7MBX
Human Cholecystokinin 1 receptor (CCK1R) Gs complex
Summary for 7MBX
Entry DOI | 10.2210/pdb7mbx/pdb |
EMDB information | 23749 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total) |
Functional Keywords | gpcr, membrane protein, membrane protein-signaling protein complex, membrane protein/signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 156607.26 |
Authors | Mobbs, J.I.,Belousoff, M.J.,Danev, R.,Thal, D.M.,Sexton, P.M. (deposition date: 2021-04-01, release date: 2021-05-26, Last modification date: 2021-07-14) |
Primary citation | Mobbs, J.I.,Belousoff, M.J.,Harikumar, K.G.,Piper, S.J.,Xu, X.,Furness, S.G.B.,Venugopal, H.,Christopoulos, A.,Danev, R.,Wootten, D.,Thal, D.M.,Miller, L.J.,Sexton, P.M. Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity. Plos Biol., 19:e3001295-e3001295, 2021 Cited by PubMed: 34086670DOI: 10.1371/journal.pbio.3001295 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (1.95 Å) |
Structure validation
Download full validation report