4Z53
| Quinolone(Trovafloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae | 分子名称: | DNA topoisomerase 4 subunit B,DNA topoisomerase 4 subunit A, E-site DNA, MAGNESIUM ION, ... | 著者 | Laponogov, I, Veselkov, D.A, Pan, X.-S, Selvarajah, J, Crevel, I.M.-T, Fisher, L.M, Sanderson, M.R. | 登録日 | 2015-04-02 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | 主引用文献 | Structural studies of the drug-stabilized cleavage complexes of topoisomerase IV and gyrase from Streptococcus pneumoniae To Be Published
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4GJP
| Crystal structure of the TAL effector dHax3 bound to dsDNA containing repetitive methyl-CpG | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*CP*T)-3'), Hax3, ... | 著者 | Yan, N, Deng, D, Yan, C.Y, Yin, P, Pan, X.J, Shi, Y.G. | 登録日 | 2012-08-10 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of a protein complex To be Published
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6Z2X
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6Z2W
| Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP | 分子名称: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Yates, L.A, Zhang, X. | 登録日 | 2020-05-18 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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8SXT
| Structure of LINE-1 ORF2p with template:primer hybrid | 分子名称: | DNA primer, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... | 著者 | van Eeuwen, T, Taylor, M.S, Rout, M.P. | 登録日 | 2023-05-24 | 公開日 | 2024-01-10 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626, 2024
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6QWF
| The Transcriptional Regulator PrfA-A94V mutant from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif | 分子名称: | DNA (30-MER), GLYCEROL, Listeriolysin positive regulatory factor A | 著者 | Hall, M, Grundstrom, C, Hansen, S, Brannstrom, K, Johansson, J, Sauer-Eriksson, A.E. | 登録日 | 2019-03-05 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes. J.Bacteriol., 202, 2020
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6QWK
| The Transcriptional Regulator PrfA-L140F mutant from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif | 分子名称: | DNA (30-MER), GLYCEROL, Listeriolysin positive regulatory factor A | 著者 | Hall, M, Grundstrom, C, Hansen, S, Brannstrom, K, Johansson, J, Sauer-Eriksson, A.E. | 登録日 | 2019-03-05 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes. J.Bacteriol., 202, 2020
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6QWH
| The Transcriptional Regulator PrfA-L140H mutant from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif | 分子名称: | DNA (30-MER), GLYCEROL, Listeriolysin positive regulatory factor A | 著者 | Hall, M, Grundstrom, C, Hansen, S, Brannstrom, K, Johansson, J, Sauer-Eriksson, A.E. | 登録日 | 2019-03-05 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes. J.Bacteriol., 202, 2020
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6QWM
| The Transcriptional Regulator PrfA-A218G mutant from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif | 分子名称: | DNA (30-MER), GLYCEROL, Listeriolysin positive regulatory factor A | 著者 | Hall, M, Grundstrom, C, Hansen, S, Brannstrom, K, Johansson, J, Sauer-Eriksson, A.E. | 登録日 | 2019-03-05 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes. J.Bacteriol., 202, 2020
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100D
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8GUJ
| Bre1-nucleosome complex (Model II) | 分子名称: | DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | 著者 | Onishi, S, Sato, K, Hamada, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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8GUI
| Bre1-nucleosome complex (Model I) | 分子名称: | DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | 著者 | Onishi, S, Hamada, K, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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8R6R
| Mycobacterium smegnatis RNA polymerase RP2-like transcription initiation complex with SigmaA, RbpA and open promoter DNA | 分子名称: | DNA 50-MER, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Koval, T, Krasny, L, Dohnalek, J, Kouba, T. | 登録日 | 2023-11-22 | 公開日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | 主引用文献 | Molecular insights into RNA polymerase recycling by mycobacterial HelD To Be Published
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7Z6O
| X-Ray studies of Ku70/80 reveal the binding site for IP6 | 分子名称: | DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*AP*AP*AP*CP*TP*AP*AP*AP*AP*AP*C)-3'), INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Varela, P.F, Charbonnier, J.B. | 登録日 | 2022-03-14 | 公開日 | 2023-08-30 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction. Nucleic Acids Res., 51, 2023
