6QWH

The Transcriptional Regulator PrfA-L140H mutant from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif

Summary for 6QWH

Entry DOI	10.2210/pdb6qwh/pdb
Descriptor	Listeriolysin positive regulatory factor A, DNA (30-MER), GLYCEROL, ... (5 entities in total)
Functional Keywords	transcription regulator, activation, listeria monocytogenes, transcription, virulence factor, dna binding protein
Biological source	Listeria monocytogenes More
Total number of polymer chains	4
Total formula weight	73499.07
Authors	Hall, M.,Grundstrom, C.,Hansen, S.,Brannstrom, K.,Johansson, J.,Sauer-Eriksson, A.E. (deposition date: 2019-03-05, release date: 2020-04-01, Last modification date: 2024-01-24)
Primary citation	Hansen, S.,Hall, M.,Grundstrom, C.,Brannstrom, K.,Sauer-Eriksson, A.E.,Johansson, J. A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes. J.Bacteriol., 202:-, 2020 Cited by PubMed: 32179627 DOI: 10.1128/JB.00115-20 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation