PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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6N3Q	Cryo-EM structure of the yeast Sec complex 分子名称: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... 著者 Park, E, Itskanov, S. 登録日 2018-11-16 公開日 2018-12-19 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Structure of the posttranslational Sec protein-translocation channel complex from yeast. Science, 363, 2019
5DGF	Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. 登録日 2015-08-27 公開日 2016-12-14 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
5U9F	3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure II) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Demo, G, Svidritskiy, E, Madireddy, R, Diaz-Avalos, R, Grant, T, Grigorieff, N, Sousa, D, Korostelev, A.A. 登録日 2016-12-16 公開日 2017-03-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mechanism of ribosome rescue by ArfA and RF2. Elife, 6, 2017
5VP2	Crystal structure of the Thermus thermophilus 70S ribosome in complex with madumycin II and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution 分子名称: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Osterman, I.A, Khabibullina, N.F, Komarova, E.S, Kasatsky, P, Kartsev, V.G, Bogdanov, A.A, Dontsova, O.A, Konevega, A.L, Sergiev, P.V, Polikanov, Y.S. 登録日 2017-05-04 公開日 2017-06-28 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state. Nucleic Acids Res., 45, 2017
5W4K	Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Metelev, M, Osterman, I.A, Ghilarov, D, Khabibullina, N.F, Yakimov, A, Shabalin, K, Utkina, I, Travin, D.Y, Komarova, E.S, Serebryakova, M, Artamonova, T, Khodorkovskii, M, Konevega, A.L, Sergiev, P.V, Severinov, K, Polikanov, Y.S. 登録日 2017-06-12 公開日 2017-08-30 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel. Nat. Chem. Biol., 13, 2017
5V8I	Thermus thermophilus 70S ribosome lacking ribosomal protein uS17 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Gregory, S.T, Jogl, G. 登録日 2017-03-22 公開日 2018-03-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structural robustness of the ribosome inferred from X-ray crystal structures of the 30S ribosomal subunit and the 70S ribosome lacking ribosomal protein uS17 To be published
5DM6	Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans 分子名称: 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... 著者 Kaminishi, T, Schedlbauer, A, Ochoa-Lizarralde, B, Connell, S.R, Fucini, P. 登録日 2015-09-08 公開日 2015-11-11 最終更新日 2016-02-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A. Nucleic Acids Res., 43, 2015
5VPO	The 70S P-site ASL SufA6 complex 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M. 登録日 2017-05-05 公開日 2018-09-26 最終更新日 2018-11-07 実験手法 X-RAY DIFFRACTION (3.34 Å) 主引用文献 Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5DM7	Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with hygromycin A 分子名称: 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... 著者 Kaminishi, T, Schedlbauer, A, Ochoa-Lizarralde, B, Connell, S.R, Fucini, P. 登録日 2015-09-08 公開日 2015-11-11 最終更新日 2015-11-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A. Nucleic Acids Res., 43, 2015
5WFS	70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-12 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
5UYM	70S ribosome bound with cognate ternary complex base-paired to A site codon, closed 30S (Structure III) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. 登録日 2017-02-24 公開日 2017-06-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
5UYQ	70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. 登録日 2017-02-24 公開日 2017-06-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
5UMD	Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Wong, W, Bai, X.-C, Brown, A, Scheres, S, Baum, J. 登録日 2017-01-27 公開日 2017-03-01 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis. Nat Microbiol, 2, 2017
4YBB	High-resolution structure of the Escherichia coli ribosome 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... 著者 Noeske, J, Wasserman, M.R, Terry, D.S, Altman, R.B, Blanchard, S.C, Cate, J.H.D. 登録日 2015-02-18 公開日 2015-03-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 High-resolution structure of the Escherichia coli ribosome. Nat.Struct.Mol.Biol., 22, 2015
5VPP	The 70S P-site tRNA SufA6 complex 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M. 登録日 2017-05-05 公開日 2018-09-26 最終更新日 2018-11-07 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5WF0	70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-11 公開日 2018-05-02 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
5DGV	Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog 分子名称: 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... 著者 Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. 登録日 2015-08-28 公開日 2016-12-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
5DC3	Complex of yeast 80S ribosome with non-modified eIF5A 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. 登録日 2015-08-23 公開日 2016-06-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome. J.Mol.Biol., 428, 2016
4XEJ	IRES bound to bacterial Ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Zhu, J, Korostelev, A, Noller, H.F, Donohue, J.P. 登録日 2014-12-23 公開日 2015-02-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Initiation of translation in bacteria by a structured eukaryotic IRES RNA. Nature, 519, 2015
5UYN	70S ribosome bound with near-cognate ternary complex not base-paired to A site codon (Structure I-nc) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. 登録日 2017-02-24 公開日 2017-06-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
5D8B	Crystal structure of T. thermophilus ribosome containing a P-site wobble mismatch 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Korostelev, A.A. 登録日 2015-08-17 公開日 2015-10-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.63 Å) 主引用文献 Ribosome Structure Reveals Preservation of Active Sites in the Presence of a P-Site Wobble Mismatch. Structure, 23, 2015
4ZER	Crystal structure of the Onc112 antimicrobial peptide bound to the Thermus thermophilus 70S ribosome 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16s ribosomal RNA, 23s ribosomal RNA, ... 著者 Seefeldt, A.C, Nguyen, F, Antunes, S, Perebaskine, N, Graf, M, Arenz, S, Inampudi, K.K, Douat, C, Guichard, G, Wilson, D.N, Innis, C.A. 登録日 2015-04-20 公開日 2015-05-20 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex. Nat.Struct.Mol.Biol., 22, 2015
5WFK	70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C3) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-12 公開日 2018-05-02 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
5E81	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with wobble pair 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. 登録日 2015-10-13 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
5UYP	70S ribosome bound with near-cognate ternary complex base-paired to A site codon, open 30S (Structure II-nc) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. 登録日 2017-02-24 公開日 2017-06-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017

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