3CSY
Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor
Summary for 3CSY
Entry DOI | 10.2210/pdb3csy/pdb |
Descriptor | Fab KZ52 heavy chain, Fab KZ52 light chain, Envelope glycoprotein GP1, ... (8 entities in total) |
Functional Keywords | glycoprotein-antibody complex, immune system-viral protein complex, immune system/viral protein |
Biological source | Homo sapiens (human) More |
Cellular location | GP2: Virion membrane; Single-pass type I membrane protein. GP1: Virion membrane; Peripheral membrane protein. GP2-delta: Secreted: Q05320 GP2: Virion membrane; Single-pass type I membrane protein (By similarity). GP1: Virion membrane; Peripheral membrane protein (By similarity). GP2-delta: Secreted (By similarity): P87666 |
Total number of polymer chains | 16 |
Total formula weight | 406070.53 |
Authors | Lee, J.E.,Fusco, M.L.,Hessell, A.J.,Oswald, W.B.,Burton, D.R.,Saphire, E.O. (deposition date: 2008-04-10, release date: 2008-07-08, Last modification date: 2021-10-20) |
Primary citation | Lee, J.E.,Fusco, M.L.,Hessell, A.J.,Oswald, W.B.,Burton, D.R.,Saphire, E.O. Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor. Nature, 454:177-182, 2008 Cited by PubMed: 18615077DOI: 10.1038/nature07082 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
Download full validation report