6Z2W
Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP
Summary for 6Z2W
| Entry DOI | 10.2210/pdb6z2w/pdb |
| EMDB information | 11050 |
| Descriptor | DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total) |
| Functional Keywords | serine/threonine protein kinase, complex, dna damage response, checkpoint control, hydrolase |
| Biological source | Saccharomyces cerevisiae S288C More |
| Total number of polymer chains | 4 |
| Total formula weight | 721601.24 |
| Authors | Yates, L.A.,Zhang, X. (deposition date: 2020-05-18, release date: 2020-11-11, Last modification date: 2021-02-10) |
| Primary citation | Tannous, E.A.,Yates, L.A.,Zhang, X.,Burgers, P.M. Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28:50-61, 2021 Cited by PubMed: 33169019DOI: 10.1038/s41594-020-00522-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.82 Å) |
Structure validation
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