-B, Elongin-C, ... | 著者 | Kraemer, A, Doelle, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-10-12 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #1) To Be Published
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8BB5
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![BU of 8bb5 by Molmil](/molmil-images/mine/8bb5) | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with Aryl linker | 分子名称: | 1,2-ETHANEDIOL, Elongin-B, Elongin-C, ... | 著者 | Kraemer, A, Doelle, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-10-12 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization. Cell Chem Biol, 30, 2023
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8BB4
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![BU of 8bb4 by Molmil](/molmil-images/mine/8bb4) | Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with C3 linker | 分子名称: | Elongin-B, Elongin-C, WD repeat-containing protein 5, ... | 著者 | Kraemer, A, Doelle, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-10-12 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization. Cell Chem Biol, 30, 2023
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8BWY
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![BU of 8bwy by Molmil](/molmil-images/mine/8bwy) | In situ outer dynein arm from Chlamydomonas reinhardtii in a pre-power stroke state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calmodulin, ... | 著者 | Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T. | 登録日 | 2022-12-07 | 公開日 | 2023-05-10 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (38 Å) | 主引用文献 | ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography. Embo J., 42, 2023
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8BTK
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![BU of 8btk by Molmil](/molmil-images/mine/8btk) | Structure of the TRAP complex with the Sec translocon and a translating ribosome | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Jaskolowski, M, Jomaa, A, Gamerdinger, M, Shrestha, S, Leibundgut, M, Deuerling, E, Ban, N. | 登録日 | 2022-11-29 | 公開日 | 2023-05-24 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular basis of the TRAP complex function in ER protein biogenesis. Nat.Struct.Mol.Biol., 30, 2023
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8BX8
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![BU of 8bx8 by Molmil](/molmil-images/mine/8bx8) | In situ outer dynein arm from Chlamydomonas reinhardtii in the post-power stroke state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... | 著者 | Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T. | 登録日 | 2022-12-08 | 公開日 | 2023-05-10 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (30.299999 Å) | 主引用文献 | ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography. Embo J., 42, 2023
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8BN3
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![BU of 8bn3 by Molmil](/molmil-images/mine/8bn3) | Yeast 80S, ES7s delta, eIF5A, Stm1 containing | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | 著者 | Dimitrova-Paternoga, L, Paternoga, H, Wilson, D.N. | 登録日 | 2022-11-12 | 公開日 | 2024-01-10 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes. Nucleic Acids Res., 52, 2024
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8CAH
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![BU of 8cah by Molmil](/molmil-images/mine/8cah) | Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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