6Z2W
Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (D, C) | DNA damage checkpoint protein LCD1 | polymer | 747 | 86533.6 | 2 | UniProt (Q04377) Pfam (PF09798) | Saccharomyces cerevisiae S288C | DNA damage checkpoint protein 2,Lethal,checkpoint-defective,DNA damage-sensitive protein 1 |
| 2 | C, D (E, F) | Serine/threonine-protein kinase MEC1 | polymer | 2368 | 273646.8 | 2 | UniProt (P38111) Pfam (PF08064) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) | Saccharomyces cerevisiae S288C | ATR homolog,DNA-damage checkpoint kinase MEC1,Mitosis entry checkpoint protein 1 |
| 3 | E, I (E, F) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | F, J (E, F) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | G, H, K, L (E, F) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | M, N (E, F) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
E, F: 1 - 2368 (UniProt: P38111)
| PDB | External Database | Details |
|---|---|---|
| Leu 2244 | Phe 2244 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 720360.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1240.4 | |
| All* | Total formula weight | 721601.2 |
