8BB3

Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #1)

Summary for 8BB3

• Entry DOI: 10.2210/pdb8bb3/pdb
• Descriptor: Elongin-B, Elongin-C, von Hippel-Lindau disease tumor suppressor, ... (9 entities in total)
• Functional Keywords: e3-ligase, wdr5, vhl, elongin, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 79912.05

Authors

Kraemer, A.,Doelle, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2022-10-12, release date: 2022-11-09, Last modification date: 2024-01-31)

• Primary citation: Kraemer, A.,Doelle, A.,Knapp, S.,Structural Genomics Consortium (SGC); Structure of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC with PEG linker (conformation #1); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)