8TJT

The Fab fragment of an anti-glucagon receptor (GCGR) antibody

Summary for 8TJT

• Entry DOI: 10.2210/pdb8tjt/pdb
• Descriptor: anti-GCGR Fab light chain, anti-GCGR Fab heavy chain (3 entities in total)
• Functional Keywords: antibody, glucagon receptor, fab fragment, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 8
• Total formula weight: 190723.88

Authors

Dai, J.,Carter, P.J.,Sudhamsu, J.,Kung, J. (deposition date: 2023-07-24, release date: 2024-02-14)

• Primary citation: Dai, J.,Izadi, S.,Zarzar, J.,Wu, P.,Oh, A.,Carter, P.J.; Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG 1 antibody.; Mabs, 16:2304282-2304282, 2024; PubMed: 38269489; DOI: 10.1080/19420862.2024.2304282

Experimental method

X-RAY DIFFRACTION (2.7 Å)