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1FAI
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THREE-DIMENSIONAL STRUCTURE OF TWO CRYSTAL FORMS OF FAB R19.9, FROM A MONOCLONAL ANTI-ARSONATE ANTIBODY
分子名称: IGG2B-KAPPA R19.9 FAB (HEAVY CHAIN), IGG2B-KAPPA R19.9 FAB (LIGHT CHAIN)
著者Lascombe, M.B, Alzari, P.M, Poljak, R.J, Nisonoff, A.
登録日1992-05-27
公開日1992-10-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Three-dimensional structure of two crystal forms of FabR19.9 from a monoclonal anti-arsonate antibody.
Proc.Natl.Acad.Sci.USA, 89, 1992
6PDS
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BU of 6pds by Molmil
Vaccine-elicited NHP FP-targeting antibody 0PV-a.04 in complex with HIV fusion peptide (residue 512-519)
分子名称: HIV-1 fusion peptide residue 512-519, SULFATE ION, antibody 0PV-a.04 heavy chain, ...
著者Xu, K, Liu, K, Wang, Y, Kwong, P.D.
登録日2019-06-19
公開日2020-06-24
実験手法X-RAY DIFFRACTION (1.893 Å)
主引用文献Modular recognition of antigens provides a mechanism that improves vaccine-elicited antibody-class frequencies
To Be Published
8W9J
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BU of 8w9j by Molmil
Crystal structure of human CLEC12A ectodomain complexed with 50C1 Fab
分子名称: Anti-human CLEC12A antibody 50C1 heavy chain, Anti-human CLEC12A antibody 50C1 light chain, C-type lectin domain family 12 member A
著者Mori, S, Nagae, M, Yamasaki, S.
登録日2023-09-05
公開日2024-03-06
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
8GSP
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BU of 8gsp by Molmil
Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody W2
分子名称: A/WH/CHA/09 VP1, A/WH/CHA/09 VP2, A/WH/CHA/09 VP3, ...
著者He, Y, Li, K.
登録日2022-09-06
公開日2023-10-11
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies.
Plos Pathog., 19, 2023
3HC0
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BU of 3hc0 by Molmil
BHA10 IgG1 wild-type Fab - antibody directed at human LTBR
分子名称: ACETATE ION, IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN, ...
著者Arndt, J.W, Jordan, J.L, Lugovskoy, A, Wang, D.
登録日2009-05-05
公開日2009-08-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural understanding of stabilization patterns in engineered bispecific Ig-like antibody molecules
Proteins, 77, 2009
4J8R
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BU of 4j8r by Molmil
Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment
分子名称: Heavy chain of POM2 Fab, Light chain of POM2 Fab, Major prion protein
著者Swayampakula, M, Baral, P.K, Kav, N.N.V, Aguzzi, A, James, M.N.G.
登録日2013-02-14
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody.
Protein Sci., 22, 2013
2G57
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BU of 2g57 by Molmil
Structure of the Phosphorylation Motif of the oncogenic Protein beta-Catenin Recognized By a Selective Monoclonal Antibody
分子名称: Beta-catenin
著者Megy, S, Bertho, G, Gharbi-Benarous, J, Baleux, F, Benarous, R, Girault, J.P.
登録日2006-02-22
公開日2006-03-28
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献STD and TRNOESY NMR studies for the epitope mapping of the phosphorylation motif of the oncogenic protein beta-catenin recognized by a selective monoclonal antibody
Febs Lett., 580, 2006
3HC3
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BU of 3hc3 by Molmil
BHA10 IgG1 Fab double mutant variant - antibody directed at human LTBR
分子名称: ACETATE ION, IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN, ...
著者Arndt, J.W, Jordan, J.L, Lugovskoy, A, Wang, D.
登録日2009-05-05
公開日2009-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural understanding of stabilization patterns in engineered bispecific Ig-like antibody molecules
Proteins, 77, 2009
3QG6
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BU of 3qg6 by Molmil
Structural Basis for Ligand Recognition and Discrimination of a Quorum Quenching Antibody
分子名称: AP4-24H11 Heavy Chain, AP4-24H11 Light Chain, Agr autoinducing peptide, ...
著者Kirchdoerfer, R.N, Janda, J.D, Kaufmann, G.F, Wilson, I.A.
登録日2011-01-24
公開日2011-03-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody.
J.Biol.Chem., 286, 2011
8UWA
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BU of 8uwa by Molmil
VH1-18 QxxV class antibody 09-1B12 bound to A/Perth/16/2009 H3N2 hemagglutinin
分子名称: 09-1B12 heavy chain, 09-1B12 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Maurer, D.P.
登録日2023-11-06
公開日2024-05-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (4.02 Å)
主引用文献Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Immunity, 57, 2024
8V2E
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BU of 8v2e by Molmil
Crystal structure of B055 scaffold boost immunogen in complex with a mature 10E8 Fab
分子名称: 10E8 EPITOPE SCAFFOLD B055, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 10E8 FAB HEAVY CHAIN, ...
著者Cho, S.Y, Wilson, I.A.
登録日2023-11-22
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8GRR
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BU of 8grr by Molmil
Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody W125
分子名称: A/WH/CHA/09 VP1, A/WH/CHA/09 VP2, A/WH/CHA/09 VP3, ...
著者He, Y, Kun, L.
登録日2022-09-02
公開日2023-10-11
最終更新日2023-12-06
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies.