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1TRO
| CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION | 分子名称: | DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN | 著者 | Otwinowski, Z, Schevitz, R.W, Zhang, R.-G, Lawson, C.L, Joachimiak, A, Marmorstein, R, Luisi, B.F, Sigler, P.B. | 登録日 | 1992-08-30 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of trp repressor/operator complex at atomic resolution. Nature, 335, 1988
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6GO3
| TdT chimera (Loop1 of pol mu) - apoenzyme | 分子名称: | DNA nucleotidylexotransferase,DNA-directed DNA/RNA polymerase mu,DNA nucleotidylexotransferase | 著者 | Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M. | 登録日 | 2018-06-01 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294, 2019
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4Z2E
| Quinolone(Trovafloxacin)-DNA cleavage complex of gyrase from S. pneumoniae | 分子名称: | DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION, ... | 著者 | Laponogov, I, Veselkov, D.A, Pan, X.-S, Selvarajah, J, Crevel, I.M.-T, Fisher, L.M, Sanderson, M.R. | 登録日 | 2015-03-29 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | Structural studies of the drug-stabilized cleavage complexes of topoisomerase IV and gyrase from Streptococcus pneumoniae To Be Published
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1DML
| CRYSTAL STRUCTURE OF HERPES SIMPLEX UL42 BOUND TO THE C-TERMINUS OF HSV POL | 分子名称: | DNA POLYMERASE, DNA POLYMERASE PROCESSIVITY FACTOR | 著者 | Zuccola, H.J, Filman, D.J, Coen, D.M, Hogle, J.M. | 登録日 | 1999-12-14 | 公開日 | 2000-03-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase. Mol.Cell, 5, 2000
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6PR5
| Cryo-EM structure of HzTransib strand transfer complex (STC) | 分子名称: | DNA (30-MER), DNA (39-MER), DNA (5'-D(*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*TP*CP*A)-3'), ... | 著者 | Liu, C, Yang, Y, Schatz, D.G. | 登録日 | 2019-07-10 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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8OK2
| Bipartite interaction of TOPBP1 with the GINS complex | 分子名称: | DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, DNA replication complex GINS protein PSF3, ... | 著者 | Day, M, Oliver, A.W, Pearl, L.H. | 登録日 | 2023-03-26 | 公開日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | TopBP1 utilises a bipartite GINS binding mode to support genome replication. Nat Commun, 15, 2024
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6M4G
| Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2 | 分子名称: | DNA (93-MER), Histone H2A-Bbd type 2/3, Histone H2B type 2-E, ... | 著者 | Zhou, M, Dai, L.C, Li, C.M, Shi, L.X, Huang, Y, Guo, Z.Q. | 登録日 | 2020-03-06 | 公開日 | 2020-09-23 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2. Embo J., 40, 2021
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6M4H
| Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2 | 分子名称: | DNA (103-MER), Histone H2A-Bbd type 2/3, Histone H2B type 2-E, ... | 著者 | Zhou, M, Dai, L.C, Li, C.M, Shi, L.X, Huang, Y, Guo, Z.Q. | 登録日 | 2020-03-07 | 公開日 | 2020-09-23 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2. Embo J., 40, 2021
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3WOE
| Crystal structure of P23-45 gp39 (6-109) bound to Thermus thermophilus RNA polymerase beta-flap domain | 分子名称: | DNA-directed RNA polymerase subunit beta, Putative uncharacterized protein | 著者 | Tagami, S, Sekine, S, Minakhin, L, Esyunina, D, Akasaka, R, Shirouzu, M, Kulbachinskiy, A, Severinov, K, Yokoyama, S. | 登録日 | 2013-12-26 | 公開日 | 2014-03-12 | 最終更新日 | 2015-03-25 | 実験手法 | X-RAY DIFFRACTION (2.351 Å) | 主引用文献 | Structural basis for promoter specificity switching of RNA polymerase by a phage factor. Genes Dev., 28, 2014
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1NT9
| Complete 12-subunit RNA polymerase II | 分子名称: | DNA-DIRECTED RNA POLYMERASE II 13.6 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT, ... | 著者 | Armache, K.-J, Kettenberger, H, Cramer, P. | 登録日 | 2003-01-29 | 公開日 | 2003-04-22 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Architecture of initiation-competent 12-subunit RNA polymerase II Proc.Natl.Acad.Sci.USA, 100, 2003
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8HAG
| Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (3.2 angstrom resolution) | 分子名称: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | 登録日 | 2022-10-26 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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