Plos Pathog., 19, 2023
6E5P
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BU of 6e5p by Molmil
Backbone model based on cryo-EM map at 8.5 A of domain-swapped, glycan-reactive, neutralizing antibody 2G12 bound to HIV-1 Env BG505 DS-SOSIP, which was also bound to CD4-binding site antibody VRC03
分子名称: 2G12 Light chain, 2G12 heavy chain, Envelope glycoprotein gp120, ...
著者Acharya, P, Kwong, P.D.
登録日2018-07-21
公開日2019-02-13
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition.
Structure, 27, 2019
8TJT
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BU of 8tjt by Molmil
The Fab fragment of an anti-glucagon receptor (GCGR) antibody
分子名称: anti-GCGR Fab heavy chain, anti-GCGR Fab light chain
著者Dai, J, Carter, P.J, Sudhamsu, J, Kung, J.
登録日2023-07-24
公開日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG 1 antibody.
Mabs, 16, 2024
4JHW
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BU of 4jhw by Molmil
Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25
分子名称: D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0
著者Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S.
登録日2013-03-05
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
3HC4
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BU of 3hc4 by Molmil
BHA10 IgG1 Fab quadruple mutant variant - antibody directed at human LTBR
分子名称: ACETATE ION, IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN, ...
著者Arndt, J.W, Jordan, J.L, Lugovskoy, A, Wang, D.
登録日2009-05-05
公開日2009-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structural understanding of stabilization patterns in engineered bispecific Ig-like antibody molecules
Proteins, 77, 2009
3CSY
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BU of 3csy by Molmil
Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein GP1, ...
著者Lee, J.E, Fusco, M.L, Hessell, A.J, Oswald, W.B, Burton, D.R, Saphire, E.O.
登録日2008-04-10
公開日2008-07-08
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor.
Nature, 454, 2008
1GIG
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BU of 1gig by Molmil
REFINED THREE-DIMENSIONAL STRUCTURE OF THE FAB FRAGMENT OF A MURINE IGG1, LAMBDA ANTIBODY
分子名称: IGG1-KAPPA HC19 FAB (HEAVY CHAIN), IGG1-KAPPA HC19 FAB (LIGHT CHAIN)
著者Bizebard, T, Knossow, M.
登録日1993-01-20
公開日1994-04-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined three-dimensional structure of the Fab fragment of a murine IgGl,lambda antibody.
Acta Crystallogr.,Sect.D, 50, 1994
5TL5
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BU of 5tl5 by Molmil
COMPLEX BETWEEN HUMAN CD27 AND ANTIBODY M2177
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ...
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2016-10-10
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of CD27 in complex with a neutralizing noncompeting antibody.
Acta Crystallogr F Struct Biol Commun, 73, 2017
1E4W
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BU of 1e4w by Molmil
crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment
分子名称: CHLORIDE ION, CYCLIC PEPTIDE, NICKEL (II) ION, ...
著者Hahn, M, Winkler, D, Misselwitz, R, Wessner, H, Welfle, K, Zahn, G, Schneider-Mergener, J, Hoehne, W.
登録日2000-07-12
公開日2001-07-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Cross-Reactive Binding of Cyclic Peptides to an Anti-Tgf Alpha Antibody Fab Fragment: An X-Ray Structural and Thermodynamic Analysis
J.Mol.Biol., 314, 2001
8VRR
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BU of 8vrr by Molmil
4H11-scFv antibody
分子名称: 4H11 scFv chain
著者Lee, K, Perry, K, Yeku, O.O, Spriggs, D.R.
登録日2024-01-22
公開日2024-04-03
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural basis for antibody recognition of the proximal MUC16 ectodomain.
J Ovarian Res, 17, 2024
8FSL
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BU of 8fsl by Molmil
Human Mesothelin bound to a neutralizing VH domain antibody
分子名称: Mesothelin, VH domain
著者Calero, G.
登録日2023-01-10
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Preclinical assessment of a novel human antibody VH domain targeting mesothelin as an antibody-drug conjugate.
Mol Ther Oncolytics, 31, 2023
6CMI
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BU of 6cmi by Molmil
Crystal Structure of the Hendra Virus Attachment G Glycoprotein Bound to a Potent Cross-Reactive Neutralizing Human Monoclonal Antibody m102.3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G, ...
著者Xu, K, Nikolov, D.
登録日2018-03-05
公開日2018-04-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody.
PLoS Pathog., 9, 2013
6EV2
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Crystal structure of antibody against schizophyllan in complex with laminarihexaose
分子名称: Heavy chain, Light chain, beta-D-glucopyranose, ...
著者Sung, K.H, Josewski, J, Duebel, S, Blankenfeldt, W, Rau, U.
登録日2017-11-01
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Structural insights into antigen recognition of an anti-beta-(1,6)-beta-(1,3)-D-glucan antibody.
Sci Rep, 8, 2018
2FGW
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X-RAY STRUCTURES OF FRAGMENTS FROM BINDING AND NONBINDING VERSIONS OF A HUMANIZED ANTI-CD18 ANTIBODY: STRUCTURAL INDICATIONS OF THE KEY ROLE OF VH RESIDUES 59 TO 65
分子名称: H52 FAB (HEAVY CHAIN), H52 FAB (LIGHT CHAIN)
著者Eigenbrot, C, Kessler, J.
登録日1994-01-16
公開日1994-04-30
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: structural indications of the key role of VH residues 59 to 65.
Proteins, 18, 1994

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